PsychedelicDoctor
Bluelighter
- Joined
- Jan 3, 2009
- Messages
- 346
oh word, thanks for that. i'm up in the air as to whether or not i want to open this can of worms.
The Big & Dandy Methoxetamine Thread - 5th Dose (you took too much, seriously)
- Thread starter any major dude
- Start date
- Status
oh word, thanks for that. i'm up in the air as to whether or not i want to open this can of worms.
johannes kreisler
Bluelighter
the fast comeup also adds to K's addictiveness. didn't try IM but even plugging takes some time and is quite gradual and not rushy with MXE. thats also a little bit of a problem with MXE as you might like the stuff very much when you're on it and lose track of consumption. like: "oh! time to put another log in the fire!"...and the last one isn't even burning yet...and you're too high/confused to remember or simply lost track of time.
DwayneHoover
Bluelighter
GREAT new word, thanks!
DiZzyBonne
Bluelighter
- Joined
- Dec 10, 2009
- Messages
- 420
I haven't tried DXM, but I feel it did produce a similar effect when walking to ketamine. However, it wasn't as pronounced as it is on ketamine (I found it more fun to move and walk around while on K.) I was on a heavy dose of MXE (I'm usually on a heavy dose of K as well) and I found it way more confusing than K. In fact, I actually found it to feel a lot like the (+) isomer of ketamine (hereon typed out as (S) ketamine,) in the sense that it's less sedating, but a lot more confusing. However, it's even more confusing and even less sedating than (S) ketamine.
Even though I always preferred (S) ketamine due to the added confusion, and MXE was pretty much (S) ketamine, it wasn't as sedating which is what makes K my favorite. MXE comes in a really close second though.
The other downside to MXE is the after effects, which can linger for as long as two hours. The effects themselves last for about an hour and a half for me, which I liked, but the after effects are just really annoying.
Marauder
Bluelighter
I have been using MXE daily for about a month. I dose 4-5 times a day mostly insufflated but prefer IM. I do 10-15mg bumps every few hours. No crash/ill effects except the days seem to last forever but overall weeks seem to fly by.
Nicotine has stopped working (no rush whatsoever) and smoking went down 90% - No cravings for any other drug whatsoever.
Nicotine has stopped working (no rush whatsoever) and smoking went down 90% - No cravings for any other drug whatsoever.
psood0nym
Bluelighter
Though MXE is not ketamine, here again is a reminder that frequent dissociative use is probably bad for you. If you need to use it a lot over a short period to work through some specific issue, or if you do it once or twice a month for kicks, fine, but chronic use may very well be doing damage.
DwayneHoover
Bluelighter
^ Yea, even though there's no indication of the magnitude or of connection to specific functional deficits... "reduction of frontal gray matter volume" doesn't really sound like something I want to be signing up for at the moment.
Survived Abortion
Bluelighter
Yes, it definitely does this. I touched upon this in an earlier post about how it destroys my energy. It feels the very same kind of energy drain that ketamine used to produce in me, although it's much worse with MXE for some reason.
Although this is all purely speculative, I would make the guess that this is somehow related to a rapid increase in cellular metabolism. This is what it feels like to me. It's almost as if it causes the energy conversion reactions inside your cells to excite and increase in rapidity markedly. This probably is happening initially at the NMDA receptor sites as a result of the changes in signal resolution, and then cascading through AMPA receptors and the rest of the brain and body. The brain uses a lot of glucose during normal operation anyway - in comparison to the body as a whole - so this wouldn't suprise me.
some people may find this disgusting, but anyway:
yesterday evening I plugged 30ml of a (ice cold) 50:50 vodka/water solution with 1mg/ml MXE in it (I usually prepare 100ml-vials of that solution for sublingual use on a night out). I'm pretty experienced with plugging various substances and never had bad reactions.
the experience went like expected but this time the after effects were truly vile. after the MXE wore of I began to feel pain in my bowels. felt like a had to go to the toilet badly - which I did a dozen times during the night without much results. I was suffering the whole night, finally soothing me with a litre of camomille tea and 0,5mg of lorazepam, which gave me 2h sleep (had to get up early).
in the morning I could finally release some gas and some bloody mucous.
24h after consumption it's way better but I still feel not right. (afraid to check if there's still blood..)
This sounds to me like the colic I mentioned earlier in this thread. I have had a recurring problem with colic in various forms with dissociative use. It does seem to cause spasms of the biliary tract in particular, which is excruciatingly painful (see Biliary Colic). I actually had to have my gall-bladder removed in 2007 following a year of heavy ketamine abuse and cholecystitis. It is a horrible thing to endure, and a completely terrible thing to have to resort to removing a body part to cure.
