I had my first negative experience with MXE yesterdy.
First I took 50 mg 2C-C which was a huge disappointment. The come up was as usual, but the actual trip lasted only for about an hour and suddenly dropped very rapidly (I've used the same batch not too long ago, and my trips are usually 4 hours). Then I decided to continue the evening with MXE. First I took 40 mg. This felt good, but not that strong. I continuted with two redoses, 35 mg and 40 mg so altogether 115 mg MXE. The result was a strong confusion and disorientation, but absolutely no euphoria, no joy, nothing enjoyable. I felt cold and empty inside. Almost like I had no feelings at all. It's a good batch, I usually use it in the 60-80 mg range and have had great trips. I tried to boost the experience by taking another 20 mg 2C-C but it also lasted only for about an hour, not really adding anything but a few breezes of psychedelia.
I got frustrated, almost angry, and just wanted to go to sleep. I decided to knock myself out with 150 mg quetiapine (Seroquel), 30 mg propranolol (for the quite high hart rate) and 3 mg melatonin. I slept for maybe 4-5 hours. I don't have any after effects today.
What on earth happened? I'm sure you'll ask if I use MXE often and have a high tolerance and yes, I use MXE frequently but usually not over 100 mg and hadn't used any for over a week. The batch is good, it was good just a week ago. I felt cold and empty inside, had no insight, was just very confused (couldn't type with my keyboard) and frustrated. This has never happened before. My last 120 mg experience with the same batch was a blissful, euphoric and insightful trip...But it's rarely I use such high doses.