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The Big & Dandy 4-AcO-DMT Thread - Act Four

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Maybe 4-Aco-DMT doesn't really have the time to get hydrolized, but with inhibition of MAO it does. The longer duration is to be expected. Also bear in mind that harmala alkaloids are psychoactive so they definitely bring a change to the nature of your trip. I guess you could describe it as a bit more nature-feeling, so maybe that's why it feels more mushroom-like to you

Others have noted that 4-Aco-DMT w/ harmalas is decidedly Ayahausca-like.
 
Yeah I never had the opportunity of trying Ayahausca, the harmalas were for if I ever had the chance. I wish I had that experience to compare this to. Thank you very much for the response on what is possibly going on.

Another thing I didn't mention is that I had the longest afterglow I've ever experienced. I was pretty wore out for a day after the experience, but I swear the afterglow lasted a good 3-4 days. My eye sight at night was also noticeably improved as well. Very refreshing experience that I believe everybody should get to try before leaving this earth.

The wife put on her lullabye pandora station connected to those colorful water dancing speakers during the peak and the feelings that I had were so incredible, words could never describe it...but yeah, it was totally hitting in waves. Something that 4-aco-dmt doesn't do on its own to me.
 
Last night at 26.6 mg fumarate salt went surprisingly well; meaning I still found it to have very low body load (minor chills and that's it). ++ at 20 minutes and +++ at one hour (although this was short lived and quickly went back to a ++ which lasted for about 6 hours in total).

Felt like ~4-5 g of dried Cubensis mushrooms, and I am comfortable pushing this to ~32 mg. In the absence of mushrooms, I would feel ok in substituting this. Definitely I felt this as less pushy/speedy.

Weed was on board, so maybe this accounted for the reduced chills? low body load.

Was able to reach the state where it felt as if all my body molecules were rotating clockwise and counter clockwise at the same time.

Tom
 
In regards to mao inhibition affecting the deacetylation to psilocin, i doubt its a contributing factor. Mao enzymes are completely different than deacetylase enzymes. But thats not to say it can't affect the pharmacological action of acetylpsilocin, with regards to rima maoi's from rue or caapi.

Though, mushrooms, 4-aco-dmt, and straight up dmt fumarate, when taken orally with harmala alkaloids, are all ayahuasca-esque, and from personal experience, have been some of the most fantastic/productive trips i've ever made.

They can get a bit bumpy at times, but one of my all time favorite psych combos, are extracted Caapi alkaloids or Caapi tea, and 4-aco, or extracted dmt fumarate. Its just something else.

Just start low, as it can get extremely intense if you don't account for the increased activity by the addition of a rima, theres a strong synergy/potentiation with harmala, and dmt and its alkaloid/synthetic 4-substituted/5-substituted cousins.

I took about 300mg of harmalas from a strong black caapi tea (extracted the same vine, so i kinda know the alkaloid concentration of the tea per gram of vine used), and 30m later, 25mg of 4-aco-dmt.

Probably the 2nd most intense trip i've ever had, only shadowed by my aya cherry popping with an unknown, eyeballed amount of freebase dmt (in retrospect, prob somewhere near 120-150mg), and 3.5g of rue ingested in gel caps 30m before the dmt.

In both cases, the visuals were unlike anything I've ever experienced before, and psychologically, not for the inexperienced/unprepared tripper. Though, usually the rough come up ends at the purge, or fades if you don't purge. In some ways, its easier after that point than if you were to just take some mushrooms, or acetylpsilocin. Harmalas are a highly underrated psychedelic in their own right, as well as combined with dmt, mushrooms, mescaline, or 4-aco-dmt. But i don't take it with anything but those psychs, and acetylpsilocin, only because in all likelihood its just a psilocin prodrug, like psilocybin.

I've even heard postive reports with bufotenine and 5-meo combined with harmalas, but i don't think thats for me after trying bufo and finding it repulsive.
 
Yeah but the 4-Aco-DMT doesn't get broken down as fast (how does this work? MAO breaks of a chunk, then the enzyme for deacetylation breaks of a chunk, etc?) because MAO is inhibited and so the deacetylation enzyme has a bigger "chance" of getting this to psilocin. Seems rational IMO, but then again I don't have a Ph.D in pharmacology

I agree though, the power of the Harmala alkaloids is woefully underrated. The shamans seem to agree with this, and their knowledge of the Ayahausca experience is far beyond our understanding even though "we" have science
 
morninggloryseed said:
orally resembles psilocin but with a new color spectrum (reds vs blues and greens of psilocin) and a warm fuzziness vs the 'cold universe' feeling I get with psilocin. On the other hand, psilocin seems exactly the same whether IMed or taken orally.
Click to expand...
Also I have observed that shift colors, anyone can give some explanation or theory.
 
