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Tryptamines The Big & Dandy 5-MeO-MiPT Thread - Part 2

I get the weird energy and sharp vision at the low dose as well, I just can never seem to find an outlet for it. I end up sitting around zoning out on TV and video games.

I did take a low dose while hiking once and it worked well for that. The energy boost was welcomed as it kicked in during a long up hill portion on the hike. I still felt mentally stoned though even before mixing in cannabis later on down the trail. I do prefer it over a classic stim. It feels like a background substance at the lower end.
 
Yes, all psychedelics and in fact all serotonin agonists/releasers are cross-tolerance with one another. Tryptamines are most cross-tolerant with tryptamines, phenethylamines with phenethylamines, ergoloids with ergoloids, but they also all produce cross-tolerance across groups.
 
I've noticed something with this compound since I've been using it. I've had cluster headaches for many years since a concussion in my teens. I've been on a lot of things for them over the years but I never really found anything that worked with tolerable side effects.

I'd read about psilocybin begin effective for migraines so I got curious. Sadly I didn't have access to any shrooms to test if they would work for me so I turned to this compound.

Anyway a couple of months ago I started having episodes of cluster headaches which usually take days to clear up on their own. When the pain levels had set in pretty well I dosed 10mg of 5-meo-mipt. Within 45 minutes of ingestion the pain started to ease off, by the 2 hour mark it was gone all together. Headaches didn't return for another month.

Since that first attempt I've found I don't need such a high dose. If I feel headaches coming on I can ingest 3mg or so of 5-meo-mipt and avoid them all together. If I wait for them to set in completely that same dose is effective for aborting the headaches completely within 1-2 hours. For me this stuff is quickly becoming a life saver.

If anyone out there is doing research on using tryptamines for treatment of migraines I urge them to give this one a look. I think it would be a good candidate for begin used as medication since a low dose doesn't really keep me from going about my day while killing the pain completely.
 
HeadphonesandLSD said:
I've noticed something with this compound since I've been using it. I've had cluster headaches for many years since a concussion in my teens. I've been on a lot of things for them over the years but I never really found anything that worked with tolerable side effects.

I'd read about psilocybin begin effective for migraines so I got curious. Sadly I didn't have access to any shrooms to test if they would work for me so I turned to this compound.

Anyway a couple of months ago I started having episodes of cluster headaches which usually take days to clear up on their own. When the pain levels had set in pretty well I dosed 10mg of 5-meo-mipt. Within 45 minutes of ingestion the pain started to ease off, by the 2 hour mark it was gone all together. Headaches didn't return for another month.

Since that first attempt I've found I don't need such a high dose. If I feel headaches coming on I can ingest 3mg or so of 5-meo-mipt and avoid them all together. If I wait for them to set in completely that same dose is effective for aborting the headaches completely within 1-2 hours. For me this stuff is quickly becoming a life saver.

If anyone out there is doing research on using tryptamines for treatment of migraines I urge them to give this one a look. I think it would be a good candidate for begin used as medication since a low dose doesn't really keep me from going about my day while killing the pain completely.
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This is fascinating! How sad that research on the medical uses of these compounds has been suppressed for so long.
 
Hey all, I've been experimenting with this substance for a little while and have a question. A side effect I get from it is uncomfortable muscle tension, which seems to happen any time I go above 3.5-4 mg - I've never taken more than 5 for that reason. I want to experiment with higher doses because I really like the positive effects, but the muscle tension is a serious buzzkill. If anyone else gets this, does the muscle tension increase linearly with the dose or is there a threshold, kind of like how the dysphoric aspects of shrooms get overpowered by the euphoria when you find the right dose? Basically I'm trying to figure out if I'm taking too little or I'm just extra-sensitive to this substance.
 
Mushrooms can never be totally reliable unless you get it industrialized, like we had in Amsterdam.
 
me and my friend did 5 mg oral last week.

very mils but very smooth. full of light, very smooth experience and overall quite potent even at 5mg.

will try 10mg soon!
 
buttannibal69 said:
Hey all, I've been experimenting with this substance for a little while and have a question. A side effect I get from it is uncomfortable muscle tension, which seems to happen any time I go above 3.5-4 mg - I've never taken more than 5 for that reason. I want to experiment with higher doses because I really like the positive effects, but the muscle tension is a serious buzzkill. If anyone else gets this, does the muscle tension increase linearly with the dose or is there a threshold, kind of like how the dysphoric aspects of shrooms get overpowered by the euphoria when you find the right dose? Basically I'm trying to figure out if I'm taking too little or I'm just extra-sensitive to this substance.
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Do you get muscle tension from other psychs? It's definitely the most common side effect I experience. I haven't tried this yet but I have some on the way so I'll post when I've tried it.
 
Doldrugs said:
Do you get muscle tension from other psychs? It's definitely the most common side effect I experience. I haven't tried this yet but I have some on the way so I'll post when I've tried it.
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me too. I got the muscle tension with 5mg. it wasnt too bad, but I felt a bit of that.

I think its safe until you go to like 40mg or so, which I will never try. IM sure 20 mg is enough for a strong experience?

I would also like to know if the muscle tension increase a lot the higher you dose?
 
I've tried a number of psychs but 5-meo-mipt is the only one so far that's given me truly uncomfortable muscle tension. Magnesium helps, but my question is whether the muscle tension just keeps getting worse and worse the higher you dose or if it plateaus at any point.
 
It gets worse... But honestly it's the vasoconstriction that bothers me more than the muscle tension at higher doses. Mostly just it freaks me out and makes me start dwelling on it.

I've taken doses as high as 20-30mg and come out ok--though with lingering vasocontriction for days afterwards. Generally wouldn't recommend people push it with this chemical. Stick to 7-10mg. Or 2-5mg to keep negative side effects down.

In short: yes, it gets worse.

Edit: I've used ginkgo biloba and l arginine to some success. Also staying active really helps. This is definitely not a chemical to sit around on. Take a walk.
 
thanks, InterestingFACT! yeah i noticed the last time i tried it that being in a party environment with lots of moving around eased the negative side effects. when i'm in a lower-key environment the initial nausea always makes me want to sit down, but at the party i didn't even notice it. having a little food in the belly also seems to help.
 
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