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Basic Drug Discussion
Introductory-level drug and harm reduction advice. Use focus forums for complex queries
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Poly drug use and cycling to minimize dependency & tolerance risk - In other words this idiot's addicted to being high
placebonaut
Mar 21, 2026
7
8
9
Replies
162
Views
6K
Aug 19, 2026
Jung and Stoopid
R
Stimulants
Will taking concerta ruin the chill vibe of klonopin, methadone and weed?
RuffSamurai
Aug 8, 2026
Replies
5
Views
231
Aug 19, 2026
RuffSamurai
R
N
If cocaine blocks reuptake of dopamine..
new2drugs
Jun 20, 2023
5
6
7
Replies
124
Views
32K
Aug 19, 2026
lost weekend
D
Benzos
Flubromazepam vs bromazepam
dorian.927
Mar 17, 2025
Replies
3
Views
344
Aug 19, 2026
Octave77
O
HOW THE FUCK DO YOU GET EVERCLEAR DOWN
koolman69420
Aug 18, 2026
2
Replies
22
Views
431
Aug 19, 2026
placebonaut
Talking about bioavailability.
GaumarolBostich
Aug 18, 2026
Replies
6
Views
207
Aug 18, 2026
placebonaut
G
long term pain after plugging meth?
gbchris
Jul 28, 2026
Replies
3
Views
156
Aug 18, 2026
Halif2
H
C
Question about an unknown crystal substance and its effects
CrystalCurious
Aug 17, 2026
Replies
3
Views
117
Aug 18, 2026
placebonaut
K
Heroin
Not getting high, am I doing it wrong?
knightlite55
Aug 5, 2026
Replies
10
Views
393
Aug 18, 2026
knightlite55
K
M
Cannabis-induced anxiety after a bad trip , can diazepam (Valium) be a reliable safety net?
mazse
Aug 17, 2026
Replies
2
Views
164
Aug 18, 2026
agoraphobe
X
All 77 drugs i’ve tried - and some extra
XanaxBar
Aug 17, 2026
Replies
1
Views
165
Aug 18, 2026
evo4ever
E
S
Getting off of opiates, with no withdrawals, and no Suboxone or methadone - using ONLY Vitamin C - NOT A JOKE! READ THIS!
shamandafox
Jan 27, 2024
2
3
4
Replies
77
Views
10K
Aug 17, 2026
4DQSAR
Opioids
Tapentadol
coffeeshroom2.0
Jun 2, 2024
2
Replies
25
Views
4K
Aug 17, 2026
WellTram
W
O
Misc
LYRICA AND VISTARIL
onerhinoinamitten
Aug 14, 2026
Replies
7
Views
256
Aug 17, 2026
placebonaut
Harm Reduction
Alcohol substitute that can be used every 3-4 nights
Troppo
Jul 11, 2026
Replies
10
Views
455
Aug 16, 2026
rplate81
R
N
Some substance guidelines that have helped me -- take em or leave em
notsmokeymcpot42088
Aug 15, 2026
Replies
5
Views
154
Aug 16, 2026
probablyanxious
P
R
OXYCONTIN IS DONE!!!!if u abuse them find somethen new
ronthedon
May 24, 2010
16
17
18
Replies
351
Views
94K
Aug 16, 2026
Santa_Brings_Me_Oxys
P
Withdrawal, Gabapentin, and Dependence
probablyanxious
Aug 12, 2026
Replies
8
Views
287
Aug 16, 2026
probablyanxious
P
J
Cocaine
Disinfecting Suitcase Before Travel
JKS
Jul 20, 2026
Replies
14
Views
457
Aug 16, 2026
Ki3ly
Kava Is Nice But
agoraphobe
Jun 25, 2026
Replies
5
Views
452
Aug 16, 2026
Kurt Cobain
M
Meth and 7oh
mamamurph04
Feb 23, 2026
Replies
6
Views
779
Aug 16, 2026
Kurt Cobain
E
Opioids
Has anyone tried Naloxegol for constipation?
evo4ever
Dec 14, 2025
Replies
17
Views
633
Aug 16, 2026
Kurt Cobain
P
Opioids
Sr-17, 7oh, oxy, hydrocodone
pnillyg
Aug 3, 2026
Replies
1
Views
127
Aug 16, 2026
Kurt Cobain
i just ordered some sr-17018 tablets...
RUC4
Aug 6, 2026
Replies
6
Views
319
Aug 16, 2026
Kurt Cobain
C
Kratom and tramadol
candyslice
Aug 15, 2026
Replies
2
Views
114
Aug 16, 2026
Kurt Cobain
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