Hyoscine butylbromide is an anti-spasmodic which will temporarily relieve moderate cases of colic. You can buy it over the counter. That is probably the best temporary aid for those coliky pains associated with dissociative use, but the best long-term solution is to not use too often. *Note: opiates will make your colic worse, so definitely don't resort to opiate painkillers if you're having those pains.
johannes kreisler
Bluelighter
...wanted to try if smoking this stuff works. 20mg through 'the machine' and 
well. it does. immediate onset, but still a gradual comeup.
at t+30 I snorted 10mg on top and smoked a little bit of weed. juggling works and is awasome, as is minimal techno in the background ( http://www.youtube.com/watch?v=dAuN3bgUjJQ ). "some time later" 12mg sublingual. that's where I am now; time is severely distorted. and I must admit that the stuff is quite fiendy. I promise myself to stop now. I think the fast onset with smoking makes this much more addictive...gotta stay clear of that in the future. I didn't plan a serious experience but I feel a little like the drug is sucking me in.
anyway: I feel pretty good. very energetic, optimistic, even joyfull. whatever there may come. body feels great despite the fact that I'm quite sick actually. the drug gives me the feeling that it has the power to change my life, make me a better person, liberate me. this applies to a few drugs but with MXE there's a strange seriousness in this claim. like it's changing you (for the better) without you even noticing it. this is frightening on the other hand. MXE is still a quite addictive substance. is there fear of MXE's grip when you're on it? no. it's just on that quality level that you might be inclined to say "well, why not be addicted to this stuff? feels that good and healthy."
MXE is for sure one of the best psychoactives I ever touched but it also demands more respect and humbleness than most psychoactives I know. it's a mighty drug.
well. it does. immediate onset, but still a gradual comeup.at t+30 I snorted 10mg on top and smoked a little bit of weed. juggling works and is awasome, as is minimal techno in the background ( http://www.youtube.com/watch?v=dAuN3bgUjJQ ). "some time later" 12mg sublingual. that's where I am now; time is severely distorted. and I must admit that the stuff is quite fiendy. I promise myself to stop now. I think the fast onset with smoking makes this much more addictive...gotta stay clear of that in the future. I didn't plan a serious experience but I feel a little like the drug is sucking me in.
anyway: I feel pretty good. very energetic, optimistic, even joyfull. whatever there may come. body feels great despite the fact that I'm quite sick actually. the drug gives me the feeling that it has the power to change my life, make me a better person, liberate me. this applies to a few drugs but with MXE there's a strange seriousness in this claim. like it's changing you (for the better) without you even noticing it. this is frightening on the other hand. MXE is still a quite addictive substance. is there fear of MXE's grip when you're on it? no. it's just on that quality level that you might be inclined to say "well, why not be addicted to this stuff? feels that good and healthy."
MXE is for sure one of the best psychoactives I ever touched but it also demands more respect and humbleness than most psychoactives I know. it's a mighty drug.
phatass
Bluelighter
I'm a big Ketamine fan, i used to do 3-4 grams per day for about a year... i'm getting some MXE, and i want to M-hole... how much will i need taking into account that i havn't done K in over a year...
sekio
Bluelight Crew
Try 3/4 of your normal ketamine dosage and work your way up from there. Don't redose in the initial few trials, MXE lasts much longer.
Xamkou
Bluelighter
Laughing at how much of a problem I av with this chemical
Xamkou
Bluelighter
Lkgyu
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pharmakos
Bluelighter
sekio's advice could be a little reckless. 3/4 of your normal K dosage could be way too much MXE if your tolerance has dropped considerably over the last year, especially considering you used to do 3-4 grams a day...
i say start with 50mg-100mg and work up from there if you need to. 100mg would probably be okay for your first go, since you're looking to M-hole, but if you wanted to start lower that might be a bit more responsible of you.
sekio
Bluelight Crew
I'm talking about a single bolus dose when I refer to "3/4 your normal dose". So if you take e.g. a dose of 200mg ketamine to feel good, try 150mg mxe. Of course don't do 3 grams a day and don't do it with the same frequency you do K.
Of course, methoxetamine responds dfferently in everyone. 50-100mg starting doses seem to be common.
Of course, methoxetamine responds dfferently in everyone. 50-100mg starting doses seem to be common.
pharmakos
Bluelighter
^^^ lots of people in this thread have said that they don't go above 50mg. i suggested 50mg-100mg to him based on his past K use.
the toad
Bluelighter
I agree with the 50-100mg... I typically give first timers 50mg... people with K experience that want a strong dose 80-100...
