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Dissociatives The Big & Dandy DMXE (3-me-2′-oxo-PCE, deoxymethoxetamine) Thread

think this stuff needs a wash i got the slightly yellow off white powder that others have reported and i get headaches and sweaty from 40+mg im its effects are very dark and relentless compared to ketamine feel more dizzy and disoriented so i think the impurities are making it less enjoyable ymmv
Did you ever wash any?
This chemical has very ethereal trail by fire type experiences using IM, was pretty awesome lol. I just ordered 2 more grams.
Feels like it's not good on your heart, Ive heard the same about mxe so be careful with how high you dose.
Can you elaborate on the heart comment? Did it burn for you when IMing?
Guess what I got sold…
A mixture of pcp derivates, 3:
-3,4 dimethylphenyl
-2,6 dimethylphenyl
-2,5 dimethylphenyl

And I was wondering why my 3me-pcp was that icky when dosed higher…
😳🤔
Hello you all, so those days i wanted to go back trying DMXE, MXiPr and MXPr, but i don't want to snort anymore because since ~2 months snorting is almost always resulting in inflamed nose for few days to a whole week, which is pretty uncomfortable and ugly.
I wanted to try to do nasal spray solution, but i saw that i should acetone wash my drugs prior as possible impurities will ruin the dissolution, it is a bit much of preparation (and expansive, have to buy good spray bottles, find anhydrous acetone, etc), in comparison to what i was able to do only by putting a line in my nose.

Is there ways to make snorting less irritating ? By putting the powder in saline water and snorting the water+powder ? Or doing this with a nose syringe ?
I could stick to oral but after all what i read of them being less effective orally than nasally i wonder if it's worth it, i have little to no tolerance (i often do months breaks and only use sparkly in 1-2 week when i receive a disso).
Or can i vape it in putting it in my e-cigaret vape ? Is there instructions to follow in this case and is it an interesting ROA ?

Thanks
Did you ever wash any?
 
Hi all.
New here, but just wanted to give my opinion on DMXE.
MXE was to me absolute bliss. I loved it from day one of release, and it was a sad day when it disappered from the scene. So I was really curious and intrigued when I saw DMXE was released, and of course I had to try it. I'm not disappointed, of all new dissos this one (IMO) resembles MXE the most, but something is definately lost when that oxygen is removed. It's as if the magic MXE possesed is gone or at least dimished. It doesn't have the same antidepressant effects that MXE did, and the afterglow to me is quite dysphoric and a little irritating compared to MXE, I loved the afterglow of it. Compared to K or DCK it certainly has a manic edge to it on par with MXE.
As a MXE lover, DMXE it certainly worth a try, but I probably won't sample it again. Doses were ranging from 20 to 70 mg. ROA was IV/IM. IV sucks compared to MXE, ket or DCK as it takes quite some time to build up to full effects, perhaps 2-3 min or so.
If you never had MXE and wish to have an experience that resembles, give it a try, but this is not MXE, and personally I'd prefer ket or DCK. I have always loved mixing dissos and psychedelics, and perhaps adding a 4 sub tryptamine would add an interesting dimension and perhaps even a touch of magic to the DMXE experience, but I have yet to try.
MXE always f***ed with my ability to pee, DMXE does just the same. Spend two painful hours by the toilet zink, splashing cold water on my pee pee and lower stomach, just to get restored the connection, so empty your bladder before use, not being able to pee for a long time is painful and potentially dangerous.
 
Was MXE really that bloody good? If ketamine is a 5/10 on a scale from 1/10, how good was MXE and did it have an iv rush?
MXE was a dream to IV. Instant bliss. DMXE IV sucks compared to. It takes 2-3 minuttes for full effects to manifest.
 
Interesting, I get that difficulty peeing effect from serotonergic stimulants very strongly, but never got it from MXE.

I agree about DMXE, it is missing something very distinctly compared to MXE, but it is similar in many ways. It has a lot of the wonkiness, but the warm magic of that wonkiness is missing.
 
If K is 5 out of 10, I would personally rate MXE as 9. Considering I find it to be perfect, and my favorite dissociative by a mile. But in reality on the disso scale I would rate ketamine a 6 or 7, and MXE a 10.
 
