mephedrone long term negative effects progress reports

[Coolio]

A big order coming through? You make it sound as though it's still legal and can be bought online.

You make it sound as though only legal things can be bought online; or as though only product sold via the internet would come through as a shipment.

 

[psychenaut87]

So without bullshitting anyone since that wont help me find answers heres my problem. I recently had an extremely large amount of mephedrone and proceeded to binge on it like it was coke. yes this is a stupid thing but for about a week i was blowing at least a gram a day and that was a small amount if only limited to a gram. i stopped as of yesterday and have had extreme paranoia, a light headed tingly sort of electric shock through face and hands, can feel heart beat through chest without touching and other bad heart and body sensations. does anyone know what i could potentially have? can time solve these problems or should i seek immediate medical help?

 

[vortex30]

So without bullshitting anyone since that wont help me find answers heres my problem. I recently had an extremely large amount of mephedrone and proceeded to binge on it like it was coke. yes this is a stupid thing but for about a week i was blowing at least a gram a day and that was a small amount if only limited to a gram. i stopped as of yesterday and have had extreme paranoia, a light headed tingly sort of electric shock through face and hands, can feel heart beat through chest without touching and other bad heart and body sensations. does anyone know what i could potentially have? can time solve these problems or should i seek immediate medical help?

Sounds like a normal reaction to a heavy mephedrone binge to me. Keep off the stuff a few more days, eat well and hydrate and sleep lots. You'll be alright, can tell you I've been in a similar state at least 15-20 times in the past year and at the moment I'm 2 months off the meph, I feel back to normal health just about I'd say.

 

[MikeHawk]

So without bullshitting anyone since that wont help me find answers heres my problem. I recently had an extremely large amount of mephedrone and proceeded to binge on it like it was coke. yes this is a stupid thing but for about a week i was blowing at least a gram a day and that was a small amount if only limited to a gram. i stopped as of yesterday and have had extreme paranoia, a light headed tingly sort of electric shock through face and hands, can feel heart beat through chest without touching and other bad heart and body sensations. does anyone know what i could potentially have? can time solve these problems or should i seek immediate medical help?

Wowza. You should be fine but I recommend being careful over the next few days. I also recommend using some l-tyrosine as that's been shown to relieve a lot of the symptoms of Mephedrone withdrawal.

 

[ColtDan]

ok i did meph a week ago...and i just drank some alcohol and noticed my left kneecap has turned a bit red/blue with some cold feelings in my feet. what the fuck. i also noticed i woke up earlier with pins and needles in my hands, etc. nasty stuff i need to stop doing it. this isnt the first time ive had numb feet/hands and pins and needles etc.

 

[EFC18]

Extreme light headedness when sitting up quickly; vision blurs head feels numb
sharp black "swirls" almost, moving at high speeds in my vision
changes to smell of urine


apparently both these are indicators of hypotension (low blood pressure) and normally plague me the day after larger sessions. Anything to this?


Also nasal septum has become thinner, nostrils themselves really thin.

 

[pofacedhoe]

Also nasal septum has become thinner, nostrils themselves really thin.

this will be very difficult to tell unless someone else looks up your nose (for holes in the septum), still sounds like you need to cut out the meph

 

[EFC18]

this will be very difficult to tell unless someone else looks up your nose (for holes in the septum), still sounds like you need to cut out the meph

Agree, you have to tilt to an uncomfortable angle for it to be noticeable but it's definitely gone beyond a hypochondriac phase, starting to really feel the affects now.

Right now for example the black swirl things are back. Further evidence (possibly) that blood pressure been raised significantly.

 

[PandorasBox]

enduin-
I have had very similar effects. I've used less than 5 grams over about 7 sessions, one time using a gram and two other times 500 mg. About a week after the last time I started having breathing difficulty and chest pain. I went to the ER and had a full workup and everything came out fine. I have also had palpitations and chest pain frequently over the following two weeks which have slowly gotten better but sill happen 2-3 times a day. I usually take stimulants for ADD but I am now unable to take them, or at least take at most a third of what I did with out problems previously, because of some frightening cardiovascular effects. Chest pain, anxiety, palpitations, tachycardia.
I went to another doc, who seemed unsure if she could hear a murmur, but knowing I was worried about the effects has referred me to a cardiologist. I didn't tell either the ER or the other doc about the drug use.
Now about three weeks later, the palpitations have improved but I still have very high anxiety levels, which is unusual for me, and frequent rapid heart rate. My heart rate shoots over 100 and stays there probably 3-5times a day. The palpitations have improved but still occur, especially when laying down.

