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The Big & Dandy Methoxetamine Thread - 5th Dose (you took too much, seriously)

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Chemically Insane said:
@ ozchems- yes very similar to a k hole... the main difference is that k is much more incapacitating physically...when your at that level your stuck flat on your back... but mxe is more like pcp in that you can be deep in the hole and still be walking and taking and such... but the trip itself feels much more like k to me only warmer and friendlier and more tactile....
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most definitely which sucks ass because ill catch myself "duck walking" around the house and communicating with people that definitely do not need to know that i am that fucked up. i truly enjoy ketamine much more, it keeps me in my place and even if i try to get up out of bed i usually fall back into bed.

edit: @ chemically insane, i have only I.M.d mxe.. sorry cant help you on comparing other ROA.
2nd edit: since MXE supposedly hits your mu // opiod receptors i have found it to help me out while dopesick.. not just while on it either but not exactly an afterglow but i didnt feel sick for a few hours afterwards.
3rd edit: i wouldn't exactly call I.M. dosing shooting up but yeah i think we all get the point.
 
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Chemically Insane said:
It was truly a very special experience there were definately some scary and some very emotional parts but It wasn't really like a bad trip it was more like something you didn't understand or couldn't comprehend that was alarming but at the same time... as the trip progressed these same things became understandable and were no longer scary... in fact thet now made sense and you then wonder why everyone else is so scared of them...

At one point I was in a very bright place... I was moving at tremendous speed but couldn't see where I was going because every direction looked like looking into a spotlight.... I was pretty certain that I was dead and this was the light you see.... but once your "eyes adjusted" I could see that I was in a very special place... a place of the gods.... and I'm an atheist... but it was a special place once you understood it....
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I get you too :)
 
^
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There have been numerous times during my combinations of MXE, DXM, and ondansetron (I have no health issues combining MXE and DXM) where I have seen a bright light. It almost seems to be shining out from the back of my eye balls. I'm always looking behind me expecting to see the glow of the computer monitor or my phone, or any luminous thing. I also have a lot of experience with "adjusting" my eyes to see new dissociative vistas. I do this by shifting my attentional focus to points outside my optical focus. Opening my eyes when they're extremely close to the surface of a pillow is another way I've found I can bring out MXE's unique open eye visuals. Granted, I'm not sure if you meant to allude to the status of the eyes when you say "eyes adjusted" or if you're just using a simple metaphor.
 
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is it a fact that it affects opiate receptors, or is that just speculation?

i mean, ive got some anti nausea pills called zofran that work wonders for being dopesick, but thy arent in any way related to opiates...just curious really..
 
bluedolphin said:
To lower tolerance:

take a few days off MXE, and during these days take some pretty heavy doses of Piracetam.

Maybe a week of this if you've got a pretty serious tolerance.

worked for me, more than once ... now I always rage Piracetam in between MXE stashes ;)


give it a shot, I'd like to hear if it works for others as well
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Can you be a bit more specific on the dosage of piracetam?

cheers
 
Weird that sometimes, MxE gives me what feels like an amphetamine/cathinone type rush feeling. I had a key (25mgish) about 20 minutes ago and I feel rushy as...
 
plusfourpirate said:
is it a fact that it affects opiate receptors, or is that just speculation?

i mean, ive got some anti nausea pills called zofran that work wonders for being dopesick, but thy arent in any way related to opiates...just curious really..
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I believe that's theory based on structure activity relationship. However, if I recall correctly someone formally tested 3-MeO-PCP's mu receptor binding ability and found it did not bind at all (the post may be in the B&D 3-MeO-PCP thread). It's still up in the air as to whether methoxetamine (3-MeO-2-Oxo-PCE) affects opiate receptors as far as I know. It doesn't feel like it to me, but then again I thought 3-MeO-PCP DID feel opiate like in some ways. I can say, though, that methoxetamine potentiates opiates for me.
 
I haven't done any real checking on it but in the wikipedia entry for ketamine is mentions something about binding without agonist activity to mu opioid receptors...

http://en.m.wikipedia.org/wiki/Ketamine

But aside from that... I've given mxe to someone going thru withdrawals and they said it helped immensely...

plusfourpirate said:
is it a fact that it affects opiate receptors, or is that just speculation?

i mean, ive got some anti nausea pills called zofran that work wonders for being dopesick, but thy arent in any way related to opiates...just curious really..
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^Re: ketamine -- that's at "high, fully anesthetic-level doses". DXM has also been helpful for opiate withdrawals according to reports, despite being negligibly active at mu receptors (to my knowledge). The pharmacology of many dissociatives and opiates clearly interacts, though, and so I do not discount the value of disassociatives for those looking for relief from opiate withdrawals. I don't imagine it will be too much longer before someone reports something definitive about methoxetamine's potential opioid receptor activity (if it's not out there already).
 
