<<yeah. i think a lot has to do with why one partakes. i've read that people who are in real serious pain do not get addicted to opiate pain killers. they just experience relief.>>
People with chronic pain are less likely to become psychologically addicted to opiates, so generally develop a tolerance slower and consequently have far less severe (controlled) withdrawals if they come off them/don't need them anymore. They still become addicted.
<<i've read that the fellow who developed this molecule had his hand blown off in the serbian war as a child. grew up to be a chemist. as someone who recently lost use of an arm and is in never ending nerve pain i view his creation as a godsend. it's all a matter of perspective. marketing? who gives a flying f*ck? if it works. if it is a cure. then so be it. people need to understand that not everyone approaches any molecule from the same angle that they personally do.>>
Its effectiveness in dealing with serious neuropathic pain, for instance losing a limb probably derives mainly from its NMDA antagonism- racemic methadone (dextromethadone is an NMDA antagonist), levorphanol, pethidine and other synthetic opiates plus, obviously, ketamine could provide similar relief within a clinical context. I don't think using a completely untested RC long-term for a genuine pain condition is sensible. It may be a cure for now, but I seriously doubt it is sustainable- even if it remains available for another 3-5 years, then what- you're 5 years down the track, your condition is probably worse and there's every chance that you'll cause yourself problems with the doctors down the line when you
need more real drugs than they'll give you because your medical history has been distorted by MXE usage. Besides, the rate at which most peoples dosages increase/people accumulate a tolerance would indicate that it it loses its efficacy relatively quickly.
In addition, as it is a dissociative not an analgesic, methoxetamine causes profound personality changes that can become 'integrated' into your general perception. Read through these threads with a critical eye- there is a lot of delusional rationalisations of obvious drug abuse, look at the adjectives, look at the meglomania- it's all part of the fun, but when it becomes a part of your everyday outlook you're just a narcisistic fuck.
I understand that not everyone uses methoxetamine for the same reason, I'm mainly trying to spur on some more indepth discussion about our favourite RC.
<<MXE is the best antidepressant I can imagine. Consider using it in 10-20mg insufflated doses, as you won't need more than this for good antidepressant effect. And your friend might be scared away if you give him a fully dissociative dose right off. With no tolerance, certainly 15mg sniffed will put you in a much better mood in less than half an hour, and probably last all day.>>
See, here is where we seem to differ. I suffer from chronic depression and anxiety, I have been diagnosed with a social phobia and Borderline Personality Disorder with Schizoid traits (that's a fucking mouthful). I do not consider myself a schizoid, I am simply misanthropic, however I am absolutely a borderline personality. Consequently I am prescribed a huge amount of medication that I don't take (I'm 'on' bupropion, quetiapine & risperidone), mainly because the side effects are horrific and they don't make me feel better they make me feel like a different flavour of shit and because, to put simply, I don't want to be dependent on drugs. I don't want to have to take an anti-depressant or an anti-psychotic everyday anymore than I want to be hooked on opiates and have to take them every single fucking day.
About 75% of my usage is theraputic, however I don't use methoxetamine as a anti-depressant in the sense of exploiting its mood lifting characteristics, instead I will have a particular problem/question that will be the 'focus' of my trip, I will then plug 50mg (with another 25mg ready to go, if I feel I need a booster) and meditate on my 'theme' until the drugs take effect and start guiding my minds thoughts. In particular relationship to BPD methoxetamine allows me to properly reflect on my emotional state and, essentially, how I feel about my feelings which allows me to overcome 'splitting', which is one of the major psychological mechanisms of BPD (basically I will alternately over-value then under-value people without integrating my contradictory feelings into a balanced perspective, black/white thinking). Methoxetamine is my metaphysical therapist, it provides me with theraputic experiences that give me a greater understanding of myself and how I should/can relate to the world and others.
