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Dissociatives [Methoxetamine Subthread] Combinations - 2nd experiment

bluedolphin said:
"Any info on this with 4 MEC? "

You are going to stress out your heart, raise your blood pressure, and possibly get too dizzy. I wouldn't suggest it. Try them separately.
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I did 4-mec+MXE and a little bit of coke as well just about a month ago, after a fair amount of drinking and a blunt.

I dosed MXE before the 4-mec, probably about 35mg, then did about 60mg of 4-MEC, and then another 50mg of 4-MEC mixed with a relatively equal amount of coke.

To be honest, I kind of like the MXE+stimulant combo, as MXE often makes me unresponsive in social situations, whereas adding 4-mec/coke makes definitely makes me more talkative.

Didn't experience any real notable negatives from the combo, except that I was grinding my teeth like crazy. That being said, 4-MEC is a pretty average stimulant so there wasn't much synergy to speak of either. Give it a shot if you're already on MXE and out at a party or something, but I'd say keep the doses for both relatively low. It wasn't unpleasant per se, but I would only combine MXE in high doses when I'm by myself.

I've never m-holed with 4-mec.

I dropped 2 tabs of acid, ate about 200mg of molly and then railed 120mg of MXE, which started out wonderful, but then I walked into some kind of existential chasm on the way to my friend's apartment. Wasn't unpleasant per se, but I personally don't think I'll ever use high doses of MXE in social situations again. It's just awkward trying to interact with people with that much going on in your head and body.
 
How about Zopiclone + MXE? Anybody tried?

I have tried small amounts of Z with 4-HO-MET and it boosted the visuals to a new level. Z by itself usually causes minor distortions in the visual field, some people may even experience real hallucinations (like with Zolpidem). Due to its sedative properties I suspect Zopiclone dulled the psychological effects of 4-HO-MET to some extent.. but the eye candy was lush.
 
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50mg of mxe with 15mg of 2c-e gave me one of my strongest expereiences ever, this was insane and i felt like i had godly powers that night.
 
Confield said:
How about Zopiclone + MXE? Anybody tried?
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Ok, this was interesting. Had consumed 3 x 7,5mg zopiclone tablets (maybe 2 might have done it but fuck, zopiclone and zolpidem are hands down the most MOREISH drugs I've ever taken, MXE aint got shit on them on that aspect...) then dosed 20 mg MXE followed by another 20 mg some time later. I don't normally see very much CEV's on MXE, actually that 40 mg would normally just make me, well, happy and calm - waiting to dose more up to ~100mg total (even then the CEV's would be almost non-existent).

But with zopiclone I had like 100x enhancement on CEV's. Very trippy shit, 3-dimensional figures handing me presents etc. Due to zopiclone's slightly deliriant kind of properties I sometimes forgot what was going on and interacted with these strange entities like people usually do on Ambien binges and such. I locked myself in my small bathroom with no lights on, sat on the floor and just enjoeyd all the ever changing patterns and limited variety of colors I was able to see. The design of my shower curtain was moving and looking through it I saw some kind of garden or greenhouse with beautiful plants. Altered sense of space was also noted.. The tiny bathroom extended into a much larger space, which on occasion felt like part of some street fair in Turkey or Africa with people selling jewelry and shit. I also observed myself in the mirror and wacky shit emerged. Fun night...
 
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Just tried 2c-b with mxe for the first time yesterday. Really good combo. Didn't think it'd be able to compare with 2c-b and ketamine but I think mxe lended itself better to the trip overall. IV'd 40mg mxe and 3-4mg 2c-b, then 2-3 hours later IV'd 5mg 2c-b and 50mg mxe. Very nice visuals and mindset... mxe seemed to take any bodyload away from the 2c-b (although it could have been that I IV'd 2c-b before, as I'd only taken it orally/nasally before) and the 2c-b seemed to alleviate any of the wobbly-ness, loss of motor skills and slurring of speech I usually get with higher doses of mxe.
 
30mg MXE insufflated, and 30mg 2C-C orally: taken simultaneously. The timing was actually good, with the 2C-C hitting me only a bit more slowly than the MXE.

