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What is wrong with the MDMA available today?

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So basically we just need 3,4-DMA and TMA to mix in with the mdma of today and we should be good to go right? Either that or get a seizure like that one lad.
 
My connect charges <<cut price>> for a gram of MDMA, but it is verifiably made from sassafras bark.

Contrast that with about <<cut price>> on the darkweb.....clearly there is a big difference there.

I have yet to try this stuff, haven't had the right occasion. but I'm curious if it will be like the good old stuff.
 
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cryptix420 said:
My connect charges <<cut price>> for a gram of MDMA, but it is verifiably made from sassafras bark.

Contrast that with about <<cut price>> on the darkweb.....clearly there is a big difference there.

I have yet to try this stuff, haven't had the right occasion. but I'm curious if it will be like the good old stuff.
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<<cut price>> is a big leap of faith without even trying haha
 
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Jmoda said:
I know people will say this is placebo and what not, but i get this 100%. Different batches of mdma can have their own signature feel. I totally have gotten the "creamy" roll before (wasnt a pressed pill that said this or anything), from independent observation in the moment!
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G_Chem said:
I too 100% agree and feel it clouds the overall discussion as well. It’s hard to pinpoint what’s meh and magic when each batch has its own unique feel.

Over the years I’ve been able to nail down some of differences (which I talked about in another thread) batch to batch which I attribute to small variations in isomers, impurities, and polymorphs.

-GC
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I agree with this as well guys, from 1996. Certain presses just had rheir own special magic signature and quality. No way could I accept it being just dosage related, and the whole set/setting supposition is abused IMO, whipped out any time as a simple explanation.
 
cryptix420 said:
My connect charges <<cut price>> for a gram of MDMA, but it is verifiably made from sassafras bark.

Contrast that with about <<cut price>> on the darkweb.....clearly there is a big difference there.

I have yet to try this stuff, haven't had the right occasion. but I'm curious if it will be like the good old stuff.
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We do not allow price discussion anywhere on the MED forum, please keep that in mind. I'm on my cellphone now but I'll edit out the price later today, or you can do it yourself
 
BlueBull said:
We do not allow price discussion anywhere on the MED forum, please keep that in mind. I'm on my cellphone now but I'll edit out the price later today, or you can do it yourself
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I think it's actually a BL wide rule, for everyone's reference :P
 
I'm on what feels to be approximately 30 to 35 milligrams MDMA.HCl ('Ecstasy' pills or rolls) from a Red Bull pressed pill. Feels pretty good!

 
Got back the results for my recent sample (not consumed yet).

www.drugsdata.org

DrugsData.org (was EcstasyData): Test Details : Result #9535 - MDMA, 9535

DrugsData (EcstasyData) lab testing result
www.drugsdata.org www.drugsdata.org

Pleased to see that I have submitted a sample that comes back as just MDMA. Not MDMA + MDA, or MDMA + some weird byproduct. Of course, I don't know what the percentage of purity is, but at least there are not some weird remnants of the synth process that are showing up in the sample. Guessing the Simon's reaction must just be due to my Simon's test getting old.

Also, this submission has made me realize something potentially significant.

They say that I sent 20 mg, but I weighed this before I sent it and my scale said it was about 60 mg.

Could my issue be that I have a bad scale? Seriously. If my scale is weighing out mg significantly "off," then that would explain A LOT. Have we even discussed this here?
 
indigoaura said:
Could my issue be that I have a bad scale? Seriously. If my scale is weighing out mg significantly "off," then that would explain A LOT. Have we even discussed this here?
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I doubt it tbh. It's been stated many times that even upping the dose significantly doesn't turn meh into magic, it just creates a stronger meh experience.
 
You can get an ok set of calibration weights for $15 on Amazon, so this is probably the easiest theory yet to test.
 
Nvm I found it, when the n-formyl intermediate is found it’s usually in 15-20% amounts.

@indigoaura one thing I notice about the reagent results is how brown the Marquis looks, to me that puddle looks different than what I usually see. But maybe it’s down to some variable like older reagent or something..

-GC
 
G_Chem said:
Nvm I found it, when the n-formyl intermediate is found it’s usually in 15-20% amounts.

@indigoaura one thing I notice about the reagent results is how brown the Marquis looks, to me that puddle looks different than what I usually see. But maybe it’s down to some variable like older reagent or something..

-GC
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Yeah, I really wonder about the variation in reagent results.

