Opioids The Ultimate Opiate Potentiation Thread

[vintageuser]

Need advice!

I have a question and don't want to start a new thread.

I have infront of me 8 Vicodin's. Four are crushed and the others whole. I also have a bunch of 25mg Diphenhydramine pills. I never mixed these two together.

What would hit me stronger and last longer, mixing either 4 pills with 25mg of the Diphenhydramine, or taking all 8 Vicodins? I was thinking of CWE'ing all 8 Vicodin's and taking the 25mg of Diph, but I think I would be pushing it.

I really don't want to die tonight, hah. Thanks!

 

[QuinnMallory]

I've been reading that to potentiate Oxycodone you can use Cimetidine, which is found in the over the counter drug called Tagamet and possibly Zantac. Since Zantac is very similar to Pepcid Complete, do you think I can use Pepcid Complete to receive similar results? I also don't have Benedryl but I have Claratin, would this also work for the use of an antihistamine?

 

[sir_thizzalot]

I'm new to the tagamet thing. I've used tums in the past and they seemed to make 10 and 15mgs of oxy a little better..

This is for tomorrow: Take 200mg tagamet(2 hours after eating at least) 50 minutes before taking 10mg oxy sound about right? Again this is tomorrow so if anybody has advice that'd be great.
Should I take any tums anywhere in there also?

I have no opiate tolerance, haven't done any in a pretty long time.

 

[klauded]

Ok so does Quinine help metabolize Dihydrocodeine? Also There is so much confusion, but after taking Codeine, when I reach my PEAK do I then administer Promethazine to sustain the high? Thanks guys!

 

[2pm2010]

methadone potentation help!!

hy,i've been on done for about 6 month(22 pills of done containing 2.5 mg each pill) and i also take benzo's
right now i have 150 mg of 5 mg nitrazepam and 12 capsules of tranxene of 5 mg pills(capsules)
the question is wich is the best benzo to potentate my methadone that i'm currently on
thx in advance for any response that u give me
thx again,peace and stay safe

 

[splenda]

This is a question more suited for Basic Drug Discussion...

And even then, we don't know which benzo would make you 'higher' because benzos are very subjective and people have different reactions to benzos.

 

[2pm2010]

This is a question more suited for Basic Drug Discussion...

And even then, we don't know which benzo would make you 'higher' because benzos are very subjective and people have different reactions to benzos.

i have a ver high tolerance to nitrazepam/diazepam but tranxene is new for me and i have no tolerance to it
any sugestion would b greatly appreciated
thx in advance

 

[Cane2theLeft]

I think we'll try it out in the opiate potentiation thread for now... OP you should look around the potentiation thread because I bet people with similar experiences have discussed their experiences.

-> The Ultimate Opiate Potentiation Thread

 

[Ds]

hy,i've been on done for about 6 month(22 pills of done containing 2.5 mg each pill) and i also take benzo's
right now i have 150 mg of 5 mg nitrazepam and 12 capsules of tranxene of 5 mg pills(capsules)
the question is wich is the best benzo to potentate my methadone that i'm currently on
thx in advance for any response that u give me
thx again,peace and stay safe

funny u say safe when potnateing ur methadone with a benzo is one of the most dangerous/stupidist thing u can do. i've had friends OD mixing xanax with their methadone, fucked up their dead now., ive had a friend that took a low dose of klonipin and like 15-20mg methadone and had some reaction, he filled with water n some crazy shit, forgot medical term, but he almost died...

fuckin grapefruit juice works good for me, its like people see me sipin a little size of grapefuit juice knows im high lol

 

[Cane2theLeft]

^great advice. Search around and you'll find a lot of ways to potentiate methadone but all of them will raise your tolerance so if you can i would advise just getting on maintenance and finding the right dose.

D's perhaps some form of edema? rhabdomyoliysis?

 

[SubDude]

Is there anyway to get high while on suboxone maintenance?

 

[fm1983]

Is there anyway to get high while on suboxone maintenance?

Are you talking about getting high from the suboxone or other drugs?

