What ratio would you use for 4-ho-met instead of 5-meo-mipt
4-HO-MET is a little less potent. I would use perhaps 100:25:1
I actually have in my head that a dose is 20mg but wiki lists 15mg as a high “common” dose (I’ve not tried it). If it is 20, then I would go for 100:25:1.4.
[M]iPT should not be combined with entactogens. I believe it is a triple reuptake inhibitor while also having speculation around it's MAOi activity
I definitely do not think MiPT has meaningful MAOI activity. I think it is possible that there is some reuptake inhibition but I have not had any problems using it in combinations. I would prefer to use another tryptamine if I had one, to rule this uncertainty out.
I had the following mixture on friday
5-MeO-MiPT 5.2 mg
5-APB 35.0 mg (not 5-MAPB but relevant due to similar properties)
2-FMA 23.8 mg
2C-B nasally as desired (15mg over 6h)
The aim was to have a light roll (no comedown wanted) with intensity provided by the psychedelics. I wanted to have ketamine too, for adding intensity, but it got confiscated.
Overall it was very successful; there were some pretty solid effects, not overly intense (I prefer lower intensity experiences), and no comedown. 2C-B brought ample visuals.
Is the 2-fma necessary if the goal is more towards enhancing psychedelic effects and not partying/trying to mimic mdma?
I think it is, because it balances the monoamine release. This allows for a lower dose of 5-MAPB for the same intensity, increasing the ratio of effects to side-effects. I have had MDAI (a highly selective serotonin releaser) with psychedelics before (25I, 2C-B) and generally I did not enjoy it. I found it made the experience darker. For this reason I would aim for a low dose of empathogen with balanced release.