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Psychedelic Drugs
Advanced discussion of psychedelics and dissociatives
Psychedelic Medicine
A knowledge base for those interested in the medical treatment potential of psychedelics.
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CHRONIC PAIN | +80 articles
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☮ Social ☮
PD Social Tripping Thread: aLL aBoArD tHe MoThErShiP 👽🛸
Kaleida
Nov 15, 2022
113
114
115
Replies
2K
Views
116K
Aug 11, 2026
iom
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Sticky
☠ WARNING ☠
*WARNING* Chronic ketamine/dissociative use causes bladder/organ damage
Deleted member 290563
May 19, 2019
24
25
26
Replies
514
Views
90K
Aug 7, 2026
blig-blug
Sticky
Miscellaneous
Official Hall Of Shame Thread - Less Fiction More Facts
red22
Mar 14, 2026
2
3
Replies
48
Views
3K
Aug 5, 2026
red22
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🌟🌟 Social 🌟🌟
PD Social Thread 2022-2026 v. Year of the Phenethylamine
arrall
May 25, 2022
196
197
198
Replies
4K
Views
237K
Aug 4, 2026
doubledog
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S
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Health
Making Ayahausca
scabbard
Apr 7, 2026
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4
Replies
65
Views
4K
Jul 19, 2026
mr peabody
Sticky
Health
Psychedelic Safety: Guidance on difficult experiences & dangerous combinations
Xorkoth
Mar 29, 2016
5
6
7
Replies
120
Views
65K
Jul 13, 2026
mr peabody
Y
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☠ WARNING ☠
Be careful with Nitrous Oxide - nerve damage, paralysis, anemia, high homocysteine.
yaesutom
Aug 18, 2024
2
3
Replies
43
Views
6K
Jun 22, 2026
mr peabody
Sticky
☠ WARNING ☠
[Important NBOMe warning] Taking unknown blotters sold as LSD
Solipsis
May 30, 2014
11
12
13
Replies
255
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187K
Jan 8, 2026
xdrc
Locked
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Forum Guidelines
PD Rules & Forum Guidelines
solistus
Oct 5, 2010
Replies
1
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69K
Jan 16, 2022
Xorkoth
Dissociatives
"Ice / Rock" Ketamine VS "Pixie Dust" / "Glass" & Loose Powder.
Zopiclone bandit
Saturday at 12:13 PM
Replies
15
Views
195
20 minutes ago
KetWise
K
R
Phenethylamines
2,4-dimethoxyamphetamine - some short info
ralf2
Friday at 9:42 PM
Replies
12
Views
267
Today at 11:15 AM
Allylbenzene
S
Miscellaneous
Trip stoppers. Are they bullshit?
soulless_curiousity
Jan 30, 2026
2
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37
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2K
Today at 7:38 AM
koolman69420
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The Big & Dandy Syrian Rue & Harmala MAOI Alkaloids Thread
Crazy Cloud
Sep 18, 2002
9
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11
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203
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53K
Yesterday at 11:52 PM
red22
O
Tryptamines
L. asiatica - lilliputian hallucinations
Opana313
Jan 22, 2026
3
4
5
Replies
81
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6K
Yesterday at 10:59 AM
Allylbenzene
☛ Official ☚
The Big & Dandy DOC Thread - Third opinion
Solipsis
Jan 16, 2014
76
77
78
Replies
2K
Views
248K
Sunday at 10:30 PM
Allylbenzene
Lysergamides
The LSD Megathread - 5th version 2026
red22
Jan 13, 2026
2
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20
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2K
Sunday at 5:32 PM
red22
Lysergamides
Novel LSD analogs. Weary.
FractalPerogys
Aug 10, 2026
Replies
1
Views
196
Sunday at 7:35 AM
Viraldrome
Esoteric
Psychedelics don’t distort reality - they reveal how your brain constructs it (video)
(~);}
Aug 11, 2026
Replies
12
Views
208
Saturday at 9:20 PM
foodcrisis
C
Phenethylamines
How dangerous is 2C-B for a tired nervous system?
currentsanna
Saturday at 8:59 AM
Replies
8
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122
Saturday at 7:44 PM
Freeotrope
Phenethylamines
0 danger with mescaline and the heart?
donotdothis
Jul 20, 2026
Replies
5
Views
317
Saturday at 5:53 PM
donotdothis
Tryptamines
The most fucked up Research chemical story I have ever had the (dis)pleasure to occur
Axemancometh
Aug 8, 2026
Replies
13
Views
441
Saturday at 9:05 AM
iom
I
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Miscellaneous
The Big & Dandy Microdosing Psychedelics Thread
Casual.dream
Nov 4, 2015
2
3
4
Replies
67
Views
19K
Saturday at 5:27 AM
red22
maois (in ayawaska/ayahuasca) and suboxone- safe?
daysonatrain
Jun 24, 2009
2
Replies
27
Views
10K
Saturday at 3:09 AM
red22
D
Health
New molecular structure for psychedelic drugs : ZC-B and LPH-5
Dr.Methyl
Feb 1, 2025
2
3
Replies
40
Views
3K
Saturday at 1:26 AM
Allylbenzene
Help!
Question about Mescaline + Medication interactions.
Didgital
Friday at 6:36 AM
Replies
3
Views
109
Friday at 10:22 PM
realgar
Tryptamines
DMT collutory?
donotdothis
Friday at 7:45 PM
Replies
1
Views
60
Friday at 8:30 PM
donotdothis
☛ Official ☚
The Big & Dandy HBWR/MGS/LSA Thread - Part 3: Fluffy Dreams Continued
Solipsis
Nov 14, 2012
13
14
15
Replies
296
Views
38K
Friday at 6:27 PM
Esperighanto
☛ Official ☚
The Big & Dandy 5-MeO-DMT Thread - Second Launch
Jesusgreen
Nov 23, 2011
21
22
23
Replies
458
Views
92K
Friday at 5:37 PM
Esperighanto
Phenethylamines
The Big and Dandy 25x-NBOH Megathread | Post your 25x-NBOH info and questions here.
simstim
Apr 7, 2022
5
6
7
Replies
128
Views
14K
Friday at 5:33 PM
Esperighanto
N
Lysergamides
Curiosity about how make my own lsd or similar drug
newalex
Friday at 12:09 PM
Replies
1
Views
84
Friday at 12:21 PM
Allylbenzene
P
Nootropics
DET/DMT synergy suggest a distinct "Psychedelic Modulator" subclass—structural & observational notes
pantsoph
Aug 10, 2026
2
3
Replies
40
Views
660
Friday at 6:42 AM
Freeotrope
Phenethylamines
Vaping/smoking mescaline
red22
Feb 18, 2025
2
Replies
34
Views
2K
Thursday at 4:59 PM
Allylbenzene
Health
Question about mushrooms and intense abdominal pain
M!$TER-ED
Aug 6, 2026
Replies
8
Views
203
Thursday at 1:32 PM
M!$TER-ED
R
Lysergamides
Microdosing LSD while on drug pressure meds?
redman91
Wednesday at 9:57 PM
Replies
8
Views
175
Thursday at 9:04 AM
iom
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