When I take MXE on its own (well, with weed always), I typically take a dose of either 30 or 40 mg, insufflated, and this always gives me a speedy psychedelic, uplifting and enthusiastic high. In this trial I found the 2C-C somewhat sedating, seemingly overpowering the generally energetic and stimulatory effects I get from MXE. During the come up I was ready to go to sleep. However, in full swing, I found the two together (combined with lots of weed) to be an extremely satisfying experience, though not strong enough for me (next time I'll try 50 and 50 to start). Interestingly, I had almost zero stomach discomfort, which is rare for me when psychedelics are involved. MXE never gives me any trouble, but all 2C-chemicals seem to make me pretty nauseous and give me stomach cramps. I wonder if the MXE somehow smoothed things out there.

I was smoking weed outside in my back yard, but was planning to go back inside... There were helicopters overhead (you might have seen in the news, we're in the midst of student protests here in Montreal). I ended up just listening to the helicopters and nighttime street sounds for about three hours (from 10PM till 1AM), before finally going to bed. It was quite an experience. I meditated sporadically throughout and felt as though I was planted in the earth like a tree. The sounds of the helicopters were at once oppressive and empowering. The responsibility that comes with being a man (a hu-man, that is) permeated every sensation. The wind kept taking me away. I experienced the wilderness downtown.

I dosed at 8:30PM, peaked at 10:30PM and was asleep before 2AM, so under six hours in total. Good, contained stuff.
 
Have you tried oral MXE? I get a lot more bang for my buck that way than I do snorting it.
 
Maybe I should try again, but I've tried oral and sublingual, and finally settled on insufflated as having the best effects for me... Maybe that's because I didn't eat on an empty stomach...
 
Cefuroxime and mxe

Okay. I think i'll leave it anyway.
But if the majority says that this combination seems safe..which i don't expect....i might do it.

Cefuroximes interacts with
Birth controll pills
Medications to lower stomach acids
Oral typhoid vaccine
Probenecid
Diuretics

The only thing that's concerning me is diuretics, because mxe dehydrates pretty strong and is obiusly not easy on kidneys.

And by plugging i should avoid any liver problems, right?

Oh and i am not taking the antibiotic for something major.


Please merge with mxe combination thread.
I am just looking for an fast anwer. sorry.
 
It's not listed as being contraindicated with ketamine, aside from that I can't say.

And by plugging i should avoid any liver problems, right?
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Sorry, plugging (and other non-oral ROAs) merely lets the drug get to your brain and act without being subject to first pass metabolism. If it's hepatically metabolized it'll still be hepatically metabolized.
 
Thanks for your reply.
Even if it might seem safe..i'll leave it.
Not worth the risk.
I'll just eat something and go to sleep.

Cheers
 
I was wondering about certain supplements interacting with MXE, ones like 5-HTP, L-Tyrosine, Niacin, among other neuro-chemical precursors... Could peak blood concentration levels of these supplements somehow interact negatively with MXE? Anyone have any experience or input on this?
 
Ive read many varied opinions on MDMA + MXE. Could mxe safely and enjoyably be taken in a rave setting at the tailend/comedown of pure mdma in order to sidestep the comedown for a few hours until I am home?
 
like you said there are varied opinions.
in some cases it went good and in some not.
so there is the chance of having a very bad reaction.

the fact that people had bad reactions from this combo would put me off.
better safe than sorry. ^^
 
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Hello.
Can somebody tell a few words about your experience combination of two - MXE and 3 meo-pcp ?

Thank you in advance.
 
Quick question, would MXE taken tonight effect effect how hard I roll on MDMA in four days?

MXE tonight - Pure MDMA and possibly 4FA four days later

Is this likely to effect how hard I roll? Is there a cross tolerance? Should I just wait? Or is this ample time?

thanks
 
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rkline said:
Quick question, would MXE taken tonight effect effect how hard I roll on MDMA in four days?

MXE tonight - Pure MDMA and possibly 4FA four days later

Is this likely to effect how hard I roll? Is there a cross tolerance? Should I just wait? Or is this ample time?

thanks
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I would not expect any cross-tolerance between the two. You're good to go. :)
 
I read in the DXM FAQ that NMDA antagonists shouldn't be combined with alpha-2 adrenergic antagonists like Yohimbe due to concerns of greatly increased neurotoxicity. First, does anyone know if this is accurate? If it is, this should probably mean that Kratom, with its alpha-2 adrenergic action, should not be mixed with MXE due to increased neurotoxicity concerns.
 
I can report a pleasant interaction between Paroxetine and MXE (20mg). No negative effects, though I do guess the high blood pressure effects stack.
 
Hello.

Can someone please tell about the combination of two : MXE+3-MeO-PCP.
Thank you in advance!
 
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