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The Big & Dandy Methoxetamine Thread - 5th Dose (you took too much, seriously)

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^i guess this is due in part to the fact that there are different types of tinnitus. some tinnitus comes from central (mental) issues. other cases are peripheral and caused by issues with the inner ear (cochlea). the peripheral cases are the ones where the tinnitus could be similar to phantom limb pain.

i am hoping, optimistically, that the tinnitus caused by mxe is a central effect. maybe an aural hallucination in a way.
on the other hand the tinnitus could be a sign that the mxe is damaging your inner ear.
 
twelvesevndi said:
^i guess this is due in part to the fact that there are different types of tinnitus. some tinnitus comes from central (mental) issues. other cases are peripheral and caused by issues with the inner ear (cochlea). the peripheral cases are the ones where the tinnitus could be similar to phantom limb pain.

i am hoping, optimistically, that the tinnitus caused by mxe is a central effect. maybe an aural hallucination in a way.
on the other hand the tinnitus could be a sign that the mxe is damaging your inner ear.
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I think the most annoying part is that your sensitivity to sound is cranked up to 11 on MXE. The invasiveness of the tinnitus it causes is probably down to that. But something has still caused that tinnitus to appear in the first case, and I'd love to know what.

Also, the deafening loudness of MXE tinnitus really feels downright painful sometimes. Can the loudness of the tinnitus cause physical damage in its own right?
 
^^I don't think it has to do with damage to the inner ear. I looked up neramexane after you mentioned it above. Neramexane is related to memantine, and memantine is an NMDA antagonist used for alzheimer's. As I understand it, memantine works by improving the signal-to-noise ratio of the NMDA recptor in cases where there is excess glutamate stimulating the neurons. Since the NMDA receptor is a kind of coincidence-detector, the drug allows coincident signals that would otherwise be buried in the noise-floor to be heard within an acceptable dynamic range.

Presumably, dissociative drugs like MXE and ketamine do the same thing. If tinnitus was due to an actual increase in noise of this neuronal complex - reducing the dynamic range of the auditory system - it would presumably apply equally to all the senses. This goes with what I was saying about tinnitus being a state in which the brain is hearing noise that it normally filters out.
 
Cyanoide said:
I had my first negative experience with MXE yesterdy.

First I took 50 mg 2C-C which was a huge disappointment. The come up was as usual, but the actual trip lasted only for about an hour and suddenly dropped very rapidly (I've used the same batch not too long ago, and my trips are usually 4 hours). Then I decided to continue the evening with MXE. First I took 40 mg. This felt good, but not that strong. I continuted with two redoses, 35 mg and 40 mg so altogether 115 mg MXE. The result was a strong confusion and disorientation, but absolutely no euphoria, no joy, nothing enjoyable. I felt cold and empty inside. Almost like I had no feelings at all. It's a good batch, I usually use it in the 60-80 mg range and have had great trips. I tried to boost the experience by taking another 20 mg 2C-C but it also lasted only for about an hour, not really adding anything but a few breezes of psychedelia.

I got frustrated, almost angry, and just wanted to go to sleep. I decided to knock myself out with 150 mg quetiapine (Seroquel), 30 mg propranolol (for the quite high hart rate) and 3 mg melatonin. I slept for maybe 4-5 hours. I don't have any after effects today.

What on earth happened? I'm sure you'll ask if I use MXE often and have a high tolerance and yes, I use MXE frequently but usually not over 100 mg and hadn't used any for over a week. The batch is good, it was good just a week ago. I felt cold and empty inside, had no insight, was just very confused (couldn't type with my keyboard) and frustrated. This has never happened before. My last 120 mg experience with the same batch was a blissful, euphoric and insightful trip...But it's rarely I use such high doses.
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Dude you gotta close your eyes! Put on a candle. And don't move at all! My last two trips like this sent me faaaaar away into magical land.
The first few times I tried it I felt 'empty/stupid/confused/dizzy' and didn't get anything out of it even when I upped the dose considerably.
 
Scunch said:
If you begin to feel antsy or the nature of reality starts to bother you either get up and dance/stretch or close your eyes. Make sure to stay warm, all my worst trips have been when I was cold, it made me feel empty.

Fuck, I might dose a couple of times before bed, this stuff is too great.

How do you guys spend your trips?
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Yes staying warm is a very good point! Otherwise I start shivering and shaking and it's very uncomfortable! Good advice.
 
Jinux said:
It's not too trippy in general, K is a nice drug. It's just too trippy for this situation. I don't want to be out of my mind, just chilled, happy and calm.
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i would recomend baclofen(10-50mg) for when you have to do unpleasent tasks. it lowers my irritation significantly while it keeps my thinking intact it also works great for my weed cravings.
 
Reverberation, there's a long post I originally typed up many months ago and eventually got round to posting here. It doesn't capture everything, but kinda manages to convey some of the many impressions I had of my first M-hole.
 
-snip-

You're new and I understand you're clearly just joking around, but joking about snorting a gram of a very potent and unresearched chemical is not cool. Someone could take it the wrong way and get seriously hurt or worse. ~Jesusgreen
 
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Reverberation, there's a long post I originally typed up many months ago and eventually got round to posting here. It doesn't capture everything, but kinda manages to convey some of the many impressions I had of my first M-hole.
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Thanks for the link, really can relate to the sensation of being lava! Tripping, not tripping, wait was I? What the?....


