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Dissociatives [Methoxetamine Subthread] Combinations - 2nd experiment

DroneLore said:
Why is mixing MXE and opiates more dangerous than with alcohol, in principal?
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The average opiate user is more likely to dose closer to OD levels with their drug of choice to get a nod than your average drinker is going to do. Also preference for ROAs where dosage is taken all at once with opies compounds this difference.
 
So wouldn't that earn opiates a spot in the "dose-dependent" category? Not every opiate user out there is just chasing a nod. There are two ways to look at this from the standpoint of HR:

1) It's best to keep opiates in the dangerous section, because this will discourage any mixing and therefore avoid any potential problems.
2) It's best to put them in the "dose-dependent" section, with a statement similar to what Never Knows Best has written, ie: "opiate doses sufficient to induce nodding are more likely to have severely harmful interactions when taken with MXE due to increased respiratory system depression."

I am in favor of the latter option. Let's say someone reads #1 and thinks "fuck it, I'll try it." So they bang three bags of dope and rail 60 mg of MXE. Sounds like they'd be riding that line between life and death.
Perhaps that same person would have chosen to shoot 2 or less bags of dope if they had seen mxe in #2. In this instance, because of dose-dependent warning, they may have the foresight to lower their opiate dose, taking into account that MXE WILL potentiate it.

Just my 2 cents.

And what about MXE and DXM? Is that just the doubling up of NMDAAs? There are few posts in this thread where individuals have mixed the two and lived to tell the tale. I'm not doubting that it's unsafe, I just want to know why. In fact, I think the rationale behind why each drug is in a given category should be given, so that people can take that information and apply it to other drugs that may not be explicitly listed here.
 
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I used Nasonex nasal spray (mometasone furoate monohydrate) for a month and had peculiar reactions when I used MXE on a few occasions during that time. At some point after the peak my sinuses and nostrils would start to feel really super super mega dry to the point it was very distracting and unnerving. Also experienced some fatique, headache and even slight nausea a couple times. Generally felt very unhealthy, like an allergic reaction. This phenomen would go away when MXE started to wear off. I've quit Nasonex since and haven't had any of these symptoms again. I also used 3-MeO-PCP two times during my Nasonex month and experienced the same uber dryness, although to a lesser extent. My ROAs were sublingual and oral.
 
After holing during the night, I decided to take an easter breakfast of about 12g of dried shrooms, plus a mixture of 20mg 2C-D and 30mg MXE rectally.

Physically I was OK, but the trip was aborted with benzos since it was unpleasantly intense. It was as if reality and my inner reality were visually superimposed on each other, in a quantum mechanical style. It was extremely interesting, but confusing and frightening. If it weren't for the positivity of the 2C-D and MXE, this would have been bad trip material. The mushrooms told me painful truths again.
 
Chris Timothy said:
After holing during the night, I decided to take an easter breakfast of about 12g of dried shrooms, plus a mixture of 20mg 2C-D and 30mg MXE rectally.

Physically I was OK, but the trip was aborted with benzos since it was unpleasantly intense. It was as if reality and my inner reality were visually superimposed on each other, in a quantum mechanical style. It was extremely interesting, but confusing and frightening. If it weren't for the positivity of the 2C-D and MXE, this would have been bad trip material. The mushrooms told me painful truths again.
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I think dissios generally combine badly with natural psychs such as mushrooms or mescaline, dmt seems to be fine though, maybe cause dmt doesnt have a spirit of it´s own, more like dmt brings you in to a spirit world where a bunch of entities can choose to interact with you if they wishh.
 
MXE + AMT -> 50mg of AMT with even little amounts of MXE (15mg) seems to completely change the nature of the trip, turning it from a recreational "look at the pretty colors" into a "should I be more selfless?" type introspection. Good or bad depending on what you're looking for (personally I enjoyed it).

MXE + Opiates -> Find this to be a really nice combination, 10-20mg adds a nice little extra to the opiate high without overpowering it. Any higher tends to become too stimulating.

MXE + Booze -> Can't decide if I like this or not. Very messy and fucked up so whilst not great for a club can be pretty fun if you're looking for getting trashed with your mates.

MXE + Stimulants -> Never really found this very useful, takes the nice stimulant clear-headedness and makes you feel more dumbed down.

MXE + Cannabis -> Cannabis powers up the MXE nicely (both body and head high), and I really like this combo.

MXE + AM-2201 -> Found it can cause A LOT of paranoia, but it is enjoyable in a very strange way, never experienced anything like it. Only lasts around half an hour which is helpful.


Hoping to try MXE + 5-Meo-Dalt at some point soon as I imagine them to have a nice synergy when combined in a low dose. Will report back in a couple of weeks :)
 
just acquired some 25I-NBOMe blotter dosed at 1mg each, along with another g of MXE. Thinking about combining the two tomorrow or wednesday. Anyone tried this particular combo before?
 
Methoxetamine + Melatonin seems to produce an extremely clear headed and euphoric high.

I've done this a few time now and each time it puts me in a place of extreme clear headedness and the best, almost indescribable euphoria.

There has got to be something to this.
 