Ket is still my favorite because of how long most analogues stick around in the body.
I still remember smoking weed the day after mxe could really bring back alot effects.
 
yeah that's a definite positive to ketamine, not only does it wear off quickly and without a residual tail end, it is not stimulating and you can easily fade into sleep directly from a hole, and in any case it won't keep you up half the night afterwards. If ketamine had the magic of MXE I would probably rate it tied with MXE anyway, but MXE just has the most profound sense of magic and wonder to it, and the perfect blend of functional and deep/wonky, so it has to win by a longshot.
 
If K is 5 out of 10, I would personally rate MXE as 9. Considering I find it to be perfect, and my favorite dissociative by a mile. But in reality on the disso scale I would rate ketamine a 6 or 7, and MXE a 10.
Where would you rate DMXE?
 
Uhh... probably about equal with ketamine I guess. Ketamine has never quite done it for me, unlike for some. I like it, but there are various ones I like better. For example, I would rate 3-MeO-PCE as an 8, just below MXE. Also 3-HO-PCP an 8.
 
Uhh... probably about equal with ketamine I guess. Ketamine has never quite done it for me, unlike for some. I like it, but there are various ones I like better. For example, I would rate 3-MeO-PCE as an 8, just below MXE. Also 3-HO-PCP an 8.
Ketamine doesn’t really do it for me either. I’ve only done it a few times. Just got a sample of DMXE the other week and once I get the lab results back I’ll be taking it for a test drive.
 
I found the anti depressant and pain management properties of dmxe to be exactly the same as mxe.
When comparing apples to apples as in no other drugs used for a while when having used them.

My first dmxe 'trip' headed exactly the same way as loads of mxe trips. The dmxe just stops short of the full journey as in no dissociative effects.

I only had one trip like that with dmxe and I was desperate to hole so took about 500mg+ and ended up being stiff for over 20 hours.
I didn't stop grinning that whole week.

The other times I took less of the dmxe like 120mg and they were ok nothing special trips. Still antidepressant and pain management effects present for about a week.
Then to avoid tolerance of once weekly usage I switch to other stuff to alternate.

I should get some ketamine and some 3-meo-pce.
Not had ket for over two decades.
 
Can't remember if I've commented in this thread yet, haven't been around for awhile so possibly not, or I have but forgotten, but I've had the good fortune to try DMXE a few times in that time.

For me, this is actually a superior substance to MXE Itself - for one, while I always found MXE to be quite hard to actually "hole" on in the same way as ketamine is, this substance actually has a hole which is comparable, but also different, somehow more exotic, colourful, less "dark" feeling than ketamine (I don't mean dark as in, bad, I mean literally, dark, most of my holes on ketamine are journeys through somewhat dimly lit spaces - this substance in contrast seems to offer journeys through more brightly lit spaces).

Additionally, in low doses I find it to be far more reliably euphoric and stimulating - I know many dissociatives act like stimulants in lower doses to some degree, but this substance seems to have some significant dopaminergic action (or at least, just "happy action", who knows - at least, I don't know, really - exactly what neurotransmitters are involved to what degree).

The only thing I dislike about this substance is that it seems to give me a kind of verbal stutter and awkwardness in trying to talk or even communicate nonverbally (by which I mean like, texting, not body language and whatnot) at a dose which is too close to the threshold stimulant-esque dose but still too far from the Hole, complete-immersion level of dose. I get this on ketamine too, sometimes, but the line at which I begin to have difficulty communicating is far closer to the actual Hole, so, IMO, less of an issue.

If I had to rank dissociatives out of 10, for reference, I'd put ketamine at a 9, MXE probably a 6, and this would be an 8. Although I think actually all 3 substances are different enough that this scale is kind of apples and oranges and really it depends what you're looking for in a dissociative. As someone who is a fan of Hole doses, the fact that this substance has a pretty deep Hole that is not just bafflingly alien and actually kind of dysphoric as I always (well, almost always) found MXE holes to be significantly boosts it's score. If Holing isn't so much your bag but you prefer to remain somewhat associated with the physical world - well, actually, this substance is pretty damn good for that too, IMO. It's a pretty solid all rounder, actually more euphoric even than ketamine, I'd say, but the verbal impairment and probably other impairments I haven't noticed (I don't really move around too much on dissos) would be a negative.