My MXE Manifesto- Bunk BS to Beautiful Base
So, as prolly a few of you who follow the MXE scene are aware, there is a serious issue with product purity going around right now.
Is it salty or saline-like? Is it bitter? Is it sandy or crystalline or floury or fluffy? Is it yellow, off white or white like driven snow?
Dammit. We just want reliably pure MXE... But for the last three attempts a salty, MSG-like, hypertensive mix of junk has been all that has made it to us.
Analysis of this material shows that the organic extractable fraction is demonstrably MXE, but that the material contains LOTS of inorganic salts that are silent on NMR and MS. That way, the NMR or HPLC-MS looks clean, but on a per mass basis the recent materials received are laughably weak due to the inclusion of inorganic salts in the final products (intentional for purposes of profit, or due to ineptitude, who knows?).
Basically, the "bunk" MXE is salty, off-white/yellowed, granular or crystalline and sometimes has a weak, odd odor. Great MXE is fluffy, white, bitter like an amine should be and NOT salty.
So, this is the tale of how frustration at impure MXE material was overcome in a shockingly successful manner-
Read on for details (tl;dr = basify, extract into organic, remove solvent, vape, smile):
So, as mentioned above, the last three attempts at MXE acquisition were failures in that US domestic vendors are flogging impure, bunk junk.
It was first ascertained that the MXE was clean of appreciable organic impurities. It was secondly determined that the MXE material was contaminated with inorganic salts, and that the material provided VERY negative outcomes upon oral ROA. The insufflated ROA was also attempted once, and once only. Negative outcomes included soberness, hypertensive incidents, headaches, tinnitus and frustration.
* So, weak, yellow, granular, salty MXE was dissolved in distilled water and warmed until dissolved and the aqueous solution was clear and slightly yellow.
* Then sodium hydroxide was added, which immediately turned the aqueous solution opaque with suspended solids (insoluble MXE base).
* Hexane was added and the container shaken vigorously.
* The aqueous layer become less opaque (as MXE base moved into the hexane layer) and a nasty brown interface layer developed.
* Hexane layer was removed to a new container, and the aqueous layer was reextracted with another amount of hexane.
* Hexane layers were combined and the solvent was removed by evaporation until a minimal amount remained.
* A tube was tared, 1/5 ml of remaining hexane solution was added and the solvent removed by evaporation. The tube was reweighed and it was determined that ~21 mg of oily material was left in the glass tube after hexane was blown off.
* Remaining hexane was aliquoted into tubes and dried down in the same fashion.
=> As a ROA, a tube was heated with a lighter and the residue was vaporized/inhaled (~1/3 tube per session = ~7 mg).
Effects of vaporized MXE base, compared to MXE powder:
* Timeline: Effects manifest within ~1-5 minutes, and peak by 15 mins. It is STRONGLY suggested that at LEAST 20 minutes waiting/assessment period is inserted after each robust inhalation, or couple of weak inhalations... Effects can compound quickly to produce an overwhelming experience. Effects do not last as long as other ROAs, peak hits for about 20 minutes, appreciable comedown is achieved within 1 hour, and by 2 hours it's done.
* Quantitative effects: WTFROFLMAOBBQ. I'd say it's a tad bit more potent than what most folks are used to, when they go for a MXE experience. And by "tad bit" I mean "a million metric tons". For a frame of reference, remember that ~20 mgs makes it into the tube for vaporization. This is enough for ~3 powerful (but brief) sessions. Thus, ~6-7 mg MXE base vaporized will put someone on their ass, even with tolerance.
* Qualitative effects: COMPLETELY different than oral or insufflated. Vaporized MXE base is very rushy, manic, colorful, pushy and stimulating. There is no hole, at least from what we've seen... When one treis to get close to the M-hole zone the other effects of vaporized MXE (rushy, pushy, dopaminergic mania) come to the forefront and take over- preventing a hole from manifesting. It's also less visual, in that CEVs which are often experienced with oral and insuff MXE are not present for vaporized MXE.
So, although we're still hunting for the real, pure MXE... We can at least rest easy in the sure knowledge that our last three purchases of MXE baby do not have to be thrown out with the inorganic bathwater impurities. They will be converted to base and used for experimentation instead.
Up next in the utilization of MXE base is to add a few drops of vinegar to a tube containing ~20 mg MXE to dissolve and form the acetate salt in situ, followed by dilution into water and oral ROA. Will this provide the oral effects (Vaping MXE base gets exhausting after awhile) while avoiding the goddam toxic inorganic junk? We hope so!
So, as prolly a few of you who follow the MXE scene are aware, there is a serious issue with product purity going around right now.
