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Dissociatives [Methoxetamine Subthread] Combinations - 2nd experiment

Oh my heck, 200mg of 4-FA with approximately 75mg MXE left me dry heaving for like nine hours.. Never again.
 
100mg 4-fa (early afternoon) + 70mg MXE (early afternoon) + 30mg methadone (the morning) + 50mg doxylamine (in the morning) + 2mg clonazepam (in the morning)

Feels great. Just wish I had a cig. Gonna get some work done.
 
I know MXE and bk-MBDB is a dodgy combo, but would it be safe to take a low (27mg insufflated) dose of MXE after (thinking about an hour to half hour after) the comedown of a low (79mg oral) dose of bk-MBDB?

Edit: I also thought I'd add, to contribute some HR information, that at least at low doses, methoxetamine does not interact adversely with levothyroxine (unlike ketamine). I take 100ug of levothyroxine sodium per day, and after light (25 to 50 mg insufflated) MXE use I have not experienced any tachycardia or hypertension, nor have my thyroid levels changed in any unexpected way (yes I got them tested in between my first and second times taking MXE). I don't know why levothyroxine and ketamine interact, but it's a combo that basically all drug interaction databases strongly caution against.
 
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I apologize if I missed this in the thread I saw mention that MXE was not a good mix with MDMA is there because of the serotonin factor or is this experienced because of the poor quality of most pills and therefore the same ill effects as the mix with uppers? Has anyone mixed MXE with MDA? Is MXE acceptable to use like Ketamine with MDA in small doses throughout the night to enhance the effects of the MDMA?
 
Ohagan said:
I apologize if I missed this in the thread I saw mention that MXE was not a good mix with MDMA is there because of the serotonin factor or is this experienced because of the poor quality of most pills and therefore the same ill effects as the mix with uppers? Has anyone mixed MXE with MDA? Is MXE acceptable to use like Ketamine with MDA in small doses throughout the night to enhance the effects of the MDMA?
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I would avoid MXE with MDMA at any dosage as a precaution. I've heard a few reports of people having amazing times though, and if people really want to mix their drugs they're going to mix their drugs lol.

I've read a few times that MXE has serotonin reuptake inhibiting properties, that mixed with a serotonin releasing chemical like MDMA could put you at risk for serotonin syndrome. Its nasty, i've had it a few times. Nausea, long lasting headache, aches and pains. Try to avoid it. Other than that, the main concern would be hypertension, tachycardia, and overall stress on the body. Stay safe
 
Thou said:
Been using MXE and 2c-P both insufflated in moderate doses with great success.

I found 2c-P (8mg insufflated with a bit of tolerance) alone to be rather boring, but 20mg bumps [of methoxetamine] every half hour or so until you reach a place where the profundity can't be ignored. Total ego death, absolute beauty.

MXE and small doses of suboxone seemed neutral and I don't generally use opiates, just a bit of suboxone at the end of the month when my 3mg klonopin reserves are down to a minimum, usually .25mg.

MXE and neurontin didn't feel like they potentiated one another all that much, but no negative effects were observed.

MXE and 5meomipt blurred the effects of the 5meo to the point where I couldn't rightly feel the 7mg 5meo. I had never taken the moxy beforehand and took it at the tail end of an MXE session (24 hours), but the effects were much more pleasurable and "mushroomish" than the MXE alone.

MXE and mindfulness meditation at the peak of the "hole" or however you'd phrase the pinnacle of the experience were a godsend. Listening to Thich Nhat Hahn leading a meditation on transience audio file was mindblowing after I found myself taken aback and hit hard with TOO much of the MXE, the afterglow lasted a full 10 hours until sleep was observed.

All of my experiments were with insufflated MXE. Does anyone know how rectal and/or sublingual adminstration differ? I'm looking for something that hits me harder than sniffing primarily, as being so similar in effect to ketamine I forgetfully end up doing more than I intend at times on account of the long(er) come up. Thanks.

Thou
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Rectal hits faster than sublingual to me. I don't like insulfating, makes it more speedy and shortlived with a quick drop off.

Sublingual usually takes 30-45 minutes to hit for me, rectal ~15. Start feeling "something" after about five minutes or so, then it just hits full on pretty quickly. It can be somewhat overwhelming on a higher dose though. I would advice to be situated nicely and don't fight it. I've made the mistake of dosing rectal, and still trying to roll a joint, or take a shower, or "Get ready" so to speak, and it hits in the middle and I'm fucked.
 
mxe and 2c-c synergize so beautifully.So much euphoria. A super euphoric, visual, controllable type "hole". Mmmm mmm good. I like to mix equal amounts in one solution. Usually ~50mg of each to start with, with another redose of the same. Taking all at once is very overwhelming, especially the comeup.

mxe and dpt. So fucking sexy. Want nothing more than to just lay down and feel goooood. Watch out though, this one has a lil sinister edge lurking under the surface IMO.
 