Actually I had one experience on this substance which was pretty concerning. I was staying at a house that was not mine, at some point I must have gone to the bathroom, because I had been doing DMXE in the room I was staying in but then woke up, slowly realising I was lying face down on the bathroom floor (it was carpeted, eurgh) while thinking I had made it back to the room I was staying in and was in bed.

I don't know how long I was there for, I really don't know at all what happened. It's not the first time I've misjudged a hole but the fact I was actually face down on the ground as if I'd passed out (although i had no obvious signs of injury - I could still have just fallen kind of fortuitously) or at least, with some kind of complete memory gap was pretty worrying. That only happened the one time however.
 
Wow, you're the first person I've heard say this is superior to MXE. For me, MXE is great for holing but also fantastic for any other dosage level. In contrast to your experience, I have found DMXE to feel "colder" than MXE, or ketamine. And I find MXE "warmer" than ketamine.

I am always fascinated by how much variance between individuals there is with dissociatives.
 
I can understand, I think why some people (most people, apparently) find MXE to be "warmer" than ketamine, and I can identify aspects of it that are - I think ketamine's sense of depth is somewhat illusory, but it is a very convincing illusion. MXE on the other hand feels somewhat less illusory, but for me it's depth is not something I really understand how to navigate. Ketamine can indeed feel quite cold, but speaking for myself, this coldness is a veil which masks an inner warmth and sense of connectedness to some fundamental layer of reality. There is coldness on both sides however, ie, approaching the warmth and leaving it, and this taints the experience but for me the memory of the layer of warmth outweighs the veil of "coldness" that surrounds the experience. MXE on the other hand I find to be a maze. I've had truly transcendent experiences with MXE that eclipse anything I've experienced on ketamine - however usually in combination with other drugs that somehow clear the path through the maze of dysphoria to the warmth at the core of the experience. But, for me, most of the time it's just very hard to find.

I'm not sure if that makes much sense at all but, it's really the only way I can think to describe it. DMXE on the other hand is not a maze, to me. The "journey" through the experience is more linear, akin to ketamine, but the character of the experience has the inner warmth of MXE which I have touched but usually find very difficult to find.

Again - not sure how much sense that makes but, it's the best I can do to describe the nuances I perceive these substances to have and how they relate to each other, while retaining their own unique character as well.
 
MXE on the other hand feels somewhat less illusory, but for me it's depth is not something I really understand how to navigate.
MXE was the same way for me. I would always aim my doses right below a holing dose, and try to straddle the line. When I did overshoot it I would always end up very confused, merging with objects in the room or scenes on TV, blacking out, etc. K is much more clear-headed and structured at hole doses in comparison.

The problem with K is that low doses aren't enjoyable for me, and I enjoy holing a lot less than I used to. I miss the low-medium doses of MXE they felt so magical and gave the world so much sparkle.
 
Hi all.
New here, but just wanted to give my opinion on DMXE.
MXE was to me absolute bliss. I loved it from day one of release, and it was a sad day when it disappered from the scene. So I was really curious and intrigued when I saw DMXE was released, and of course I had to try it. I'm not disappointed, of all new dissos this one (IMO) resembles MXE the most, but something is definately lost when that oxygen is removed. It's as if the magic MXE possesed is gone or at least dimished. It doesn't have the same antidepressant effects that MXE did, and the afterglow to me is quite dysphoric and a little irritating compared to MXE, I loved the afterglow of it. Compared to K or DCK it certainly has a manic edge to it on par with MXE.
As a MXE lover, DMXE it certainly worth a try, but I probably won't sample it again. Doses were ranging from 20 to 70 mg. ROA was IV/IM. IV sucks compared to MXE, ket or DCK as it takes quite some time to build up to full effects, perhaps 2-3 min or so.
If you never had MXE and wish to have an experience that resembles, give it a try, but this is not MXE, and personally I'd prefer ket or DCK. I have always loved mixing dissos and psychedelics, and perhaps adding a 4 sub tryptamine would add an interesting dimension and perhaps even a touch of magic to the DMXE experience, but I have yet to try.
MXE always f***ed with my ability to pee, DMXE does just the same. Spend two painful hours by the toilet zink, splashing cold water on my pee pee and lower stomach, just to get restored the connection, so empty your bladder before use, not being able to pee for a long time is painful and potentially dangerous.
Try good amounts of green tea before and after taking the dissos. It will probably easy all the pee symptoms and keep the bladder safe.

For me was a total gamechanger
 
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