I'm not sure what's going on, but it is frightening. It has gotten better incrementally so far and I can only hope it will continue to do so. I used to think I knew a lot about drugs and pharmaceuticals (while I don't rival some of the admins here, I know a pretty good bit), but this experience has really shown that the unknowns are really really dangerous. When I first heard this was in town I refused to try it, calling my friends dumb for trying it. Then I tried it, liked it, used it a few times, felt the overwhelming compulsive nature of the drug, unlike anything I have experienced, and also caused my body some harm. Wish I hadn't tried the stuff. I've tried several RCs in the past, and vie been following the scene for years, but Im done now.
One benefit I'm trying to draw out of it though is a new found health consciousness.
Enduin, how are things now, have you noted an improvement over the past month or so? I believe these acute issues may be due to an impurity, as the last 3 times I used it were different in character, (less euphoria, less potency, more cardio effects, severe hyperthermia on one occasion, and are the proximal cause of these toxic symptoms).

I'm interested to hear of anyone else with similar cardio toxicity.

I was quite unsure if to post this here on in "how toxic is meph" thread, decided for this hoping I chose right.

I'd basically like to share my experience, and comment on a few hypotesis that have been made over time in different threads, please bear with me.

I used meph 3 times, first time it was crystally stuff from a super reputable vendor, insufflated 100mg, best high with an incredible rush, yet not the strongest, side effects were some gurning, dry mouth, everything as expected from the kind of substance, and next day mouth nevralgia that lasted couple of days (likely I was clenching all night).
Second time it was fluffy stuff from another vendor and was after 2 months; this was the strongest high but not the best, with no rush but a building up high which culprit was a moment I suddenly got covered by sweat from head to toe and felt outrageously high. I'm sure if it wasn't for the unbeatable sense of wellbeing and euphoria I'd had freaked out. Side effects were a super gurning to the point I couldn't finish even one sentence without chewing my jaws in the middle, dry mouth like never before, breathlessness. Amounts were 100mg insufflated, 150mg bombed, 30mg insufflated. Oddly enough after the first line the bomb didn't have any effect. after I got home at early morning my BP was quite normal like 140/70 but HR was 136. I got some light gurning and dry mouth the following day as well, and fatigue and breathlessness for up to a week.
Third time was crystally stuff but from again a different vendor, and a month after the second experience. Amounts were 100mg, then other 100mg, then 30mg all insufflated and well spaced. The high was nice but the lightest, gently rising; the gurning was stronger than the first but much less than the second and so the dry mouth, so still quite in a normal range. after the second line I noticed some palpitations, like I did strongly feel my heart pounding, even if it wasn't racing. No big after effects in the following days, but this weird heart "awareness" started showing up many times, in particular while tripping on a blotter which resulted in a bad trip
So when I got home from vacations and having this thing for a week long I went to a cardiologist to get checked. He's been very accurate, measured everything, made an echography of my heart, checked chambers, valves, etc. It was all damn right. I also have to add that everytime I used to get this palpitations I checked my values and both BP and HR were perfectly normal.
Also I noticed there were some particular times where the issue was more likely to show up like after lunch and when going to bed or waking up in the morning, and that for two times it was triggered and lasted few days after using some nasal decongestant (one based on ephedrine and the other on tramazoline). I also noticed that caffeine didn't result in anything, but didn't feel like to make experiments with other stronger stimulants cause I think that understanding is a good thing but trying to recover is better.
I went under a one month cycle with body building arginine on november (last meph intake has been in august) with no real improvements, and I'm undergoing a month with another pharmaceutic arginine supplement now that resulted in a very noticeable improvement: even tho these events were very slowly getting rarer month by month, I now am palpitantion free since I started and somehow feel my heart is "healtier". I know this is not scientific stuff, but I can't explain it any better.
Now I've been reading of many hypotesis, the 4-methylephedrine vasocostrictive issues, and recently the dermatomyositis one. I think that while probably both vasocostrictive metabolites and immune issues plays a role, it's more about a receptors upregulation of some sort. I have to add that I have autoimmune disease and got blood tested two weeks after the last experience with nothing out of ordinary concerning the immune system.
This heart issue I had really felt like my heart was hyperexcitable, and was reacting to things (meals, changing of standing/laying positions, small doses of vasocostrictors in the for of nasal decongestants) that usually don't make the difference. If I had to guess I'd point on 5-ht receptors, but I have no chemistry/biology knowledge, so I'm just guessing based on what I read here and on the web. Btw my buddy used my same amounts the same times but didn't experience any heart issue or anything other than than the transitory ones, and since I notice there's a big variance of side effects between different people, I'm led to think that the receptors upregulation hypotesis can work since everyone's receptors respond differently to different substances.
There's one last thought, a little OT but still: At beginning of 2009 people were all raving about how amazing meph is, only few morons who went on week binges reported purple knees, ect. Now There's plenty of people that get problems even with single doses, or a moderate use. I can't help but thinking that like it happens with everything the increased request for meph led to a decrease in quality in order to make more available, in spite of most thinking now the meph is better cause it's cristally, and some unknown impurities could be even more responsible than meph itself for most side effects and long lasting problems. But this is just IMHO.