Ondine said:
just acquired some 25I-NBOMe blotter dosed at 1mg each, along with another g of MXE. Thinking about combining the two tomorrow or wednesday. Anyone tried this particular combo before?
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I've done 2C-C-NBOMe and MXE and it was fine.
 
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Roostre said:
Methoxetamine + Melatonin seems to produce an extremely clear headed and euphoric high.

I've done this a few time now and each time it puts me in a place of extreme clear headedness and the best, almost indescribable euphoria.

There has got to be something to this.
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I've noticed that as well. I can't imagine why though, perhaps the body starts producing lower brain waves? I found that when using binaural beats to induce an alpha wave state, that it feels very, very similar to how I feel on melatonin + mxe. Any thoughts?
 
Combined MXE and 2c-I the other day. Started off with a 20mg oral MXE dose, and about an hour and a half later insufflated a mixed line of 20mg MXE and 8mg 2c-I. Not much in the way of visuals, but while I was peaking smoking cigs in the backyard I realized how awesome it is to be alive to literally just be able to sit and chill in the sunshine with no worries. Pretty damn euphoric to say the least, and the body high was amazing.
 
MXE potentiates opiates significantly. Keep this in mind if you're going to combine. THINK HARD ABOUT IT. And if you do it, keep one dose really low.
 
Been using MXE and 2c-P both insufflated in moderate doses with great success.

I found 2c-P (8mg insufflated with a bit of tolerance) alone to be rather boring, but 20mg bumps [of methoxetamine] every half hour or so until you reach a place where the profundity can't be ignored. Total ego death, absolute beauty.

MXE and small doses of suboxone seemed neutral and I don't generally use opiates, just a bit of suboxone at the end of the month when my 3mg klonopin reserves are down to a minimum, usually .25mg.

MXE and neurontin didn't feel like they potentiated one another all that much, but no negative effects were observed.

MXE and 5meomipt blurred the effects of the 5meo to the point where I couldn't rightly feel the 7mg 5meo. I had never taken the moxy beforehand and took it at the tail end of an MXE session (24 hours), but the effects were much more pleasurable and "mushroomish" than the MXE alone.

MXE and mindfulness meditation at the peak of the "hole" or however you'd phrase the pinnacle of the experience were a godsend. Listening to Thich Nhat Hahn leading a meditation on transience audio file was mindblowing after I found myself taken aback and hit hard with TOO much of the MXE, the afterglow lasted a full 10 hours until sleep was observed.

All of my experiments were with insufflated MXE. Does anyone know how rectal and/or sublingual adminstration differ? I'm looking for something that hits me harder than sniffing primarily, as being so similar in effect to ketamine I forgetfully end up doing more than I intend at times on account of the long(er) come up. Thanks.

Thou
 
The synergy between MXE and opiates (in this case H) is extremely profound for me. I've only been using H nasally, and at this point I take around 20-25mg to get the feeling I want from it alone. With a small dose of MXE (maybe 10 to 20mg) I only need 5-8mg of H nasally to get the same effect.

At this point I would say I only use H and MXE together, usually at a ratio of 3:1. For example, at this very moment I'm about to snort 27mg of MXE and 9mg of heroin mixed together.

Sweet dreams everybody.%)
 
The same can be said of quite a few other nmda antagonists, dxm and ketamine among them.

I firmly believe memantine have the same characteristics, only without the dissociative effects. There's a great thread in ADD about reducing tolerance to damn near everything with small doses of dissociatives administered daily with your drug of choice, I'll try to find a link.
 
On the opiate/opioid combos - I used to mix MXE with o-desmethyltramadol on a regular basis in full doses and loved it, never had any problems.

I have also mixed MXE with 3-MeO-PCP and Ketamine to great success. Once on this combo (Ket) I was concerned that my breathing was affected. I felt like the air had turned into tar, moving and breathing was difficult. But this only happened once and I survived. I think it was probably a perceptual thing rather than an actual physical threat to health (but who knows).

I have recently been on a course of 20mg/day Fluoxetine (Prozac). I have taken MXE concurrently without any problems.
 
Thou, before you try rectal or sublingual dosing, I would try oral. I have found it to be superior to intranasal in almost every way.
 
I'm experimenting with 4-FA + MXE + 30mg methadone (daily dose). If I had my 25I-NBOME in solution I might try a threshold dose of that with it, but I dont sadly.

I'm pissed for some reason my parents (no idea why) took my pramipexole bottle with half the tabs left in it. Makes no sense why they would take it, that and my l-atropine. This was a wihle ago, but still fucked up. I was going to save the pramipexole for times i have MXE. The scariest and most out of this world trips on MXE was the combo with pramipexole. Oh well, maybe one of these days I'll get some more in my possesion and have it around for some investigatory use.
 
DroneLore said:
And what about MXE and DXM? Is that just the doubling up of NMDAAs? There are few posts in this thread where individuals have mixed the two and lived to tell the tale. I'm not doubting that it's unsafe, I just want to know why. In fact, I think the rationale behind why each drug is in a given category should be given, so that people can take that information and apply it to other drugs that may not be explicitly listed here.
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This, there's lots of reports of people combining and having moderate to awesome trips on it. Can someone shed some light on why this combination could be harmful? Because I'm a old DXM hardhead and have some MXE and after reading about the combo, I'm very tempted, these are my favorite two drugs.
 
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