Chemically Insane said:
@oykef- Have you used mxe before? If so, what doses? How often do you use Tramadol? What is your Tramadol dosing regimen? Do you take anything else?
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yes i had an insane time with mxe before for a few months dosing up to 2 grams in 2 day sessions.

been off it for a while but when i do do it now i limit myself to tiny bumps not 300mg lines, 100mg in a night tops now.

also when i was younger did up 900mg tramadol in a day but havent done it for years apart from a few times in the last week.

will add i didnt learn about the 400mg ceiling for tram until about a year later, boy was i shocked.
 
You seem pretty experienced... lol... I've never been into tramadol and when I was into opiates I wasn't into dissociatives... so eh...

If you were a noob id say its probably best to wait till tomorrow before mixing stuff like painkillers and anaesthetics... but it sounds to me like your more of a experienced experimenter so my advice is to just start low... you seem to be able to handle whopping mxe doses... I don't specifically know of any interactions between ketamine and similar drugs to tramadol... but if I were you I would google something like "ketamine tramadol interactions" and see what comes up before taking the mxe... mxe is basicly the same as K or PCP pharmacologically....
 
What do you guys reckon about doing MDMA the day after (low amounts of) MXE? I was planning to go to the museum on a little bit tomorrow then go partying on friday, but wanted input on that since I'm very catious
 
I take mdma and mxe in combination at fairly high doses and haven't had any adverse effects.... I actually think mdma and mxe go together perfectly... just make sure your mdma isn't adulturated.... I'm speaking specificly about mdma.... adulturants are a whole different issue...
 
Well if they go together okay then hopefully there'll be no problem doing MDMA tomorrow night. I'm about to dose and go to the science museum, woo
 
Guys. Question: Is it normal that I have never actually had any hallucinations from this drug before (or Ketamine for that matter)? Whilst I feel separated from my body and mind at high doses, I never actually "trip" or "hallucinate" if that makes sense. With MxE, all I get at doses of 15-50mg is intense euphoria and a slight drunken feeling. Don't get me wrong, I love it but I don't understand why I never experience any of these hallucinations that everyone bangs on about... Even when I did 150mg nasally all at once, I never actually hallucinated.

My current state is a prime example. I took 50mg nasally about 30 mins ago. I have extreme euphoria and colours look incredibly inviting. I feel all fluffly and lovely (makes me wonder if it acts on serotonin at all as I often feel empathic on Methoxetamine<3) but everything looks completely normal to be honest. I'm not tripping or hallucinating though I've seen 50mg send friends to another planet. :D

I'm having the time of my life, don't get me wrong. But I don't understand why I've never hallucinated before on arylcyclohexylamines...
 
Xamkou said:
Guys. Question: Is it normal that I have never actually had any hallucinations from this drug before (or Ketamine for that matter)? Whilst I feel separated from my body and mind at high doses, I never actually "trip" or "hallucinate" if that makes sense. With MxE, all I get at doses of 15-50mg is intense euphoria and a slight drunken feeling. Don't get me wrong, I love it but I don't understand why I never experience any of these hallucinations that everyone bangs on about... Even when I did 150mg nasally all at once, I never actually hallucinated.

My current state is a prime example. I took 50mg nasally about 30 mins ago. I have extreme euphoria and colours look incredibly inviting. I feel all fluffly and lovely (makes me wonder if it acts on serotonin at all as I often feel empathic on Methoxetamine<3) but everything looks completely normal to be honest. I'm not tripping or hallucinating though I've seen 50mg send friends to another planet. :D

I'm having the time of my life, don't get me wrong. But I don't understand why I've never hallucinated before on arylcyclohexylamines...
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I lost most of the visual effect from mxe after a few holes, but after i tried plugging it they came back with a vengeance...

Try 50mg oral +50mg plugged and then tell me it wasnt visual=D
 
I've found tolerance builds pretty quick with this stuff... especially the hallucinogenic effects... after a week and a half of abstinence I found that the anaesthetic effects return much more strongly than the visual side of it...

But after the first cople deep holes I didn't get much visually either anyway with eyes open anyhow... eyes closed its a whole different story... especially with some dirty sexy house music...

This kinda stuff is my fav on mxe/k....

http://notownbeats.com/music/miss-cooper-distrikt-live-reno-2011.mp3
 
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