 

[bpaddy32]

bollox

Foot off pal. eb]verything you have posted is absolute balls.I did the shi, about a gramm every day, up to two.for six months and never had an issue with me feet. maybe its cause i wash every now and then or change me socks orcause i live i a relatively cool place, then again maybe noit. Is this site fullof crappers like , trying to puts us alloff having a good time or what. Cop on and get a fukin life or do some drugs. U wanker

 

[bpaddy32]

Calm down pal. I did at least a gramm a day from mid January till end of June, plenty o days doing two. And it was that brill pure gold brand.Cant do it now cause the law chaned here end June, (OIRELAND).I'll be 51 in a couple o months, that ,makes me a 1959 model, which i'd bet is a tad older than ur guud seld. U got a fit o young dude paranoia,probably cause ur also smokin big reefers and downing quarts o alco for fun everybweekend. Calm fukin down, ur fine.
Paddy

 

[Aldousage]

I've enjoyed mephedrone several times (maybe 7 or 8 over a year). I never exceeded 400mg each time, and always waited at least two weeks between experiences (not always easy with such a euphoric drug...).

I think the major problems with stims like this one are that young, "immortal" users take excessive amounts, use too frequently, and/or take alcohol and other drugs simultaneously.

Due to recent legal restrictions on mephedrone, I've just ordered some flephedrone. I'm hoping it will be very similar.

 

[vortex30]

Hahaha, I've just read 2 posts from the most immature 50+ I've ever met...

BUT

I oddly agree. People need to try not to focus on these side effects as they go about their day to days. You're alive and you've got your whole life ahead of you to fix these issues which have only recently shown up. This is the long-term effects thread, now it's good to hear EVERYTHING we can, and I'm not saying don't post about them, definitely not. What I'm saying is you need to start taking actions now to make amends with your body and fretting over these side effects day to day will just cause them to be more pronounced. I'm almost 4 months clean after 1.25 years of once a week or more with 4 months of binging 2-4 days a week on the stuff pretty much weekly. Am I cured, after 4 months no mephedrone, minimal stims, exercise and other health conscious actions taken? Nope, but I'm much better than I was when I stopped. 1-2 weeks of heart issues is very common with this drug it seems. Mephedrone is obviously one to avoid and I wish that I had. But he's got a point, try to chill out on the worrying day to day. Things will improve with time; it's inevitable. You probably haven't done long-term damage with a few sessions on it, so just focus on a fast recovery. I worry I've done some level of long-term damage but I'll wait for the one year mark and see how my health is then.

This stuff takes time...

