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Deleted member 81238
Bluelighter
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Plus Br2,
No se requiere ephedrina.
Why not simply obtain L-PAC which is uncontrolled? - you can halogenate that quite simply.
I think a great challenge would be to find a way to produce 4-MA$ from L-PAC in a facile manner. I've spent ages searching with no luck, but it's likely MY limitation rather than a limitation of the chemistry.Smyth2
Bluelighter
If I were you I would be tempted to contact a university and apply for it on your research thesis. Either that or the fluoxetine analogs made from ephedrine. You said Bounce has been made already though and you have tried it? Another leaving group that could be considered are tosylate or triflate groups.
Step 1: PBr3
Step 2: KCN, OH-
Step 3: Cl-TMS (chloro trimethyl silane)
BOUNCE in ONLY 3 STEPS!
Rectify
Bluelighter
Smyth2
Bluelighter
Well Bounce & Fluoxedrine are the only 2 of your ideas that are worth trying IMO. The rest can be discarded.
TRIZAK
1-phenyl-1-(4-trifluoromethylphenoxy)-2-methylaminopropane
Yeah, it's MUCH easier staring from a controlled compound!
Did you even check what L-PAC was?
And a methamphetamine precursor. It's a 1-pot reaction.