mephedrone long term negative effects progress reports

[Xamkou]

I hate the cold hands/feet side-effect. It's going to be problematic this winter!

 

[PandorasBox]

Its a couple months later- and I am feeling much better. I've actually forgotten about the post on the previous page. I still occasionally worry about my heart- but I don't know that its any different than its always been. A few things are different- Im much more sensitive to the sympathetic side effects of stimulants now. I had to cut my daily amphetamine dose in half- which is strange and worth noting. Suggests some sort of long term change. I still worry ab what kind of long term damage I did to my brain- but I think the biggest thing I was experiencing at that time was normal worry about what an unknown chem did to my body and most importantly anxiety and paranoia precipitated by the drug.
That created a feedback loop of negative, occasionally irrational thoughts. So, I think to others- its definitely worth noting the anxiety and paranoia that follow binges, and how destructive they can be to your mental health.

Interestingly- I started taking bupropion (for its lesser stimulant effect and treatment of ADHD), and I noticed that its a cathinone analogue. That means that some drug company somewhere probably has a library of data on a whole library of cathinone analogues. I would love to get my hands on that. I used to work for a small drug company in drug discovery- and I remember going over those animal study reports and trying to figure out a way to justify moving it to human trials.

 

[EFC18]

Psychological problems are unavoidable with heavy usage, it has all finally caught up with me. Decreasing purity, increasing tolerance and other factors have contributed to it now becoming a wholly unsatisfying experience.

Fuck it.

 

[ColtDan]

^ agreed. the meph down here is now absolutely bollocks. ive given up trying to find any decent stuff now, few people i know who havent been doing meph long keep railing the shit stuff thinking its good, and im just like, this stuff is bollocks. complete waste of time

I hate the cold hands/feet side-effect. It's going to be problematic this winter!

it is. i work in a big warehouse full of steel, it reaches -10 sometimes in the winter. ive experienced all the numb hands/pins and needles/red fingers/cold hands side effects and i had the side effects quite bad last winter from doing meph quite a lot. combine this with working in very cold conditions all day it makes your fingers feel feeling horrible, my fingers started to hurt pretty badly

 

[mark87]

i was taking mephedrone once a week every week but started getting really bad comedowns. i've now not taken it or any other drug for about 5 weeks and still my head doesn't feel right.

i used to be happy and enjoy life but now i feel depressed, miserable, confused, forgetful, less able (physically and mentally) and paranoid. i have little to no self worth or confidence. my brain feels cloudy and dumb. i've lost all feeling and emotion and no longer enjoy things i used to. i'm seriously worried these effects may be permanent.

what should i do?

thanks

 

[brandy42]

I'm not sure if this is helpful or not.

But I will say that I was taking mephedrone 3 times a week for six months (Dec 09 to June 10).

I stopped taking it because if found myself sitting up for 20 hours or more.

Coincedentally after stopping it I started posting on Bluelight.

If you read my posts, around July 2010 that will give some idea of the strangeness.

I would suggest you stop it now.

 

[wrxya33]

Well this is certainly interesting and important information. This could potentially be clear evidence that Mephedrone is toxic even in small quantities. We need more BP readings from people who use this stuff.

6-8 grams of mephedrone in a 2 week period is not a small quantity. Especially since he did this amount in only 3 sessions. So thats a minimum of 2 grams a session. Thats a huge amount.

I just started doing mephedrone about 2 months ago and im on my 4th gram ever and i normally do 400-600mg over a 12 hour period. I have had zero issues other then normal stimulant anxiety and edginess when im coming down.

 

[theotherside]

^^Trust me, if you really start using mephedrone 2 grams in a session is normal I started out a year ago thinking, "Wow what a wonderful substance, I only need 500mg's a night"...fast forward a year later and it has made my g'/f and I fight when we couldn't get any one weekend. We are lucky to do less than 5 grams between the two of us in a weekend session. We almost always have to combine with it with other cathinones to get the same high.One of the greatest highs of all time but also a terrible drug(up there with coke although not as addicting physically).

 

[MeDieViL]

Probably however the fact that effects persist for months indicates there's more at work than just simple vasoconstriction.

I would gues the metabolite somehow upregulates the alpha adrenergic receptors leading to increased sensivity to vasoconstriction caused by other stimulants, im just figuring out i may have gotten this issue last summer with flephedrone, however i didnt have any issue for months since i was taking cardiovascular meds to block amphetamine induced anxiety lately i ran out of them and started getting those symptons again, i first didnt know what was going on untill after a few times a took a big dose of amphetamine and turned purple, get severe chestpains, severely fast heartrate etc, then i started looking at my veines and fist didnt find them, then suddenly saw they looked like the smallest wires i ever saw immediatly knew what was going on, i even had 2 spots on my skin turning grey but i was right in time, i took some aspirin, nac and viagra with diluted my veins quite a bit, viagra works in the coronary veins, but its mostly selective.

After that i restarted my supplement curcumin with my arb blocker candesartan and the problem has immediatly cleared up, both have vasodilative effects, just like anyone posted here before, i couldnt even take normal doses of dexedrine anymore, they felt extremely unpleasant, wich i first didnt connect with severe vasoconstriction.

Without stimulants i dont have any issue feel completely normal, but i seem to have gotten a ton more sensitive to the vasoconstrictive effect of stims.

That said i would highly suggest caution by adding cardiovascular meds, its still unclear what causes the long term increased sensivity to vasonstriction.

