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Neuroscience and Pharmacology Discussion

Discussion of journal articles, drug science and other theoretical topics
negrogesic
Pharmacology An AI chatbot told me how to make tianeptine a more potent opioid
    • Like
    • Wow
Replies
16
Views
702
Fertile
Fertile
Fertile
Pharmacology Interesting paper on the A&H/Upjohn discovered benzamide opioids (U-47700 and relatives).
Replies
0
Views
188
Fertile
Fertile
Mr. Krinkle
Neuroscience Psychedelics Slip Past Cell Membranes When Treating Depression
    • Like
    • Heart
Replies
8
Views
518
Jabberwocky
Jabberwocky
M
Threshold Oral Naloxone Dose
Replies
7
Views
777
SpiralusSancti
S
Jabberwocky
An approach to treating schizophrenia with psychedelics (2022)
    • Like
    • Heart
2
Replies
34
Views
1K
SpiralusSancti
S
BourbonMac
Pharmacology Enhanced efficacy and reduced side effects of diazepam by kava combination
    • Like
Replies
4
Views
212
BourbonMac
BourbonMac
D
the Naloxone in Suboxone is active!
    • Like
2 3
Replies
56
Views
17K
Fertile
Fertile
Fertile
Adding an N-phenylethyl to a secondary amine
Replies
2
Views
228
Fertile
Fertile
Fertile
Catalyst experts - is their alternative to Wilkinson's catalyst that rearranges N-allyl to N-propenyl which is then removed via hydrogenation?
Replies
0
Views
198
Fertile
Fertile
Fertile
  • Locked
Deprotection of ethylcarbamate (secondary amine protecting group)
Replies
2
Views
225
VerbalTruist
VerbalTruist
Synaps3
Microdosing phenylpiperazines?
    • Hmm...
Replies
0
Views
179
Synaps3
Synaps3
S
Recreational drugs with silicon in their molecule
    • Like
Replies
19
Views
740
pharmakos
pharmakos
plumbus-nine
Why don't people in opioid maintenance develop breasts?
Replies
8
Views
865
Phobophobic
Phobophobic
Y
CYB004 Deuterated Dimethyltryptamine (DMT)
Replies
7
Views
301
fm3
fm3
dopamimetic
Natural Dissociatives?
2
Replies
26
Views
7K
Phobophobic
Phobophobic
A
Washing color out of ketamine
    • Like
Replies
1
Views
281
G_Chem
G
neversickanymore
Neuroscience Deep Brain Stimulation for treatment of Substance Use Disorders
    • Like
Replies
5
Views
385
neversickanymore
neversickanymore
theprinceoflife
Desfontainia Spinosa: A Natural Dissociative Without NMDA Antagonization?
Replies
0
Views
196
theprinceoflife
theprinceoflife
C
Vyvanse Tolerance Reset
Replies
2
Views
2K
deficiT
deficiT
JohnBoy2000
Ritalin (methylphenidate) differing effects, ORAL versus NASAL ROA - dependent on metabolites, or bioavailability?
Replies
3
Views
492
JohnBoy2000
JohnBoy2000
Shitake
Ways to enhace absorption, duration (half life) and potency.
Replies
1
Views
236
SpiralusSancti
S
Crankinit
Amphetamines and vitamin C
2
Replies
25
Views
18K
Jabberwocky
Jabberwocky
JohnBoy2000
David Sinclair (by way of Shinya_Yamanaka) research on reversing aging:
Replies
8
Views
313
Skorpio
Skorpio
JohnBoy2000
"Clot busting" drugs, blood thinners? Recommendations? Safety profiles?
    • Like
2
Replies
22
Views
1K
fastandbulbous
fastandbulbous
paracelsius
DEA back-off on scheduling Moxy and related tryptamines
    • Like
Replies
6
Views
489
yoyoman
Y
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