Just look at the difference in all my samples, for example:

Known Meh - https://www.drugsdata.org/view.php?id=8547
Known Meh - https://www.drugsdata.org/view.php?id=8546
Known Meh (but a bit better than most) - https://www.drugsdata.org/view.php?id=6072 (this was a sample I only had very little of. Never got to experiment with higher doses)
Unknown (new) - https://www.drugsdata.org/view.php?id=9535 (You can see the weird circling effect on the top marquis and mecke results)

@G_Chem's known magic - https://www.drugsdata.org/view.php?id=8890

I have long wondered about the distinction in the written Mandelin results. Why Purple-Blue-Black for some and Purple-Brown for others? Is this just a matter of individual difference in how the lab techs note the results? My meh samples were both recorded as purple-brown, your sample was purple-blue-black, and my new sample was blue-purple. Yet, this does not line up with what I SEE in the results as they are pictured.
 
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G_Chem said:
While ya’ll start compiling I’ll add yet another example showing how MDMA can vary...

As we know safrole, particularly American sassafras oil, was most prevalently used in the 90’s and early 00’s. Even when safrole was still being used there was a switch over to international sources of safrole which had a different constituents.

Here’s a ref which says they analyzed sassafras oil (presumably American sassafras) and found camphor, eugenol, dimethoxyalyllbenzene (methyl eugenol) and trimethoxyalyllbenzene (elemicin).

Gas Chromatographic and Mass Spectrometric Analysis of Samples from a Clandestine Laboratory Involved in the Synthesis of Ecstacy from Sassafras Oil
F.T. Noggle, Jr., C. Randall Clark and Jack DeRuiter
Journal of Chromatographic Science, Vol. 29, 168-173 (1991)

What does this mean? Well by the sounds of many old school 90’s pills still reaking of sass it’s likely that they may have had at least residual amounts of these other compounds (even with a distillation it’s possible some made it through) which would then proceed the same as MDMA to create 3,4-DMA and 3,4,5-TMA.

Both of these compounds are known to be psychoactive and I’d bet even a couple of mg of TMA would alter the experience.

Here’s also a case report as well as a side study on said case report where 3,4-DMA was found in an ecstasy sample with MDMA. While it’s obvious by the blood levels that the 3,4-Dma was added intentionally, it’s interesting to note that it inhibited an enzyme needed to excrete MDMA which for this young lady went bad. They suspect it was added to help potentiates the MDMA.

While I believe the dosage was probably equal to the dosage of MDMA in the pill, I wonder what a couple mg would do with a standard dose of MDMA?

A Case of 3,4-Dimethoxyamphetamine (3,4-DMA) and 3,4 Methylendioxymethamphetamine (MDMA) Toxicity with Possible Metabolic Interaction – OPEN Foundation

www.stichtingopen.nl www.stichtingopen.nl



So to recap, old school safrole MDMA made via Leuckart had at least 6 or so different active impurities all of which would likely alter the experience in some way different from today’s product. Was it better? Maybe. Is good MDMA still around? You bet your ass it is!

Those active impurities one more time.. MDA, TMA, 3,4-DMA, n-formyl-MDMA, MDDMA, and the two compounds in that one study too long to say again lol.

The 3,4-DMA interests me in particular as it seems like it could be culprit for why MDMA used to last so much longer... The batches which I’ve found to have that all night lingering effect also were safrole smelling.

-GC
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This is all very interesting. I had commented earlier in the thread about how different types of sassafras trees have different combinations and amounts of active ingredients. I wondered if this could impact the outcome, but the comment was dismissed at the time.

However, it seem relevant to me, because the origin of safrole has changed since the 90s/00s as well. The East Asian trees are significantly different than the North American trees. There is even variation in the tree leaves depending on the season they are harvested (https://journals.sagepub.com/doi/pdf/10.1177/1934578X0800300529). There also may be variation in composition depending on the color of the stem (if Native American traditions are believed) (https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/sassafras).
 
Another relevant article related to variations in safrole:


Safrole, the main compound in the essential oil of several plants of the Laurel family (Lauraceae), and its secondary product piperonylmethylketone are the predominantly used precursors for the illicit synthesis of 3,4-methylenedioxymethamphetamine (MDMA) which is, in turn, the most common active ingredient in Ecstasy tablets. Analytical methods with adequate capacity to identify links and origin of precursors, such as safrole, provide valuable information for drug-related police intelligence. Authentic sassafras oil samples from police seizures were subjected to comparative analysis based on their chemical profiles obtained by comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC GC–TOFMS). The enhanced separation power and increased sensitivity of GC GC allowed for the detection of minor compounds present in the essential oils which were of particular interest in case of very pure samples whose impurity profiles were not very pronounced. Discrimination of such samples was still possible even in the absence of characteristic main compounds.
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