How hard it would be to breakthrough the suboxone would depend on how many MG of sub you are daily. Also, I try to abstain from suboxone the day before I take my oxy to help boost the high a bit. I am on (roughly) 3mg daily, and have no problem breaking through when taking an oxy dose. I just took 60mg oxy not too long ago and I have a pretty decent buzz coming on. Also, I took some tagment to potentate it a bit more.

If you are talking about getting high from subs, me personally have never really gotten high from taking them. I do notice though, that when I dose, I get chatty/energized/happier/etc feeling. So I am technically getting a high from it yes, but it's not the opiate high I would long for.

 

[SubDude]

Thanks for the reply. I've tapered down to 1mg but have been on subs for 1.5yrs after 16yrs on methadone. Ive used oxys a few times but I must be careful due to a pending legal case. So I'm really looking for something to use with subs to get high or else synergize the agonist part of bupe.

I've read that St Johns wart and ultram can give subs recreational users a boost but wonder if maintenance patients can get high with this combo or anything else besides benzos/opiates.

 

[Lucid Dreaming]

Using a potentiator for Methadone can be a bit dicey depending on how many milligrams your on and what (if any) other medications are being taken along with the daily Methadone dose.

Using Methadone for recreational purposes especially in persons with little to NO opiate tolerance is like playing Russian roulette and is ABSOLUTELY not a good idea. For starters..depending on how they acquired the Methadone as a recreational user the person who it was acquired from could be facing serious consequences if anything where to happen to the recreational user; like a life time in jail. This should discourage everyone on Methadone for pain or dependency maintenance from EVER giving out there take home doses. As little as 5-10mg in a non tolerant person can be lethal.

Now that I've got that out of the way, as far a potentiating the Methadone there are TWO creditable options. ONE: Drink around 12 ounces of pure grape fruit juice (none of that from concentrate bull shyt) about 20 minutes prior to dosing with the Methadone. After dosing wait about 2 hours then polish off another 12-24 ounces of the juice. This is a increase your peak by about 30-40 percent depending on how high the dose of Methadone is. People that tell you it will rock your world are probably experiencing a combination of the affects plus a placebo type of increase. If you think your going to get higher you probably will convince yourself of such. You will get some results and they will be greater the higher the dose of Methadone as well of the amount of grape fruit juice. Either way be careful. You are trying to increase the effectiveness of an already extremely potent drug.

Method Two: Take some Tagamet. I do not suggest anymore than 400 mg. One 200 mg tablet is the said amount on the box and it suggest not exceeding 400mg in a day. These warnings are in place for a reason people. I tried the Tagamet today about 2 hours ago. Only took one 200mg tablet. I have noticed a small increase (at 77mg of Methadone) and I am aware that the Methadone will last longer through out the day so that is a plus. I don't feel "high" like I would off of some Oxycontin or Morphine and I know that being an opiate tolerant person in dependency treatment means that I will not get high off the Methadone like off other opiates so I don't try.

WARNING: I took 3 off my take homes bringing my dose to about 280mg last year. I went cross eyed and could barely breathe. I was trying to get "high". I didn't realize how Methadone worked. I died that die...but God gave me a second chance and now I am trying to get off the Methadone and the evils of opiate addiction. I used the Tagamet today so that when I sweat in the hot sun the Methadone won't wear off as quickly. Please to everyone out there, do your home work..research the HELL out of Methadone before EVER trying it or trying to increase its effects and certainly don't EVERRR triple dose. Hope this helped at least someone, God speed-Love, Peace, and chicken grease!

 

[raznaruk138]

BLACK SEED OIL (nigella sativa),, this stuff blows gfj, and or tagament away as far as potentiation goes, i took 2 tsp of the oil (with gfj, i drink that every morning regardless) dosed 3/4 of my normal oc dose and it felt a lot better and lasted longer than my full normal dose has in a long long time. normally i will start to feel shitty about 3 - 3 1/2 hours in even with gfj today it was 5 hours till i had any discomfort.

 

[formanchristopher]

i have a ver high tolerance to nitrazepam/diazepam but tranxene is new for me and i have no tolerance to it
any sugestion would b greatly appreciated
thx in advance

As the person above stated, benzos effect everyone differently. I'm replying only because I have history with tranzene. Personally? It would be the nitrazepam for me, although I realize this is way to late by now. Regardless, I needed to subscribe to this thread, and I'm wondering which one you chose??

