True. Politicians have a lot to answer for. A lot of this shit is caused by prohibition in the first place. Our own version of the Torys the ironicly named Liberal party is trying to take the knife to our much loved health system. They want an American style health system where everyone pays. That would be a disaster. Still i think the companies selling rc benzos are pretty bloody low. They are just making a killing out of creating addicts to untested chemicals that your health system will be left with the aftermath to deal with. Indefensible in my book as a nurse.
Not all of the drugs are completely untested, obviously Etizolam is pharmaceutical drug used in alot of countries, and the first 'true' NPS benzodiazepines - 2, Chloro - Diazepam (Diclazepam), Flubromazepam and Pyrazolam are drugs developed and researched by Roche in the 70's when theywere releasing benzodiazpine based medicines every 5 minutes. Just because the above mentioned drugs were not developed into medicines, this does mean that they were not extensively researched including human trials. This means that these drugs still have the basic safety profile of any benzodiazepine, and there are more obvious reasons why they were not brought to market, there is quite alot of literature on the web about these drugs and not once has their safety profile been questioned. Diclazepam (2,Chloro - Diazepam) was more or less redundant due to it similarity with diazepam, Roche's flagship benzodiazepine. They both share very similar effect profiles, but Diazepam is faster acting (as quick as 15 minutes orally) so there was no commercial benefit in bringing out a slightly inferior but otherwise identical product to Valium. Flubromazpeam was explored as a hypnotic due to its sedating qualities, but medium duration quick acting benzodiazepines make for the best sleeping pills, and the long latency between the administration of the drug and its taking effect, along with its ridiculous duration of action, meant it was never going to make for commercially viable hypnotic. Again though, its still been through Roches research machine and there is nothing to suggest that flubromazepam is particularly unsafe either.
Where its starts to get messy is when it comes to the second generation of NPS benzos, the triazolo franken drugs that the NPS manufacturers have taken it upon themselves tp cook up, most specifically flubromazolam (the 'triazolo' version of flubromazpam) and Clonazloam (Clonitrazolam), the triazolo version of Clonazepam (Klonopin/ Rivotril). There are other untested brand new NPS benzos such as Nifoxipam, but as it is already a well understood active metabolite of Flunitrazepam, a pharmaceutical that is widely used, I wouldn't worry about its safety as much.
Just like prescription benzodiazepines, at least some of these drugs could be taken safely. You are right Consumer, but in my opinion the law is as much to blame as it does not allow companies selling these drugs to provide information on their safest use. Yes, you can argue that the RC vendors are irresponsible selling these drugs, but they sell other items as well as benzodiazpines. When it comes to the other products they sell we have even less of a clue what they may be poisoning us with. At least we have a basic understanding of how benzodiazpines work in generalo, which is more than can be said for n-bombes, 3fpms, MDAI and the like.
Its not a great situation but if the shit does hit the fan first aid wise there is no suggestion flumenzil will not treat overdoses involving NPS benzodiazpeines. I cant think of an established treatment for any other NPS on sale.
Please dont think im defending the sale of benzodiazpines like this, Im just trying to point out that their supply is no worse than any other drug that carries risks along with its useage.
Which is all of them as far as I can remember