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The Big & Dandy 4-AcO-DMT Thread - Act Four

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I always choose insufflation for the shorter duration as I usually dose somewhat late at night. Is the oral bioavailability that much higher?

EDIT: I would also like to add that my doses aren't usually that high. 20mgs puts me in a nice place and 30mgs will have me tripping hard. The only time I dose that high is when mixing it with mxe as it eliminates all of the anxiety I usually experience when coming up on tryptamines.
 
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Oh ROXIanne! said:
I always choose insufflation for the shorter duration as I usually dose somewhat late at night. Is the oral bioavailability that much higher?

EDIT: I would also like to add that my doses aren't usually that high. 20mgs puts me in a nice place and 30mgs will have me tripping hard. The only time I dose that high is when mixing it with mxe as it eliminates all of the anxiety I usually experience when coming up on tryptamines.
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I'm pretty sure it is, snorting it felt real weak to me compared to orally. As did smoking and plugging.
 
Oh ROXIanne! said:
^4-5 hours IME
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applies to my reactions with that lovely Psilacetin!

snorting is something i'm not yet sure about.- but it really doesn't seem to be the best "ROA" .

"The real cause" (Wtf?!?-right _now on_ da ACO) of my post is a BIG thank to all you lovely bluelighters with +/- infos on dat ACO immensly helped not only me and my loved ones but .. well.. helped .. the world to become a better place <3

Right now me and my lady came down from (_no typo_) 65-80 mg. each! , spaced over 3-4 hours. so amazingly great, healing, words to descripe would just be a waste- (coming up strong on another 19-26mg each. , right now)

love yall on here

P.S.

My lady took her methadone substitute(70mg) right when coming up first- she ~had~ to.
before both of us took 2mg clonazepam(might have clouded things too much8)

before and during the "trip" I repeatedly consumed street amphetamine. which was -and still is - a mostly good combo for me.;)
gotta take care of my lady and me now-flying _high_) By

<3
By
 
Thinking of ingesting approx. 40 mg.... I took a dose of approximately 30 mg and definitely felt like I could have taken it further. What do y'all think of a dose that large?
 
I really liked when I did 4-aco-dmt.
I only dosed intranasally though from the lack of an accurate enough scale.
I didn't think it was exactly like shrooms but I think this is because I only snorted it.
Is it true it is metabolized differently orally?
 
.:Holy::Toast:. said:
I really liked when I did 4-aco-dmt.
I only dosed intranasally though from the lack of an accurate enough scale.
I didn't think it was exactly like shrooms but I think this is because I only snorted it.
Is it true it is metabolized differently orally?
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Of course it will be also I think orally is better and stronger.
 
Greetings! I have acquired some 4-aco DMT and 4-ho-MiPT, and have ingested both today. I took 14 mg. of mipt in a gelcap and felt no effects, then insuffulated 10 mg. of aco - DMT and felt no effects. I take a number of psychiatric medications, which I suppose may be blocking the effects? I'm very confused at this point and measured out 33 mg. of 4-aco-DMT and put it into water which I am now drinking. The medications I take are Neurontin, Celexa, Trilafon, and Remeron. I feel confident that the source is not the likely issue, though I may be wrong. What am I doing incorrectly? Halp! :/
 
BlobSnail said:
Greetings! I have acquired some 4-aco DMT and 4-ho-MiPT, and have ingested both today. ... The medications I take are Neurontin, Celexa, Trilafon, and Remeron.
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Holy crap. I hate to ask the obvious question, but ... if you need that much medication to function normally, should you be doing psychedelic drugs?

Assuming you think that you should, it's probably the celexa. SSRIs block the action of serotonergic psychedelics. For example, last year one of my friends on an SSRI took a couple tabs of acid that had floored me, and he didn't feel a thing. I wouldn't recommend discontinuing your medication so that you can get high, but that's what is probably going on. But, then again, I'm not a doctor.
 
I appreciate your reply very much, and I fear that my lack of effect was premature. I am experiencing some minor visual distortions but I am lucid, it seems. I splashed around in the bathtub for a bit...I'll see how the evening progresses. Thank you for your response, Kapitan, I appreciate it muchly! *waves*
 
BlobSnail said:
I appreciate your reply very much, and I fear that my lack of effect was premature. I am experiencing some minor visual distortions but I am lucid, it seems. I splashed around in the bathtub for a bit...I'll see how the evening progresses. Thank you for your response, Kapitan, I appreciate it muchly! *waves*
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It's the celexa, and maybe you have another medication that affects your serotonin system. Get that shit out of your brain unless you're gonna flip out without it. You'll have much better trips if you do this I can almost guarantee. Also, a better life.
 
PinealGland said:
Awesome. Does anyone's toes go numb when taking 4aco? If so at a larger dose how bad does the numbness get?
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I'm not sure that it's the same phenomenon, but I often "lose touch with" various parts of my body on psychedelics. It's not so much a numbing as just realizing that I have no sensations from that area, I guess. Back when I was first starting out, I would constantly worry that I had pissed myself or something. These days, I kind of just accept and ignore it.
 
Kapitan said:
I'm not sure that it's the same phenomenon, but I often "lose touch with" various parts of my body on psychedelics. It's not so much a numbing as just realizing that I have no sensations from that area, I guess. Back when I was first starting out, I would constantly worry that I had pissed myself or something. These days, I kind of just accept and ignore it.
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I get a pins and needles loss of blood sort of feeling
 
On mushrooms I get what I call 'phantom feet'. During the peak it feels as if my feet don't exist. I tend not to move very much. It's not a numbness per se, but an extreme disconnection (an out of body experience localized to one body portion?).

Tom
 
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