My decade of suicidal idealisation (triggered by being left on high dose prozac while an teenager for years despite me complaining of suicidal idealisation) was cured by a single 1200mg dose of DXM, objectively speaking it was one of the most unpleasant experiences of my life, but once I was sober again I was a completely different person. I accepted my mental illness (rather than everything being others fault), stopped wanting/trying to kill myself, started going to therapy, returned to university, proposed to the woman I love, started eating properly...this sort of experience, along with other experiences I have had with methoxetamine, ketamine, 4-meo-pcp and nitrous oxide is what makes me think that there is real hope for dissociative-based therapy in the future, however I think that it will/should take the form of the Ketamine Psychedelic Therapy carried out in Russia- 'process orientated' high dose sessions in combination with therapy, not day to day dosing. Dissociatives are simply so personality altering I can't see extended usage being that great for the treatment of mental illness, even if they do effectively combat its symptoms. The way people talk about it worries me a little, imo the drug itself is worthless, the experience of the drug can be profoundly theraputic.
<<I disagree with saying its unlike ketamine... I have found it to be very similar... more spiritual if anything... its just not as fast coming on and dropping off... I've been experimenting extensively on myself as well as willing and right minded individuals... as well as a couple of unknowing/uncooperative/distressed individuals...>>
What does 'spiritual' mean? I read it to mean 'more likely to cause delusional thinking', which I enjoy greatly. When I say it's not like ketamine I'm not simply talking about the come-up/duration I'm talking about the whole experience- ketamine is quite structured in its effects, once you're familiar with its arc you can sort of orientate yourself within the experience, no matter how crazy it may be. Methoxetamine is more 'free form', each experience has its own course and flavour. Ketamine is more like an opiate (does what it does in the order that it does it for as long as it does it) while Methoxetamine is more like acid trip, if you see what I mean? It goes where it goes, shows you what it's going to show you, and spits you out as it sees fit. From my experience with 4-meo-pcp and what I have read about pcp/pce methoxetamine seems a lot closer to this end of the arylcyclohexamine family.
And I hope you atleast babysat the 'unknowing, uncooperative & distressed' individuals
<<The only real differences seem to be that mxe is richer and warmer and doesn't incapacitate people the way ketamine does...>>
This I agree with, I love ketamine, I love its analytical edge, the slightly mechanical, inhuman feeling it has; but methoxetamine has the richness and depth of traditional psychedelics without the unpleasantly alert feeling that I have grown tired of.
I have seen (mainly inexperienced) people be so overwhelmed that they've closed their eyes and not moved for 4-5 hours. Once I was actually kinda worried at the time, as far as I knew (this was before I tried plugging and unlocked the m-hole) you shouldn't hole- kept secretly worrying that he had OD and we hadn;t noticed, even though he was sitting right next to us, even though I could see he was breathing and I asked him if he was still feeling fine and if he wanted some water or anything every 15 minutes. He had his eyes closed with a huge grin on his face for like 5 hours before I left, may well have stayed in that same position another 5 hours for all I know...
<<While its easier with ketamine it is possible to achieve a hole with MXE, it just requires obscene doses.>>
If you don't have a ketamine/general NMDA anatagonist tolerance this is not the case (depending on your physiology)- when I started experimenting with MXE I hadn't taken DXM for around 8-10 months or ketamine for about 3 years and I found it easy to hole with doses of 50mg+ plugged. I have, however, found it almost completely impossible to truely hole from any other ROA (though I haven't tried IM)- after the peak had passed and I was back in my body from plugging 80mg (about 3.5 hours in) I felt roughly as high as I felt after snorting 200mg (4 50mg doses over about 2 hours).
I'm sorry for this obscenely huge post, I've been lacking in people to shoot the shit about the MXE over the last sixth months... To end, a question- what are the dosage comparisions between plugging and IM? I haven't IM any yet, but the mechanics won't be a problem as my partner is a nurse, I've just been putting it off because I've been worried about either underdosing and getting cocky/being dissapointed or overdosing and having a little too intense of a trip. I want a strong M-hole experience, for me this works out to be about 80-100mg plugged- how much should I be looking to IM?