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Opioids Tianeptine Megathread v1

Let me ask this question in a better way. Does anyone know how to process api raw material tianeptine?
 
^Does not need to be “processed” in the same way benzos need to be through volumetric dosing. That being said you absolutely need a .001 scale to take this substance. 100mgs is a good sized dose for someone with a tolerance. I believe 25mg 3 times a day is the actual recommended dosage for use as an antidepressant. Please invest in a milligram scale before using again as this stuff could kill you just like any other opioid. You can get set of Gemini scales from Amazon for $20 that would be suitable.
 
If you're on this you should taper/ get off now. Because of FDA / DEA pressure is mounting on vendors. Most reputable ones are either closing or removing the sodium versions. I'm just glad I tapered myself down to about 100mg a day from 4g a day b4 this happened. Just a heads up....taper
 
Yes it seems like the beginning of the end for tianeptine. The agencies have their eyes on this so it's pretty much as good as gone.

Shame since if used in one 160mg dose on sat night and sat night only you get a great 3 hour buzz that is completely unique feeling. At 30 min mark you get warm euphoria with a slight stimmy uplift and life becomes more comfortable and exciting. It enhances good buds and small doses of hydrocodone. If you use this daily even just for a week or two it sucks you in and takes hold quickly. I will miss my Saturday ally but on to the next one I guess.
 
Has anyone iv'ed tianeptine??
I know it's dangerous! I've shoot everything in my 10 yr. Iv train!!
But is this possible???
 
Rick1488hzx said:
Has anyone iv'ed tianeptine??
I know it's dangerous! I've shoot everything in my 10 yr. Iv train!!
But is this possible???
Click to expand...

Possible? Yes, but I'd have a read through some of the threads that surround others who've tried it.

Rustygsxr said:
So far, I've been injecting into the femoral veins for about 3 weeks and they are holding up fine. My guess is that the swelling induced by chemical irritation is too much for smaller veins to handle.
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Rustygsxr said:
Just want to say some things. Don't IV tianeptine. Please. I quit about 3 months ago. I'm still trying to get rid of blood clots in my left arm from this stuff. Injecting tianeptine is not worth it!

I wish I'd have listened to people here and stopped sooner. In the interest of harm reduction, do not IV this stuff! I won't be doing it any more via any ROA. When I quit, it took me probably two weeks to be able to sit still and get comfortable. The withdrawals were just like methadone.
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736517-Injecting-Tianeptine-Pharmaceutical-Powder

-Near-FATAL-overdose-with-Tianeptine
 
Totally forgot I started this Big n Dand I'm actually contributing!!

"After one slightly missed shot I got cellulitis and ended with two staph inflections. One of which is pretty resistant to oral antibiotics meaning essentially a month of staying in the hospital so I could get IV antibiotics. I'm still taking the antibiotics now and there isn't a guarantee that although the bacteria is dead in my blood, it is hiding or could mutate."
Not to mention people on Russia losing their limbs from shooting Stablon.

Only thing I'm going to miss about the stuff is using it to replace the pain pills that the dentist can no longer prescribe in my state.
 
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I implore you with the utmost urgency to get that checked out. It might need antibiotics and lancing or thrombolytic, anticoagulant & anti-platelet therapy to prevent a thrombosis. Just please let them figure it out. I'm not comfortable advising heat or wasting any time specifically because it's Stablon/ Coaxil. Here's why:

For the first time I found out about Coaxil users from people in infectious diseases hospital on Sokolina Gora(one of the districts in Moscow).The told me about epidemic among young Moscow citizens, who dissolve Stablon/Coaxil pills in water and then inject them. Tiny crumbs block blood vessels and as a result you get gangrene. They spoke about dozens of guys and girls with no arms or legs, locked up on one of the floors of the hospital.

So then I asked my friend who works as a surgeon in the hospital N15. The hospital specialises in vein diseases. Ivan(my friend’s name is Ivan) told me that 2-3 Coaxil users a shift have been brought to his hospital every day for the past three years! And surgeons are amputating arms and legs of young people aged 17-25. “ We feel sorry not so much for them, but for their mothers, who are howling with pain:”Save my child’s legs!” We have at least 5 coaxil patients at a time in our department.