Tried 4-ACO-DMT fumarate a couple days ago and had a great time.
Mixed with it some alcohol and a lot of weed, then I finished off the experience with about 3mg Etizolam.

From the whole experience I can say that it felt like cleaner mushrooms.

No nausea, no weird feelings, not much anxiety, it was nice.
 
So I received an excellent batch of 4-Aco-DMT fumarate and 4-Aco-Dipt fumarate a few days ago. Mixing these two drugs went together very well. It's a pretty euphoric combination.

The visuals were great, body sensations were amazing. For me, it feels super energizing. Since I don't have a scale, I couldn't tell you the exact dosages that I took of each, but so far I've probably taken a larger dose of the 4-Aco-DMT with a lesser dose of the 4-Aco-Dipt. I suggest trying it out for yourself and finding the right mix.

All I can say is that this combo is definitely worth trying out for yourself. The headspace isn't too deep, but if you're looking for a great time then it is worth it. Either drug on its own is really great too. 4-Aco-DMT and 4-Aco-Dipt are definitely the best RC tryptamines that I have ever tried.
 
I've now taken 4-AcO-DMT.fumarate orally 5 times, ranging from 10.0 to 26.6 mg in the following order (and have some comments).

June 14 - 10.0 mg - lasted 2hr 50m. Euphoric, sedating. Had a lot of power yawns. Very mild visuals. A bit of the shivers. No stomach/GI distress. Alerts at 20-27m
June 21 - 18.2 mg - lasted ~4 hours. peak from 45m - 1hr 30m. Slow decline after that. Mild stomach pain. By 20m I was experiencing color shifting, haloes and visual patterning.
June 22 - 15.0 mg - was unprepared for this. took on a full stomach and didn't start to take effect for about 90m. Uncomfortable CEV's.
June 28 - 26.6 mg lasted about 6 hours total (peak from 1-2hr) - first time with weed on board. mild body buzzing by 7m, light sensitivity at 17m, intense body buzzing at 29m, OEV's interfered with me moving about.
July 6th - 16.2 mg - lasted about 3-4 hours. at 20m there was a mild body buzz and then I was surrounded by neon pink, yellow and green haloes.

4-AcO-DMT seems to be a very gentle compound. Unlike mushrooms, stomach upset was minimal or non existent. Most times I am able to eat ~3 hours after dosing 4-AcO-DMT. At least within the range of weights that I tried, the experience last from slightly less than 3 hours to slightly more than 6 hours. Strong, intricate OEV's started at about 16.2 mg and did not substantially increase out to 26.6 mg (although the length of the trip did). At 18.2 mg a strong body buzz feeling like an electric current ran throughout my entire body. This was not unpleasant and did not manifest as tremors like I experienced on 4-HO-DiPT. Taste was absent (sample dissolved in water and added to diet soda), although by the 5th trip I though I could imagine a slight bitterness.

There will be time for pushing it to a higher dosage, but for now I find it quite rewarding in the 16-26 mg range.

Tom
 
^It's surprising how active 10-15mg is, didn't find dosages around 20mg that much more powerful in fact (just more visual). Higher up on the ladder it's an entirely different beast though :)

Wouldn't exactly call 4-Aco-DMT gentle though, just very benign. There are easier headspaces to work with, though given the class and analogues that is to be expected
 
kidkimix; I should have been more specific. When I say gentle, I mean the apparent absence of vasoconstriction, bp increase, soft GI effects and little or no hangover.

For psychedelic headspace I've only had 4-AcO-DMT, 4-HO-DiPT and mushrooms for comparison. I'm not really sure how I feel about 4-HO-DiPT, and mushrooms....well I love them. But they cause me quite the upset stomach and irritable GI.

The only comparison I have is that when 4-AcO-DMT is over I feel mild regret and complete relaxation; when 4-HO-DiPT was fading away I felt relief, having found it unpleasant.

What do you mean by easier headspace? (less confusion, less anxiety, more able to control yourself). I've heard of the term, but am not sure exactly what it means.

thanks for the comments.