 

[thelung]

Using a potentiator for Methadone can be a bit dicey depending on how many milligrams your on and what (if any) other medications are being taken along with the daily Methadone dose.

Using Methadone for recreational purposes especially in persons with little to NO opiate tolerance is like playing Russian roulette and is ABSOLUTELY not a good idea. For starters..depending on how they acquired the Methadone as a recreational user the person who it was acquired from could be facing serious consequences if anything where to happen to the recreational user; like a life time in jail. This should discourage everyone on Methadone for pain or dependency maintenance from EVER giving out there take home doses. As little as 5-10mg in a non tolerant person can be lethal.

Now that I've got that out of the way, as far a potentiating the Methadone there are TWO creditable options. ONE: Drink around 12 ounces of pure grape fruit juice (none of that from concentrate bull shyt) about 20 minutes prior to dosing with the Methadone. After dosing wait about 2 hours then polish off another 12-24 ounces of the juice. This is a increase your peak by about 30-40 percent depending on how high the dose of Methadone is. People that tell you it will rock your world are probably experiencing a combination of the affects plus a placebo type of increase. If you think your going to get higher you probably will convince yourself of such. You will get some results and they will be greater the higher the dose of Methadone as well of the amount of grape fruit juice. Either way be careful. You are trying to increase the effectiveness of an already extremely potent drug.

Method Two: Take some Tagamet. I do not suggest anymore than 400 mg. One 200 mg tablet is the said amount on the box and it suggest not exceeding 400mg in a day. These warnings are in place for a reason people. I tried the Tagamet today about 2 hours ago. Only took one 200mg tablet. I have noticed a small increase (at 77mg of Methadone) and I am aware that the Methadone will last longer through out the day so that is a plus. I don't feel "high" like I would off of some Oxycontin or Morphine and I know that being an opiate tolerant person in dependency treatment means that I will not get high off the Methadone like off other opiates so I don't try.

WARNING: I took 3 off my take homes bringing my dose to about 280mg last year. I went cross eyed and could barely breathe. I was trying to get "high". I didn't realize how Methadone worked. I died that die...but God gave me a second chance and now I am trying to get off the Methadone and the evils of opiate addiction. I used the Tagamet today so that when I sweat in the hot sun the Methadone won't wear off as quickly. Please to everyone out there, do your home work..research the HELL out of Methadone before EVER trying it or trying to increase its effects and certainly don't EVERRR triple dose. Hope this helped at least someone, God speed-Love, Peace, and chicken grease!

I was under the impression that Grapefruit juice only potentiated certain benzodiazepines...I'm on MMT @ 95mg daily, and I'm always keeping an eye out for potentiation methods. I'll have to give this a shot, but does anybody else out there have any experience and/or input in regards to grapefruit juice + methadone (MMT or otherwise)?

At my mmt clinic, potentiation meds are huge...mostly people buy and sell Clonidine, Promethazine (tablets and syrup), and of course benzos. this goes on in and around the clinic on a daily basis.

 

[Loserkid]

Grapefruit Juice works for me. It seems to increase the duration and make the high slightly better. Benzo's (although the only one I've ever tried with an opiate is xanax) works alright in my experience too. They tend to change the high a little bit but most frequently for the better.

^ I've heard this was dangerous. Grapefruit juice slows down the way your body breaks down the xanax. Wich could allow it to build up to dangerous level in your bloodstream.

 

[raznaruk138]

the lung, try Black seed oil, I am fairly certain you will notice marked increase in effects when talking 2tsp with your dose.
I have tried the grapefruit juice and tagament, and both seem to potentiate my oc to some degree,very minor, but this black seed oil REALLY potentiates, like many have said the best potentiation of a drug is more of that drug, well, here is an oil that contains thymoquinone that has analgesic and anti-inflammatory properties and works on opiate receptors, the nice thing here is its 100% legal, good for you, and works very well.

 

[goa]

doxylamine is one of the best IMO, really brings the nod on and makes it more intense, and of course weed