• 🇬🇧󠁿 🇸🇪 🇿🇦 🇮🇪 🇬🇭 🇩🇪 🇪🇺
    European & African
    Drug Discussion

    Welcome Guest!
    Posting Rules Bluelight Rules
  • EADD Moderators: Pissed_and_messed | Shinji Ikari

The EADD a trifle annoyed thread v. I bet that smarts a bit

It is an interesting debate that im also curious about. At one point ut was a proven thing that incidence of genetic disorders predisposing to increased testosterone is significantly higher among prisoners. Might not be the sole reason for violence but testosterone has a proven and testable effecton the brain (among other things)
I would never do roids though. I love my testicles too much
 
englandgz74 said:
Its actually a much debated subject re. "roid rage" and whetherthe drugs tthemselves cause aggressive outbursts of if the increased physical presence mearly enable inherent violent tendencies to come to the fore. I guess its different in everyone. Often of a 10 stone arsehole takes gear and becomes 15stone......he just becomes a much bigger arsehole. I know guys who are literally inhumanly big and strong, use alsorts and wouldn't hurt a fly.....I also know guys who use nothing who are sadistic bastards. Its something I've researched a lot though and the scientific/medical community can't seem to decide if increased androgen levels are responsible or not. I suspect its a complex medical/physiological interaction that has many facets and pigion holing people just isn't possible......something I'm interested in though.
Click to expand...

Might just be that a lot of people who use steroids are image obsessed and / or obsessed with power.. and spending all day in the gym and admiring the god that they are boosts the ego to unstable conditions.. The slightest glimmer of possible disrespect is enough to send a man who believes he is a god among men into a frenzy that will re-establish his superiority in the only way he knows how.

raas said:
Eve you shouldn't comment on something you clearly know nothing about. Weed is meant to be eaten, I don't want to explain all this because it bores the forum and goes off topic
Click to expand...

No it's not.
 
Last edited:
Huh?

Don't what? If you think that post is what i think you think that post is you're wrong..
 
4 more days and ill be free. well, free from this stress that is. more shit to come im sure
 
mydrugbuddy said:
Evey, i dunno if you are even talking to me at the moment, but dont take these things so personally, this is very much a forum full of pedants, and people who know more than you, (who ever you are, with just a few exceptions, some people had such incredible depth and breadth of knowledege, well ouside most peoples normal range that it would seem very churlsih to correct one of those legendary posts by Amanatadine, or Babylon Boy, Or Knock, for example.) and who seem out to to prove it sometimes.... Although it is annoying to be publically corrected, at least you wont carry on repeating the same false statements in the future.

Raas, you're not being rude, disrespectful and condescending. Many people do eat weed, preceicely because it can be more "trippy" when consumed that way. "Eve you shouldn't comment on something you clearly know nothing about." was a bit of a rebuke though imo.
Click to expand...

Raasy n I have already discussed this in private. It doesn't need re-discussing. I'm aware that weed is ate for various stuff - as was shown on Coronation Street awhile back but to get high it is smoked n can cause hallucinations as Raas himself said.

Also I have never tried to "correct" Knock or Amanadine - they were friends n im well aware of their knowledge. I talked with Ama a lot in PM after Knock passed. I'd have no desire to disrespect either of them that way.

Now can we please drop this as it was between Raas n I n doesn't need bringing it back n fueling further drama. Thanks :)

Evey
 
I even make chocolate treats from it. If I remember this was black. One was enough to blow you into hyperspace =D

NSFW:
PICT0025.jpg
 
dan88 said:
I sometimes eat weed to get high..
Click to expand...

Do you???? What's it like? The experience I mean. And do you eat it in something like a cake????

kate said:
I even make chocolate treats from it. If I remember this was black. One was enough to blow you into hyperspace =D

NSFW:
PICT0025.jpg
Click to expand...

That looks nice bi'd like to try weed to be honest.

I guess I was wrong to think it mustn't be ate. I've learnt a lot from Bluelight.

Evey
 
I've no wish to get involved in any arguments but the issue of ROA whether it comrs to recreational drugs or medicines is mainly about onset of effects and bioavailability (although there are some other complications such as first pass metabolism and enzyme activity in the stomach and liver etc.) Generally if a substance is smoked it reaches the brain very quickly via the small capillaries in the lungs I to systemic circulation. In fa t it reachestthe brain almost as fast as IV injection. This bypass of first pass metabolism can have a profound effect on some drugs that have a very poor oral bioavailability (e.g. heroin and morphine) but for some drugs (most benzos for example and also methadone) they have such a high oral BA that smoking or injecting is unnecessary. There is also the issue of "rush" tbat people enjoy which is really more a function of the drug hitting so fast rather than any mythical part of any particular ROA.