Is it salty or saline-like? Is it bitter? Is it sandy or crystalline or floury or fluffy? Is it yellow, off white or white like driven snow?
Dammit. We just want reliably pure MXE... But for the last three attempts a salty, MSG-like, hypertensive mix of junk has been all that has made it to us.
Analysis of this material shows that the organic extractable fraction is demonstrably MXE, but that the material contains LOTS of inorganic salts that are silent on NMR and MS. That way, the NMR or HPLC-MS looks clean, but on a per mass basis the recent materials received are laughably weak due to the inclusion of inorganic salts in the final products (intentional for purposes of profit, or due to ineptitude, who knows?).
Basically, the "bunk" MXE is salty, off-white/yellowed, granular or crystalline and sometimes has a weak, odd odor. Great MXE is fluffy, white, bitter like an amine should be and NOT salty.
So, this is the tale of how frustration at impure MXE material was overcome in a shockingly successful manner-
Read on for details (tl;dr = basify, extract into organic, remove solvent, vape, smile):
So, as mentioned above, the last three attempts at MXE acquisition were failures in that US domestic vendors are flogging impure, bunk junk.
It was first ascertained that the MXE was clean of appreciable organic impurities. It was secondly determined that the MXE material was contaminated with inorganic salts, and that the material provided VERY negative outcomes upon oral ROA. The insufflated ROA was also attempted once, and once only. Negative outcomes included soberness, hypertensive incidents, headaches, tinnitus and frustration.
* So, weak, yellow, granular, salty MXE was dissolved in distilled water and warmed until dissolved and the aqueous solution was clear and slightly yellow.
* Then sodium hydroxide was added, which immediately turned the aqueous solution opaque with suspended solids (insoluble MXE base).
* Hexane was added and the container shaken vigorously.
* The aqueous layer become less opaque (as MXE base moved into the hexane layer) and a nasty brown interface layer developed.
* Hexane layer was removed to a new container, and the aqueous layer was reextracted with another amount of hexane.
* Hexane layers were combined and the solvent was removed by evaporation until a minimal amount remained.
* A tube was tared, 1/5 ml of remaining hexane solution was added and the solvent removed by evaporation. The tube was reweighed and it was determined that ~21 mg of oily material was left in the glass tube after hexane was blown off.
* Remaining hexane was aliquoted into tubes and dried down in the same fashion.
=> As a ROA, a tube was heated with a lighter and the residue was vaporized/inhaled (~1/3 tube per session = ~7 mg).
Effects of vaporized MXE base, compared to MXE powder:
* Timeline: Effects manifest within ~1-5 minutes, and peak by 15 mins. It is STRONGLY suggested that at LEAST 20 minutes waiting/assessment period is inserted after each robust inhalation, or couple of weak inhalations... Effects can compound quickly to produce an overwhelming experience. Effects do not last as long as other ROAs, peak hits for about 20 minutes, appreciable comedown is achieved within 1 hour, and by 2 hours it's done.
* Quantitative effects: WTFROFLMAOBBQ. I'd say it's a tad bit more potent than what most folks are used to, when they go for a MXE experience. And by "tad bit" I mean "a million metric tons". For a frame of reference, remember that ~20 mgs makes it into the tube for vaporization. This is enough for ~3 powerful (but brief) sessions. Thus, ~6-7 mg MXE base vaporized will put someone on their ass, even with tolerance.
* Qualitative effects: COMPLETELY different than oral or insufflated. Vaporized MXE base is very rushy, manic, colorful, pushy and stimulating. There is no hole, at least from what we've seen... When one treis to get close to the M-hole zone the other effects of vaporized MXE (rushy, pushy, dopaminergic mania) come to the forefront and take over- preventing a hole from manifesting. It's also less visual, in that CEVs which are often experienced with oral and insuff MXE are not present for vaporized MXE.
So, although we're still hunting for the real, pure MXE... We can at least rest easy in the sure knowledge that our last three purchases of MXE baby do not have to be thrown out with the inorganic bathwater impurities. They will be converted to base and used for experimentation instead.
Up next in the utilization of MXE base is to add a few drops of vinegar to a tube containing ~20 mg MXE to dissolve and form the acetate salt in situ, followed by dilution into water and oral ROA. Will this provide the oral effects (Vaping MXE base gets exhausting after awhile) while avoiding the goddam toxic inorganic junk? We hope so!
sekio
Bluelight Crew
I'm not going to elaborate why here, but I think you're full of shit. No inorganic salt I know of will negate a dissociative trip, nor are things like MSG psychoactive (let alone inorganic).
That said, it's good to have a data point on vapourised ROA.
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