 

[pofacedhoe]

^^Trust me, if you really start using mephedrone 2 grams in a session is normal I started out a year ago thinking, "Wow what a wonderful substance, I only need 500mg's a night"...fast forward a year later and it has made my g'/f and I fight when we couldn't get any one weekend. We are lucky to do less than 5 grams between the two of us in a weekend session. We almost always have to combine with it with other cathinones to get the same high.One of the greatest highs of all time but also a terrible drug(up there with coke although not as addicting physically).

its way more addictive than cocaine, i can stop taking coke in a binge with a bit of effort but with mephedrone its almost impossible and you end up going for days.

i wont touch that dirty shit now

 

[vortex30]

^^Trust me, if you really start using mephedrone 2 grams in a session is normal I started out a year ago thinking, "Wow what a wonderful substance, I only need 500mg's a night"...fast forward a year later and it has made my g'/f and I fight when we couldn't get any one weekend. We are lucky to do less than 5 grams between the two of us in a weekend session. We almost always have to combine with it with other cathinones to get the same high.One of the greatest highs of all time but also a terrible drug(up there with coke although not as addicting physically).

Neither one is physically addictive. I must say Mephedrone has caused me way more serious side-effects and addictional challenges than cocaine, but that may mostly come down to price. I'm over 7 months off the stuff now. After 16 months of using it at least once a week, at least a gram in a session, usually binging for 2-4 days for 5 months of that period.

 

[melange]

ok I feel like an idiot because everyone on here, knows that I have a little common sense

I got 250mg of very pure meph recently(this is my only second time doing it)


I have adhd, and stims affect me very differently than most people

I barely did half of the 250mg in a night and my heart rate was pounding hard(but I already have a panic disorder) - the tachycardia felt no different than from when I smoke really good weed(in fact I have had weed skyrocket my hr to 180)

so to be safe, I went to the emergency room, and got a script for xanax

now they did ekg's chest xrays, blood work, all the shit and said I was fine(ruled it out as axiety/panic attacks, since my vitals weren't too bad - like heart rate 120-135, bp was like 135/90, so nothing serious

I am asking if xanax would be useful If I wanted to do the rest(don't have much left;meph that is); I assume it would help greatly

I am really sensitive to stims, I hear all these people doing fucking grams and grams in a night, which like I said earlier in this thread, was the real culprit behind the negative side effects, overdoing it

I mean this 250 lasted me like 3 days

but like I said I am sensitive to stims(because of anxiety problems)

 

[melange]

oh and just for the record, I have usually always made it a rule of thumb to never do stims without some depressant near by(preferably opiates or alcohol)


I even have a shitload of trazodone and tegretol if I need it

 

[melange]

if i ever do stims again(not very often) i wanna have atenelol/clonidine/amyl nitrite/aspirin nearby


that is just because I am a scientist/health nerd


and I know a lot about medicine and healthcare

shit, I am such a hypochondriac, might aswell have some sodium nitroprusside



hypertensive crisis's do not sound fun

 

[pr0d1gy]

if i ever do stims again(not very often) i wanna have atenelol/clonidine/amyl nitrite/aspirin nearby


that is just because I am a scientist/health nerd


and I know a lot about medicine and healthcare

shit, I am such a hypochondriac, might aswell have some sodium nitroprusside



hypertensive crisis's do not sound fun

I think that people self administrating Beta blockers and vasodialators (especially ones as strong as SNP) is a bad idea. Mixing certain beta blockers with mephedrone could cause vasospasms. If the vasoconstricitve side effects from mephedrone use are so strong you feel that you need a beta blocker or especially SNP, you should be in the ER.

 

[pofacedhoe]

if you have a panic disorder dont take mephedrone

 

[Elieseweiland]

I need to strongly caution anyone using to stop as soon as possible.
once you start... its a hard habit to break
it gets worse trust me...
I'm only a week sober so I'm not sure yet what all of my medical issues are going to be but I can tell I have a long road ahead of me.
If anyone wants to seriously talk about their addiction I offer my support to you.
symptoms:
-vomiting blood
-shortness of breath
-abnormal heartbeat
-loss of feeling to certain parts of my body
-excessive weight loss (over 20 pounds in one month)
-cant tell when i'm hungry or when I get full (really not sure what this is about would appreciate any insight)
-loss of empathy (think thats the right word but basically I get confused when people express emotion, I cant tell emotions apart all the time)
-Paranoia
-aggression

and man thats just the tip of the ice berg it seems... I didnt list most of my mental symptoms cause its just too much. I have never had issues with addiction before.. I didnt even really like doing drugs. thats why this drug is so scary... if you dont have limits you wont stop... I was using roughly a gram a day... every day for a month at the end. Even with all the health issues I would talk myself into it being ok.

Please use me as an example I need everyone to know how dangerous it is!!

 

[sackynut]

Ill add my two cents I guess. This stuff is nasty. I got it from a very reputable source and binged for 3 days straight on two separate occasions. The first time wasnt as bad, but the second....but the end my lungs felt like someone was sitting on them. My heart still hurts after a few days sober, my body aches, and I cant tell when Im hungry or full either. But at the same time Im losing weight. Definitely am not going to fuck with this stuff anymore.

 

[melange]

amphetamine is better imo

 

[Lady Codone]

I'm trying a one month on, one month off thing with mephedrone right now after going through 3 grams in December. (January is my "off" month). My most terrifying side effects were nosebleeds that would leave me so dizzy and nauseous I blacked out temporarily. And then I learned to crush the little crystals before snorting, which helped immensely. (Meph is the only thing I've snorted so it didn't occur to me).

Seems like a lot of the more frightening side effects I see are with people who completely binged out beyond what could ever be considered moderate. Are there any stories of severe side effects with low-to-medium doses (no more than a gram per week)?