While I'm not an expert on weed (and don't claim to be). I understand thatit has a high oral bioavailability so one can get very high from oral ingestion and the primary reason it is smoked is that it hits faster.

While I do know a bit about pharmacology and the workings of the human body, like I say I'm not a cannabis expert as personally I hate the stuff but iI would be interested to know from others who do know a lot about weed what are the main differences between eating and smoking other than onset of action. Does anyone know comparable BA figures or enzyme interactions, first pass metabolism, etc..... Just curious that's all

Edit.....forgot to add that there is also the issue of base versus salt in the "smokeability" of a substance as most people know generally only a freebase (non-salt) of heroin or cocain (crack) can be actually smoked as the hydrochloride salt does not vaporise at a low enough temperature to be smoked...also the reason why diamorphine base needs the addition of an acid to be injected as the base isn't water soluble. I know most people already know this but thought it worth adding (can you tell I'm bored today?...Lol!)
 
Last edited:
Oral THC has low bioavailability cos of 1st pass metabolism (around 10% (of IV)) and it is unpredictable in absorption (finnicky with lipids). Also the plasma concentration obviously peaks much later than with smoking. But notably, when you eat yer THC, the psychoactive metabolite 11-HO-THC will have 100% bioavailability compared to the 20% BA you get when smoking.
 
lurching said:
Oral THC has low bioavailability cos of 1st pass metabolism (around 10% (of IV)) and it is unpredictable in absorption (finnicky with lipids). Also the plasma concentration obviously peaks much later than with smoking. But notably, when you eat yer THC, the psychoactive metabolite 11-HO-THC will have 100% bioavailability compared to the 20% BA you get when smoking.
Click to expand...

That's very interesting thank you. As I mentioned it can get complicated when comparing different ROAs. So really your saying that while THC as a whole has a lower oral BA, the metabolite responsible for most ofthe psychoactive effects actually has a higher oral BA....

I was hoping someone like yourself with an excellent knowledge of cannabis metabolism would be able to answer it...thanks again.
 
Incidentally, neversickanymore, felonious monk and myself have been discussing for months the creation of a resource for BL regarding overdosing and the ttreatment of overdoses and what to do versus what not to do.

Due to the nature of my profession and having seen and helped treat numerous od s FM asked me to take the lead in getting some stuff down and we will bopefully try to edit into a bare bones/all gou ever needed to know thread about recognising, treating and surviving an overdose.

I have posted a rough guide from an emergency medicine point of view but would love it if people could check it out and add anything constructive that they might have to say on the subject.

The link is..

.http://www.bluelight.org/vb/threads/737345-Workshop-Help-BL-create-an-Overdose-Resource-Sticky

Its a sticky in the drug culture forum....please check it out. Our goal is to save someone's life at the end of the day and the info in this thread could help you do just that.

Thank you and god bless all.
 
Eveleivibe said:
Do you???? What's it like? The experience I mean. And do you eat it in something like a cake????



That looks nice bi'd like to try weed to be honest.

I guess I was wrong to think it mustn't be ate. I've learnt a lot from Bluelight.

Evey
Click to expand...

I always enjoyed eating weed, though have maybe done it about ten times in my life compared to smoking it prob far too fucking much. It's a very different experience, the most intense one was eating hash and falling into what I can only describe like eleven years later as a 'music tunnel' and everything having a 2D, bright, cartoonish quality to it, especially outside. Fairly visual at times, and other times it's just like being really stoned for a long time. Fun, and you can cook loads of stuff with weed. Have had brownies, chai tea, egg and bacon sandwiches (lot of people make weed butter and then use that to cook with) etc.

Vaguely annoyed because the codeine is wearing off, I can't take any more paracetamol today, and Ibuprofen gives me asthma attacks so I'm stuck feeling crap for a while. It's not the end of the world but hey.
 
Yeah, tis what I did earlier today but only had one pack, and can't really afford to order bottles. Sucks a bit but I'll live, I assume!
 
snolly said:
Vaguely annoyed because the codeine is wearing off, I can't take any more paracetamol today, and Ibuprofen gives me asthma attacks so I'm stuck feeling crap for a while. It's not the end of the world but hey.
Click to expand...

If you did a CWE right, I believe a maximum of 1g of paracetamol per 100ml is soluble. Or am I missing something, is there some other reason you can't take any paracetamol?
 
You must log in or register to reply here.
Top