EDIT

As far as progress has gone. I can smoke cigarettes without them increasing my anxiety. My heart only rarely has a shooting pain and it almost always follows an awkward movement of some sort, so this side effect may be entirely gone. But my heart still feels slightly 'numb' constantly, or, maybe it's not numb at all, it's that I can actually feel it pumping in my chest? Whatever it is, my heart doesn't feel the way it used to, haha. My heart feels good when I run, it's not in pain...My lungs on the other hand (smoker ). My knuckles are still a bit pink on index and middle fingers but my knees have returned to normal colour. I haven't had sleep paralysis once since quitting (fingers crossed). Overall I feel a lot healthier, but there's still some issues. Pins and needles in my arms and hands from time to time and this constant feeling of being just a bit on edge, like I can't fully relax (mild hypertension?). Thinking of the past 2 years and all the damage I have done really brings me down and thinking of specific, very long binges makes me feel temporarily like I did the days following them. I smelt an old bag that had 100g of Mephedrone in it at one time several months ago. My face and spine started to tingle and I had a moment of utter shock just from the smell. My nose...Still not in great shape, but getting better. I seem to have a deviated septum, curving into the right nostril. My left nostril is still fairly 'floppy' if I breathe in hard, but it's SLOWLY getting stronger, the right nostril is fine (I snorted mostly with the left, as the right would often be clogged from just a few lines). My GABAergic use has not surprisingly decreased loads thanks to quitting. No more terrible comedowns to deal with and I can sleep just fine at night.

 

[EFC18]

Hahaha, I've just read 2 posts from the most immature 50+ I've ever met...

BUT

I oddly agree. People need to try not to focus on these side effects as they go about their day to days. You're alive and you've got your whole life ahead of you to fix these issues which have only recently shown up. This is the long-term effects thread, now it's good to hear EVERYTHING we can, and I'm not saying don't post about them, definitely not. What I'm saying is you need to start taking actions now to make amends with your body and fretting over these side effects day to day will just cause them to be more pronounced. I'm almost 4 months clean after 1.25 years of once a week or more with 4 months of binging 2-4 days a week on the stuff pretty much weekly. Am I cured, after 4 months no mephedrone, minimal stims, exercise and other health conscious actions taken? Nope, but I'm much better than I was when I stopped. 1-2 weeks of heart issues is very common with this drug it seems. Mephedrone is obviously one to avoid and I wish that I had. But he's got a point, try to chill out on the worrying day to day. Things will improve with time; it's inevitable. You probably haven't done long-term damage with a few sessions on it, so just focus on a fast recovery. I worry I've done some level of long-term damage but I'll wait for the one year mark and see how my health is then.

This stuff takes time...

EDIT

As far as progress has gone. I can smoke cigarettes without them increasing my anxiety. My heart only rarely has a shooting pain and it almost always follows an awkward movement of some sort, so this side effect may be entirely gone. But my heart still feels slightly 'numb' constantly, or, maybe it's not numb at all, it's that I can actually feel it pumping in my chest? Whatever it is, my heart doesn't feel the way it used to, haha. My heart feels good when I run, it's not in pain...My lungs on the other hand (smoker ). My knuckles are still a bit pink on index and middle fingers but my knees have returned to normal colour. I haven't had sleep paralysis once since quitting (fingers crossed). Overall I feel a lot healthier, but there's still some issues. Pins and needles in my arms and hands from time to time and this constant feeling of being just a bit on edge, like I can't fully relax (mild hypertension?). Thinking of the past 2 years and all the damage I have done really brings me down and thinking of specific, very long binges makes me feel temporarily like I did the days following them. I smelt an old bag that had 100g of Mephedrone in it at one time several months ago. My face and spine started to tingle and I had a moment of utter shock just from the smell. My nose...Still not in great shape, but getting better. I seem to have a deviated septum, curving into the right nostril. My left nostril is still fairly 'floppy' if I breathe in hard, but it's SLOWLY getting stronger, the right nostril is fine (I snorted mostly with the left, as the right would often be clogged from just a few lines). My GABAergic use has not surprisingly decreased loads thanks to quitting. No more terrible comedowns to deal with and I can sleep just fine at night.

Great post, agree with all you're saying and although I'm not at the stage you are just yet (well done btw) I'm getting there and I am going through all the symptoms you're merely reflecting upon.
Quick note on the bit I bolded, so true...whenever I can smell it, often opening up the baggy with it in, my mouth will start to salivate and I'll feel very strange - I don't think it's the kind of salivation as a result of something appetising either, almost like my body is preparing it's self defense mechanisms, it's very strange.
I still enjoy that moment though.

