People sure have radically different responses from hyper-selective 5HT2A agonist such as most DOX and 25X-NBOMe drugs. I noticed the same variance with 25I-NBOMe. Even low doses caused extreme nausea, strong negative effects, and strong bitter taste in me. Other people didn't experience those negatives.
With any drug some people react differently. This appears especially true with these drugs. Start with an allergy test and stay safe.
Indeed. Everyone reacts differently. I appear to have the stomach of an ox and virtually nothing gives me nausea (except maybe olives☺).