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☛ Official ☚ The Big & Dandy DOC Thread - Third opinion

Alright thanks !
Sounds riscy imo, DOC is already quite hard on the vasoconstriction.
Quite deadly at not super high doses.

I wouldnt mix it with anything outside of other psychedelics that are very safe or dissios like Ketamine (awesome combo btw).
Guess i'll add ALLAD and 2cb then. Ketamine i only do at home to come down with a movie or two 😉
 
Did anyone ever try 2-3mg of DOC with 5mapb after lets say 6hours? Ideas ?
Shulgin reported the combination of a 5-HT2A agonist with α2-adrenergic & imidazoline-1 agonism to produce entactogenic effects. He used 2C-B-FLY with rilmenidine (reduces BP) but agmatine is a fair otc alternative with its own psychoactive properties (α2-adrenergic & imidazoline-1 agonist, NMDA antagonist, sigma-1 agonist).

Sounds riscy imo, DOC is already quite hard on the vasoconstriction.
With these vasoconstors its probably a good idea to have niacin (nicotinic acid) on hand. It's a fairly potent fast acting vasodilator.
 
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