 

[fastandbulbous]

Foot off pal. eb]verything you have posted is absolute balls.I did the shi, about a gramm every day, up to two.for six months and never had an issue with me feet. maybe its cause i wash every now and then or change me socks orcause i live i a relatively cool place, then again maybe noit. Is this site fullof crappers like , trying to puts us alloff having a good time or what. Cop on and get a fukin life or do some drugs. U wanker

Yeah the place is full of people trying to stop you having a good time 8)8).

In future, before opening your mouth and letting the diarrhoea pour out, read a bit about pharmacology - drugs effect people in different ways, some badly, some hardly at all

 

[AlkaloidsEye]

f a b That's one of the very positive highlights i'm really enjoying about bluelight. The fact that everyone can come up here and post what's going on with them. It's useful to have some basic generalizations about how drugs work, but getting this field data back is much more real.

As for mephedrone smell? I have a feeling that if you use it more than once or twice you will recognize the smell always. At least it's that way for me. I can smell it on people's money sometimes. lol

 

[vortex30]

Great post, agree with all you're saying and although I'm not at the stage you are just yet (well done btw) I'm getting there and I am going through all the symptoms you're merely reflecting upon.
Quick note on the bit I bolded, so true...whenever I can smell it, often opening up the baggy with it in, my mouth will start to salivate and I'll feel very strange - I don't think it's the kind of salivation as a result of something appetising either, almost like my body is preparing it's self defense mechanisms, it's very strange.
I still enjoy that moment though.

Thanks man! That is EXACTLY it, my mouth salivated too, but it's like my body is preparing to purge something awful out of it or setting up it's defenses or something as you said. I oddly enjoyed it too, lol, but that's my self-destructive side coming out, wanting me to do more and I now know consciously that the stuff is just filthy and I don't want any part of it anymore. Was a freaky moment though, smelling mephedrone after 3 months clean, not seeing it or smelling it once in that time and immediately getting hit by this weird sort of rush. I don't think this particular side-effect will ever go away, it's too strongly ingrained in my mind/memory now I feel.

 

[ColtDan]

been doing it for around a year now. 500mg every weekend, or every other weekend. i think severity of side effects seem to depend on the quality of the meph. 4 months into its use i decided to do it 2 days in a row... bad idea... it gave me one motherfucker of a comedown which lasted for days, huge lack of motivation, heart palps, depression, etc. ever since then i get bad come downs, heart palps, all the bad effects basically. pins and needles, numbness, red knuckles, hot/cold hands... you name it.
recently though, the side effects seem to have gotten less worse... no idea why. i never increase my useage, which is good as some people binge on this stuff like something crazy. and i only take meph after a few pints. promised myself i would give this stuff up months ago... but its too damn good. especially at music events. had some of the best times of my life on meph. never been on a massive binge, 500mg over 8/10 hours isnt so bad i suppose. i eat healthily, get loads of exercise, and try and be as healthy as possible during the week. the heart palps can be very worrying sometimes... never had any pain as such though, just a strange heavy heartbeat and it feels like my heart flutters. also get paranoid on the come downs, and question myself, who i am etc. then i wonder if my judgement is correct about the paranoid feelings... or if its the come down which is making me think like it. pretty shit. guess i have a love/hate relationship with this stuff

 

[EFC18]

Colt I have been feeling the paranoia at times too. Unlike most people who say that was never an aspect of their personality though, I do often worry alot about the kind of perception I've given off to people, and it's not hard for me to think I've given a bad impression, made a fool of myself, or I'm boring someone when talking to them and shit, like a search for validation. Mcat definitely magnifies that definitely, I remember getting the bus back to my house yesterday and I did look rather scruffy as you do after a night on it, but I was convinced everyone was looking at me and talking about me, I just convinced myself to ignore it and it passed.
Every time I have taken it too far I've always felt so guilty in the aftermath, but I've always managed to convince myself "Oh you exaggerated, you werent that bad, you haven't fucked yourself up, just live a little" so I've only had a couple of hours sleep since tuesday, like a 4-something day binge, when you get to a stage where that is acceptable...

