Oh aye, without doubt. :D
There was a short period around 2007 / 2008 where supermarkets and even the odd offy experimented, but it either wasn't profitable or they became havens for pimps, whores, crackheads and people like me, and thus a police problem. So the council clamped down on it.
A few pubs and clubs have attempted similar, but with Manchester's gang scene being the way it is, the only establishment that was ever able to do 24-hour opening properly, let alone 24-hour licensing, was Jilly's, and that's because it was protected by a biker gang whom not even the Gooch in their prime would consider fucking with. If you'd ever seen 'em, you'd know why.
The Gay Village is possibly the only viable after-hours option.