Tom
 
Odd, i find in terms of psychadelic head-space, the easier to manage 4 subbs i've had were 4-ho/aco-met, and 4-ho-mipt. Acetylpsilocin was a close third, and mushrooms coming in last.

In terms of physical affects, the easiest ones for me to take are 4-ho-met, 4-ho-mipt. Though i've not pushed my doses very high with any of the 4 subs, mushrooms and 4-aco always seemed to have a worse physical come up, but like i said, this was at doses no greater than 25mg.

Even though met/mipt is more stimulating than the dmt's, for some reason its easier to slip into the trip, and more physically comfortable to. But that could be psychological, considering the trips i've had with dmt and its derivatives, in high doses, that were by no means a walk in the park.
 
this is random, sorry.,
but I have been storing 2g of this stuff in a double baggie, then with a desiccant packet, then vacsealed. Placed into tupperware, into freezer.
This was over a year ago. My sample hasn't changed at all. It is the fumurate and the brown batch. It has not degraded at all. 30mg will blow somebody's mind really hard.
Will this stuff last years?
 
waferz said:
this is random, sorry.,
but I have been storing 2g of this stuff in a double baggie, then with a desiccant packet, then vacsealed. Placed into tupperware, into freezer.
This was over a year ago. My sample hasn't changed at all. It is the fumurate and the brown batch. It has not degraded at all. 30mg will blow somebody's mind really hard.
Will this stuff last years?
Click to expand...

Should. Just let it warm up before opening it, to prevent condensation on the cold packaging/substance, and replace the desiccant every few months. Also, I'd wrap the inner bag in foil, and toss in an oxygen desiccant as well.

No reason why that shouldn't last a decade or longer.
 
Yes, all of the 4-sub ts seem stable in a glass vial...some are 13 years old, all have never been opened until room temp, and all with a few silica beads, sometimes frozen they were frozen, sometimes not.

waferz said:
this is random, sorry.,
but I have been storing 2g of this stuff in a double baggie, then with a desiccant packet, then vacsealed. Placed into tupperware, into freezer.
This was over a year ago. My sample hasn't changed at all. It is the fumurate and the brown batch. It has not degraded at all. 30mg will blow somebody's mind really hard.
Will this stuff last years?
Click to expand...
 
Thomas Davie said:
What do you mean by easier headspace? (less confusion, less anxiety, more able to control yourself). I've heard of the term, but am not sure exactly what it means.
Click to expand...

Yeah those, pretty much. Headspace is just the mental aspect of the trip, what makes this rough for me is the curated thinking process and if the setting is not perfect there's a general restlessness. Of all the psychs I've tried so far, this one seems to be the easiest to go down south for me.

Not that I don't love this chemical, it gets me further away than any other. Just have to take care as to where and when I'm taking it.
 
^4-AcO-DMT/mxe is a special combo indeed, it seems to give me a special ability while tripping. I may just play too many video games or it may be a touch of delusion from the mxe but when I insufflate 40-50mgs of 4-AcO with 30-40mgs of mxe I seem to be able to control my OEV's. For example, I was watching the fibers of a bright orange towel draped across the bathtub morphing when I silently commanded "Show Me More". The morphing turned into a full blown war between two primitive tribes, this lasted for several minutes until they killed each other and some of them ascended to heaven in the form of a blue aurora above the towel and some them descended to hell in the form of a red aurora below the towel.

I seemed to be able to command my visuals through out the whole night. I've always been able to influence closed eyed visuals, but never OEV's. Good Stuff..
 
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Oh ROXIanne! said:
^4-AcO-DMT/mxe is a special combo indeed, it seems to give me a special ability while tripping. I may just play too many video games or it may be a touch of delusion from the mxe but when I insufflate 40-50mgs of 4-AcO with 30-40mgs of mxe I seem to be able to control my OEV's. For example, I was watching the fibers of a bright orange towel draped across the bathtub morphing when I silently commanded "Show Me More". The morphing turned into a full blown war between two primitive tribes, this last for several minutes until they killed each other and some of them ascended to heaven in the form of a blue aurora above the towel and some them descended to hell in the form of a red aurora below the towel.

I seemed to be able to command my visuals through out the whole night. I've always been able to influence closed eyed visuals, but never OEV's. Good Stuff..
Click to expand...
Just dose the 4-aco-dmt orally and time the come up with the insufflated MXE. You're wasting lots of money by insufflating this stuff.
 
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