I see Tramadol and other general opiates have been listed separately, can we assume that combining MXE and O-Desmethyltramadol carries the same risks as MXE and standard Tramadol (on top of the respiratory depression risks associated with mixing various downers)?
I don't know, but ~40mg O-DT + low dose MXE was quite pleasant for me. I think there was another user here who's combined these two regularly.