Thanks man! That is EXACTLY it, my mouth salivated too, but it's like my body is preparing to purge something awful out of it or setting up it's defenses or something as you said. I oddly enjoyed it too, lol, but that's my self-destructive side coming out, wanting me to do more and I now know consciously that the stuff is just filthy and I don't want any part of it anymore. Was a freaky moment though, smelling mephedrone after 3 months clean, not seeing it or smelling it once in that time and immediately getting hit by this weird sort of rush. I don't think this particular side-effect will ever go away, it's too strongly ingrained in my mind/memory now I feel.

Haha rather similar to me then, you never want to be the first one to suggest calling it a night, I always want to just keep going. I've got quite a few sensible mates but I went out recently with my more laid back mates and we were so bad, just kept on encouraging and enabling each other. "Yeah might as well have another line", "just finish this gram" sort of like massaging each other's guilt.
I mean right now, since Tuesday, I have only had bout 7 hours sleep. That was on Thursday I slept in the daytime, 10am - 7pm then went out again that night. I mean I started Uni in two weeks thats why I've got this free time now, and I have just taken it to ridiculous levels. You are right you've really got to keep jabbing the self-destruct button to get to these levels with mephedrone, the progession has been very steady from "a line a night, only with x mate", "couple of lines", "half a gram", "only once a week", "only when I'm out in town", "only when I'm with my mates", "only when I'm drinking" and then just now, really just fucking myself up for no reason. Anyway this has taken a long time, I started using round new year. Health effects that I've noticed is high blood pressure, which manifested itself in these black dots flying through my vision like the day after a session, happened once or twice recently, I think it is called hypertensive retinopathy. I haven't had this checked my a Doctor for obvious reasons! I don't get the blue knees or hands or anything like most have mentioned and I never have done. I've never felt like I'm going to collapse, but my main health concern I've put at the bottom of this post.

f a b That's one of the very positive highlights i'm really enjoying about bluelight. The fact that everyone can come up here and post what's going on with them. It's useful to have some basic generalizations about how drugs work, but getting this field data back is much more real.

As for mephedrone smell? I have a feeling that if you use it more than once or twice you will recognize the smell always. At least it's that way for me. I can smell it on people's money sometimes. lol

Yeah. It is very recognisable once you've been around it long enough - but yes I do agree with you too, the feedback and sharing of tales can be rather therapeutic. Obviously got to take the anecdotal evidence with a bit of salt but you can still learn things from it and occasionally there are some budding chemists with surprisingly advanced pharmacological knowledge who actually understand the substances we kind of ingest without much thought.




Erectile Dysfunction
Needed to bold this bit to bring the focus to my biggest concern (and thought it would make for a nice ironic bit of humour ) at the moment. Obviously shrivelled dick when on it everyone is aware of, but now day or two after its really hard to get motivated and also, physically, it just doesn't seem to go beyond a semi. this is really fucking worrying me as there is a girl I have been making moves on, and getting very good responses, it would be a hell of a way to spoil it for myself as she doesn't even do drugs either.
But yes this seems to be a problem for me, hard to judge whether it is long term or permenant because I have literally been binging these last two weeks.
I expect nothing but condemnation obviously, I'm more aware than anybody that my antics have been self-destructive, I'm hoping for some leniency amongst my fellow fiends in this thread...
thanks anyway guys

 

[LukeAngelo]

I took Mephedrone for about 9 months, basically every weekend. Dosing from about 2 to 11 grams in a weekend. I was experiencing a lot of nasty side effects. Anxiety, depression, memory loss, problems with speech etc., So I decided to stop. After a month of not using meph I came up with a skin rash which has covered my whole body. I have a constant throbbing sensation in my legs. 4 months on with out taking it, I'm still experiencing these sensations, getting better over time though. I had 4 high blood pressure readings from the doctor and I had around 12 blood tests to find the cause, including the throbbing legs. They checked my Liver, Kidneys, etc. Every result came back normal. They said the blood pressure readings may be due to Meph. I've had a cough for about 4 months as well, gradually getting better overtime. One of the worst side effects is now being a hypochondriac. I had a skin rash and was certain it was HIV. Was tested and came back negative. Never had any of these side effects from Ecstasy with regular use. Worst drug I've ever taken.