Why does gangrene start? What happens?
-If you watch the process of making coaxil substance by drug users you will see quite clearly why. They crush the pills and dissolve them in water, very often it is tap water. Then they get a disperse substance and it’s particles cause damage to a vessel and build a thrombus (clot) inside it. The thrombus starts growing rapidly. The thrombus itself is a very good environment for various microorganisms and that provokes purulent complications.
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Coaxil madness in Russia
 
So is the consensus that Tianeptine is really not good for depression because of how horrible the WD is?

I hear that it can be used as an antidepressant and some people respond well to it, but I also keep hearing people talk about how horrible the WD is, and you are talking to someone who has disliked Kratom WD and had trouble not using too much of it, and I once heard someone in here, probably somewhere in this thread, say that if you've had problems with Kratom to NEVER touch Tianeptine.

Is this stuff really best to stay away from and not consider for usage for depression if you are the type of person to often abuse substances?
 
For the benefit of anyone else who might be reading this thread and would be quite understandably scared away... The withdrawal is not an issue if you take it in sensible doses. Some of the dosing described in this thread is absolutely insane. Admittedly the prescribed dose is a little low for many, but just a little bit higher Tianeptine can be a highly effective antidepressant and even nootropic - at least in the short term, longer term benefits are harder to quantify.

It is most definitely no more or less dangerous than any other abusable substance, if abused. I don't usually like using the word "abuse" in the context of substances, but if ever it would apply, it would be to the patterns of usage in this thread. There is nothing really that special about high dose tianeptine compared to any other drug, it's not the most euphoric, interesting, if you're looking for recreation there are many better options.

Of course everyone has their preference and for some people maybe there is something special, fair enough, I wouldn't dispute this, but my point is that the reason tianeptine is abused really has little to do with any of it's inherent qualities (except perhaps the fairly short duration, admittedly), but a lot more to do with the fact that it is cheap and easily available. Of course there's nothing unusual about this either, this is the case with almost every substance demonised and stigmatised in the public eye because of widespread problem usage. It does however result in serious negative bias as far as the actual dangers of these substances in an objective sense.
 
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Mycophile said:
So is the consensus that Tianeptine is really not good for depression because of how horrible the WD is?

I hear that it can be used as an antidepressant and some people respond well to it, but I also keep hearing people talk about how horrible the WD is, and you are talking to someone who has disliked Kratom WD and had trouble not using too much of it, and I once heard someone in here, probably somewhere in this thread, say that if you've had problems with Kratom to NEVER touch Tianeptine.

Is this stuff really best to stay away from and not consider for usage for depression if you are the type of person to often abuse substances?
Click to expand...

Tianeptine is pretty great for depression if used strictly therapeutically but if someone has history of often abusing substances then it is probably a bad idea to try Tianeptine. And if that person has previous history abusing opioids then it is probably most especially a bad idea, like playing with matches in the middle of a fireworks warehouse while soaking wet from gasoline kind of bad idea.

Kratom withdrawal sucks for me, and I like kratom so I too wanna take it more than I should.... but Tianeptine? Got out of hand very quickly for me and the withdrawals are 100x worse. Kratom is benign in comparison.
 
There are several reports on the net indicating that when injected tianeptine actually causes severe necrosis, a bit like krokodil. Personally, I found tianeptine extremely underwhelming. Granted, I didn't shoot it but I have a feeling that its not worth it either.
 
Why is this thread formated so weirdly on my screen with the boxes on seperate sides of the screen instead of posts straight down? It looks much better the latter way.

Is it that way for anyone else?

Anyways, seems that NOT EVERYONE agrees that using all forms of Tianeptine in all cases is this horrible thing, and that in particular the Sulfate version rather than the sodium CAN be used for depression and anxiety with good effects and without horrible WD effects IF it is used responsibly and strictly, and some people even say it can be done with the sodium version, but I'd be much more wary there.