I'm always in bed while holing and it seems my bed with me in it gets flown around all kind of sights. The feeling of moving can become very real and intense but at the same time it can be over very fast, you just turn your head and your back in your room. Its quite beautiful to get swept away in, always has a color pattern and general theme of some sorts... plus it feels completely safe, there is no anxiety whatsoever...
 
Jinux said:
Well what would you suggest for the dose with the least impairment while still keeping me calm?

I understand that I'm going to feel different, I'm not expecting to suddenly just not be agitated :P
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if you were to try to take k as an anti depressant it would be in dosages below what you would take to get high.

Ketamine works miracles as anti depressant. Read the link I posted and the op specifically mentions taking ketamine at low doses so as to not get high. Also research the subject and you'll find TONS of medical literature on it.

MXE is reported by alot of people on Bluelight (not nearly as good as having actual clinical studies I know) to be an anti depressant also. And it makes sense given its similarities to ketamine.

I really recommend at least researching K as an anti depressant and not something to get you high. And from there extrapolate to MXE. (very unscientific btw)

I find it worth noting though that taking MXE and not getting high could be rather hard given that its active in dosages as low as 5 mg according to some. (id say more around 15-20 mg but evryone is different). I suppose it does have the advantage of being semi legal though...

If you don't mind me asking, why would you pick an RC over something that's already been clinically tested for an anti depressant?
 
I'll ask Jinux to post back here but MXE does have the advantage of being more potent - and so as a direct result much cheaper for this purpose, and it also has a stimulating effect, and he has found light stimulation to help him with the agitation etc. It's also less impairing at a lower dose in my experience than Ketamine is - on Ketamine even the smallest doses left me feeling quite off, talking a little weirdly, and with some trouble walking.

Plus there's that rather large advantage of not having to deal with the black market, particularly since he hasn't bought anything illegal in > 2 years, so it wouldn't necessarily be the best option to go down that route, no?

AFAIK he already has some MXE on the way so he's just looking for the best way to approach his use for his particular issue. By the looks of it 5mg would be a good starting point, and I may attempt that dose today to add my own opinion :)
 
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If you don't mind me asking, why would you pick an RC over something that's already been clinically tested for an anti depressant?
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Not OP but classic antidepressants often lower libido to zero, take time to work, sometimes not work at all and, reported often by my uncle who used many, make you slime.

It takes long, long time before you can find that one antidepressant which CAN work for you.

Dissociatives not only work immidietaly, but also can be mixed with other things (to some degree).

Considering clinical tests, are you talking about general tests (MXE isn't really tested for anything, right?) or those which test a substance for antidepressive qualities? If the latter, why care? Many people used it this way, and you can try it yourself.

Haven't heard of it being counter-antidepressant.
 
Oh, sorry. Fail english. I mean being sleepy, talking slurry etc. not being yourself and very "active" thinking.

Did you really survive abortion?
 
Jesusgreen said:
I'll ask Jinux to post back here but MXE does have the advantage of being more potent - and so as a direct result much cheaper for this purpose, and it also has a stimulating effect, and he has found light stimulation to help him with the agitation etc. It's also less impairing at a lower dose in my experience than Ketamine is - on Ketamine even the smallest doses left me feeling quite off, talking a little weirdly, and with some trouble walking.

Plus there's that rather large advantage of not having to deal with the black market, particularly since he hasn't bought anything illegal in > 2 years, so it wouldn't necessarily be the best option to go down that route, no?

AFAIK he already has some MXE on the way so he's just looking for the best way to approach his use for his particular issue. By the looks of it 5mg would be a good starting point, and I may attempt that dose today to add my own opinion :)
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Not wanting to deal with the black market is rather smart. I however think ketamine presents some advantages over mxe in the ops situation as far as its use as anti depressant. MXE is stronger at loewr doses that while present the advantage of making more cost effective its also would make you trip harder from less. which isnt that great if your looking to be at work and aren't exactly experienced in these manners.

I guess if he already has it coming than theres no point in even mentioning it though.

op should definatly be careful to not develop an psychological dependance on teh stuffzz though. Both mxe and K can definatly be rather habit forming. Erowid recommends for Ket (and obviously mxe) to set your self a limit not to go over BEFORE you take the drug. This way you dont go crazy on it. Which, believe it or not can happen with a bit of tolerance.
limitbreaker said:
Not OP but classic antidepressants often lower libido to zero, take time to work, sometimes not work at all and, reported often by my uncle who used many, make you slime.
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I was talking about ketamine which in all fairness can make do all the same things to you if used irresponsibly lol
 
Truth there... so hard to stay out of it when you have a bunch sitting around... I finally had to just not order any more... on the bright side tho I didn't experience any issues like withdrawal symptoms or depression or anything when I finally did quit a month ago... I'm going to order a litttle more tomorrow but only 3 grams and 2 is for someone else... I'm curious to see how much my tolerance has dropped... I used to average a half gram a day since early june... and was pretty much burnt out on it... got no euphoria or psychedelic effects anymore just this distant dissociation from life and lingering stimulation and insomnia...
 
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