I'd have to agree, Pink Flamingos is the most disgusting movie I've ever seen, although Waters came close with Female Trouble and Desperate Living.
One time in college we rented all three and watched them as a John Waters Film Festival trilogy in our dorm suite. We had invited some females over on the bogus premise that we were hosting an artsy film screening and 3 had shown up...unfortunately, by the time we got halfway through Pink Flamingos they had all left in disgust.
Apparently they just had no sense of humor.
And I wonder why I rarely got laid in college.