I still don't think I'd feel comfortable about it, but has anyone here used Tianeptine SULFATE to treat depression and/or anxiety and mood issues effectively WITHOUT it causing serious withdrawal or can they speak to the ability of some people being able to do so and how they would go about doing it?
 
Sure, If you stick to strictly therapeutic level dosing/frequency, then you won't experience those horrible withdrawals everyone talks about. I don't know what is therapeutic recommended dosage wise for the sulfate but for sodium it's 12.5mg three times a day. Sulfate is probably a little higher of a dose with less frequency, something like 25mg twice a day, but I'm only guessing here so do some research.

Can somebody use it responsibly? Of course, I think with the correct mindset going in it's totally possible for a lot of people. Probably not a good idea for addicts especially those with previous opioid issues.

I purchased Tianeptine the first time with good intentions. I enjoyed my first few therapeutic doses but unfortunately my internal addict's interest was piqued. So I tried a large dose 'just once' to see and I liked it - a lot. Soon I was taking large doses a few times a week, then daily, then every few hours. Rest is history.

I'm an addict and I give in to my urges to easily, especially with opioids. I should have known better, actually I did know better, I think in the back of my mind I I knew what would happen. So for me, it was a bad idea to get Tianeptine in the first place. For you? I don't know, you are going to have to make that decision for yourself.

Keep in mind you worked your kratom doses up very very high and eventually were using often enough to get some withdrawals when stopping. You can't do this with Tianeptine, it won't end well. The withdrawals are horrible - like heroin intensity horrible.

If you are going to use it then set strict rules: stick to strictly therapeutic doses with zero exceptions. If you break rules, then flush everything, walk away and don't look back.

Only you can make the determination whether or not this is feasible for you. It wasn't for me...
 
So I just tried converting tianeptine free acid to tianeptine sodium and am not sure if I have done it properly. This is how (maybe someone can weigh in):

Used 250mg of tianeptine free acid, 55ishmg of sodium bicarbonate (baking soda) and 80ml of water. Got the water to boiling then mixed everything in and pulse boiled at 5-10 second intervals in the microwave but it didnt react in a way that was visible like I've heard it would do. Just drank a bit of a third of the water. Eyes are heavy a few minutes after but not much else to speak of. Should it of reacted?
 
Anyone have much experience with Tianeptine Ethyl Ester Sulphate?

Been trying some of this recently, and subjectively it seems to be more mild than sulphate (Hemisulphate Monohydrate I believe is the typical sulphate version?). I've never tried sodium so can't compare to this. I've been dosing around 40mg at a time which would be on the upper end of my usual sulphate dose back when I did take this occasionally although I haven't taken any for a long time now, maybe up to a year, so I wouldn't think tolerance would be an issue. However reports on reddit and the like seem to suggest the typical dose should be a little lower... which is strange to me.

Would be very interested if anyone knows how to calculate the actual tianeptine content of this compound compared to the sulphate and sodium versions, and especially if anyone knows anything regarding the metabolism, etc...
 
I'm curious too about the ethyl ester sulphate version, hopefully somebody else has some first hand experience and can also share? Comparison to other forms, either in therapeutic or recreational doses, would be interesting.



So, I'm a pretty big fool. I finally had this beast of an addiction beat then a couple weeks ago I went and ordered some Tianeptine sodium. Damnit. WTF is wrong with me?
 
Slower acting than the sulfate apparently albiet more potent
 
My experience with it did not feel more potent, quite the opposite. Most I took was 100mg which I believe is my max sulphate dose ever, however whereas the standard sulphate was sedating to the point that I just had to lie down for a few hours (maybe akin to a "nod", although my experience with opiates is pretty limited), I did not get this at all with ethyl ester sulphate. I actually ended up throwing away the rest of my small quantity of it having decided it was just nothing special, even quite inferior to other forms of tianeptine, and just not worth doing anymore of, especially in light of how new and unstudied it is and therefore possible safety concerns.
 
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