That was my understanding until short ago but apparently that's not clear, supposedly some psychedelics like DMT or 5-MeO-DMT don't have cross tolerance with other psychedelics, at least according to Psychonautwiki and some reports. Not have personal experience mixing those with other psychedelics, just this last time. So I don't know what to think. As well, I just kind of fell asleep during what I considered underwhelming effect, but maybe I blackout and I don't remember...probably not, still...
I don't think I would replicate any other experiment either nasally or plugged at 10mg. But maybe I have the chance to compare higher dosages. But if plugging works well, I might never look behind.
In fact I was inclined to try 20mg plugged with no other psychedelic involved, probably the worst it can happen is a breakthrough, considering that ROA was similar to insuffated. But now you are making me doubt...anxiety can probably be an issue with this one.
On the other hand I don't have plenty of it, and I would like to get a deep understanding of the compound to at least know if I want to purchase more.
It is kind of weird nobody can give us clear info about dosages of plugged 5-MeO-DMT, considering you can avoid the drip...