I'm 50/50, I love being on uppers when I attend a rave, going around chatting with people, dancing, and just getting things done, being on amphetamines, ecstasy serves that purpose. When the uppers ware off, then I'll need to come down, then there's where I can do downers. If I were on ecstasy time to pull out the ketamine, if amphetamines then first pull out some opiates, then the benzos+alcohol, and its time to pass out. These days I skip the opiates as they seem rather addictve, but so are uppers. Certain days when I'm just at home I do downers.
I make sure the amount of uppers and downers I do are equal out, therefore I can ensure I get proper sleep, and enough time awake/asleep.
-PLUR