I've found equal doses of 2C-C and MXE taken simultaneously to produce less visuals than that dose of 2C-C taken alone.
 
mxe + 5-meo-dmt was quite confusing for me, i just remember being in a different world for some time hoping the 5-meo-dmt would just wear off as soon as possible.

Not too bad of a combo though, i would like to experiment again soon.
 
MXE after Methadone
Rrrreally nice. Nod and euphoria. Much better than the methadone alone (I'm not on maintenance).

MXE after Kratom
Intense (uncomfortable) serotonin. Need to scale back dosage next time.

MXE after a 4-FA binge
Onset felt like my heart was about to shit the bed (wild palpitations). Panicked, did not mix well.

MXE + Gabapentin
Smooth and relaxing. The gabapentin mutes the 'trippiness' but I still get the immersion/fascination and mood boost from the MXE. If you dislike the mania of MXE, you will probably enjoy this combo.
 
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Are there any contraindications between DXM and MXE? It seems potentially unsafe, because DXM inhibits serotonin reuptake, and some really nasty interaction has been reported between MXE and triple release agents like 6-APB. On the other hand, I'm pretty sure psood0nym here has described pretty interesting and overall positive experiences combining DXM and MXE.
 
TheAppleCore said:
Are there any contraindications between DXM and MXE? It seems potentially unsafe, because DXM inhibits serotonin reuptake, and some really nasty interaction has been reported between MXE and triple release agents like 6-APB. On the other hand, I'm pretty sure psood0nym here has described pretty interesting and overall positive experiences combining DXM and MXE.
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Post #1 in this thread:

Unsafe / (Potentially) Dangerous - due to potentiation or negative interaction

DXM
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Not sure what the specifics are though.

I still don't understand the idea that it's something in the serotonin system that causes some of these interaction issues. I've been taking fluoxetine, an SSRI, and combined it several times with MXE, no problems whatsoever.
 
"Any info on this with 4 MEC? "

You are going to stress out your heart, raise your blood pressure, and possibly get too dizzy. I wouldn't suggest it. Try them separately.
 
i recently tried a combo with 120mg of MXE insufflated + 25mg of DMT inhaled + nitrous. lots of euphoria in which my body felt like it was rising, falling, and waving. visuals were astounding and flowed very smoothly prior to the nitrous hit. after the nitrous i noticed the "wobbly" (wah-wah) effect of nitrous take hold of the experience in a visual manner, rather than the usual audio mechanisms it produces with me. it was like a big wobbly glob interrupted the smooth transitional geometric patterns flowing from DMT space and warped them to fit its needs.

i am in the process of sublingually dosing 115mg of MXE and plan to do this combo again in about an hr...anyone else try this?
 
Well, I did 354mg DXM and 15mg IM MXE at T +1:00. It wasn't nearly as fun as expected and felt like serotonin syndrome. I've gotten it once before much worse from doing DXM a day after rolling with out thinking and had seizures, vomiting, general dysphoria for 48 hours. I was about to go to the hospital because of the seizures but as it got the worst, the symptoms began to subside. Never again will I be doing anything that can cause serotonin syndrome even possibly. It wasn't as bad this time, only lasting about 20 hours, but I would advise people to be careful. I was going to do 40mg IM but only did some of it to see if it was plasureable, and I was very glad I did not do more. Relatively boring trip, felt like real life, just talking to people, really weird for the first hour then painful and dysphoric and seizurey.

Did Nitrous and MXE a bit ago though, really strange, not how I thought it would be. I felt like a road. That's the only way to explain it.
 
I honestly had a slightly scarry moment with LSD, mariujana and MXE. TONS of POTENTIATION from all angles.
First time it potentiated the visuals immensly. Body load was fine. My friends and I Could barely communicate though, loopy sentences and just not able to spit out a thought.
second time;
LSD @ 10pm, didnt smoke any weed, had a decent amount of beers. Did the MXE at around 5am. and then taking two bong rips an hour or 2 later, put me out, and brought back the high more than ive ever experienced. skecty palpitations and body load, felt like i had a brick in my chest and at points my body would seize up if i tried to lay down, not a very comfortable state, lots of synergy... i attributed it to not listening to my body and probably was dehydrated... Could be different for everyone. but PLAY IT SAFE please. This just makes me feel reckless.

HONESTLY imo i see people get fucked on this shit every weekend and i hate it. It makes them dumber than a blackout drunkard and half the time no one can walk or talk properly. Lots of ppl are abusing it i find and that turns me off... also people just get SO OUT OF IT when they do it doesnt look cool. Know your dosage .

PS: My friend and i have Nicknamed it "THE STRANGE" for obvious reasons and that name has stuck around for the most part on the scene. funny how that works :)
 
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