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Opioids The Ultimate Opiate Potentiation Thread

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lozgod said:
I may of found the ultimate potentiater. Low dose suboxone and your DOC. Low enough dose to occupy say 30-40% of your receptors. Like 1-3mgs depending on tolerance. Then the DOC occupies the rest. I swear I can take 4mgs in the morming and 12 hours later take 1 30mg roxi and its like I did 3 or 4. Might only work for those with very high tolerances like mines but I might have to say I swear by it.
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It don't work for me... low dose subs 24 hrs prior... then some oxys work ok but not the combination.
 
The best potentiator is an empty stomach. Recently filled with an opiate of choice and a 50/50 mix of 8 oz grapefruit juice and 8 oz water along with 50mg Benadryl.
 
damn straight....empty stomach.

I used to never shoot up until I was sure my stomach was empty and I could feel it gurgling telling me im hungry.....it would make the rush SOOOOOO much more euphoric, and make it last longer in general.

Now that im clean, every time I get that gurgly feeling in my stomach telling me im hungry, it reminds me of opiates and I start to salivate at the thought of old memories....
 
DoseYouAll said:
Promethazine most definitely give the pod tea high some legs! Taken 30 minutes after I feel the effects of tea, a promethazine pill makes the high a lot more noddy and longer lasting. Nice!
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Yes promethazine is excellent....but they make you feel ropey the next day I found.

And thats on a relatively small dose...around 50 to 70 mg.
 
Hi Just detoxed from opiates and still strugglin..

Hi :) im am new at all of this - the whole thread - posting thing, so i hope i am i n the right place? :o
I am just detoxing :p - day 3 GREAT and i am surprised i have the energy to type. I came onto this site hoping to meet others lke me that are kicking the habbit slowy!! 8o Can anyone tell me where I go to talk to others like myself>?

Thank you
<3
 
FoxyChix said:
Hi :) im am new at all of this - the whole thread - posting thing, so i hope i am i n the right place? :o
I am just detoxing :p - day 3 GREAT and i am surprised i have the energy to type. I came onto this site hoping to meet others lke me that are kicking the habbit slowy!! 8o Can anyone tell me where I go to talk to others like myself>?

Thank you
<3
Click to expand...

Try using the search engine and posting in a support thread. There out there. Congrats n good luck!
 
Ive been on oxycodone 30mgs 6x's a day for almost a year. And recently do to the shortage of oxycodone 30's where i live. My doctor switched me to 8mg dilaudid 6x's a day instead. And to be honest it does not seem to help the pain nearly as much! I no dilaudid is much stronger, but ive been on it for 2 months now. And it still isnt working nearly as well. And as a youth i experimented with drugs in all forms, but until this switch i HAVE NOT shoot up anything till this switch!! I was in such pain I had no chose but to shoot some dilaudid to kill the pain! When i was on my oxycodone I took it as perscribed, except for once in a blue moon snorting one. And now when im in SEVERE CHRONIC PAIN I have to shot some dilaudid to get the pain to stop. when in the past if i was in that much pain i would possibly have to snort 2 oxycodone, and take a couple perks. Its scaring me to death that because of the DEA cracking down on south florida with the oxycodone 30's(or roxicodone) that I may become addicted to the shooting!!!! Even though its only when im in horrible pain that i do shoot( FOR NOW ) it really worries me! Is anyone out there going threw this? Or has anyone felt the roxicodone helped more than the dilaudid? And if so will I eventually just get used to the dilaudid and not have to abuse it to get relief? Any suggestions, word of wisdom, or suggestions would be greatly appreciated!!!!!
 
Just wanted to say that I saw a thread on here the other day about Tussionex and how the antihistimine in it potentates the effects of Hydrocodone, and it's the absolute truth. I have a pretty low tolerance, as I'm an infrequent user, but holy cow!! o_O Took a dose of Tussionex and a Lortab 7.5... that was nearly six hours ago and I'm still feeling it! Highly recommended. =D
 
What antihistamine to get for opiate use

Hi i have the choice between diphenhydramine and promethazine, firstly which one adds the most sedation and/or potentiation, and secondly what kills the itch more?

thanks to any input :)
 
i've never used promethazine myself but by seeing other peoples reports with it, I think it would be superior to diphenhydramine. (i use hydroxyzine myself which i feel is the best antihistamine to mix with opiates) too bad you dont have access to that :\
 
all first generation antihistamines will add to the sedation of the opiates, so be weary of that; in higher doses some will cause delerium. the first gen anti-histamines i've used (have access to) are promethazine, diphenhydramine and doxylamine succinate - all work great.

the second generation antihistamines have no sedation as a side effect. some of these include zyrtec, allegra and claritin.

http://www.allergyescape.com/best-antihistamines.html

that site includes a generous list of both 1st and 2nd gen antiistamines, listing each uses, common side effects, rare but serious side effects, advice on dosing and a list of contraindications some anti=histamines may have with other pharmaceuticals.
 
I find Doxylamine and DPH work great for stopping histamine release, and also adds a nice sedation to the high.
 
I think promethazine and diphenhydramine are about equally as useful when it comes to enhancing opiates, but, at least in my experience, promethazine is a bit more sedating than diphenhydramine...which is sometimes what you want (it really enhances the nod of morphine and hydromorphone). On the other hand, if you want to stay more awake with your opiate high, I would recommend diphenhydramine or doxylamine, its also a lot easier to get...at least in the USA.

As far as knocking down the opiate itchies, hydroxyine and diphenhydramine are probably the best ones. Leftwing is very right though, all the first generation ones can cause nasty side effects of their own. If you're using antihistamines for enhancing opiates, start low in dosages and remember that they are drugs of their own. :)
 
I've always liked doxylamine to pair with my opiates as i feel it has less unwanted side effects than the other first gen antihistamines; in my opinion it provides much more sedation and with less of that really strong dysphoric feeling that DPH is known for in higher doses especially
 
Promethazine is a lot stronger than diphenhydramine, however it causes a lot of weird dysphoria and such.

Overall I think hydroxyzine is considered the best for opioid potentiation. I have also heard that doxylamine is good for this purpose (though I've never taken it for any other purpose than to sleep.)
 
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