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Dissociatives The Big & Dandy 3-MeO-2′-oxo-PCiPr (MXiPr) Thread

Hey folks..

Got a gram of this in Canada today.

Just did an unknown amount I'll guess 40-50mg under the tongue.

It made my tongue and mouth so glad damn numb.

It's consistency is slightly pebbly powder. Numbs the mouth greatly don't think it's caustic though.

I'm slowly slipping into a warm feeling ..

In twenty mins I'll snort a line and see where I end up, if the sublingual original dose dose not hit hard enough - I did do 250mg DMXE via IM yesterday.

Also took about 1mg Flunitrazolam twelve hours ago.

As the time goes on I feel more warmth coming on. Feels very good and content. Music is so nice sounding. Wow.

Have lots of experience with old school MXE, pcp analogs, tons of dissos. I need a scale so that I can weigh out proper doses to do some detailed trip reports for the community.

I've been in the scene for fifteen years almost and stilll going strong contributing to the cause.

A very good mood boost experience right now. I'm in a very happy mood and my feet are tingly. My tolerance may be a bit high so I will do a nasal dose soon, and then take a week break and follow up with more reports.

I have five or six dissos in my possession right now, some of which are this, 3-ho-pce, DMXE, O-pce. Various routes of administration but I am planning on doing more IM injections once I get a scale. Have a few needles now though but 25g leave my muscles hurting day later maybe not doing proper technique.


Yeah I'm gonna have to do a higher nasal dose of this then I'll put it away for tolerance to wane. The earlier benzo use and prior intramuscular DMXE use yesterday probably has made my tolerance sky high.
 
I holed on MXiPr a couple days ago in combination with the perfect amount of edibles and nitrous and it was amazing.

I'm not particularly experienced with dissos; I've holed on ketamine and combined DXM up to a second plat with a number of psychs including DMT. No tolerance. Ketamine has been known to make me puke from motion sickness so I took a ginger pill to be sure (and didnt experience any nausea). I didnt measure out my doses, instead opting to sniff small lines and wait for the come up to start before taking my next small line. To be honest, this definitely feels like the way to go for me.

I had been chilling and feeling the drug out for an hour already. The music I was listening to gave the perfect mood as I sat back in my chair. I hit my last line and took a breath out of my nitrous canister. The next few minutes slipped by me as I floated deeper and deeper into a dream, not even aware of how far dissociated I was until I was no more. Full ego death, moments of eternity, impossible to describe. Coming back, I began to grapple with the universe around me observing everything in a vacuum starting with time. A multidimensional mesh of time that I happened to be moving through linearly. Why? I began to question who I was. Everything I had once known and taken for granted was now an independent variable I had to rediscover. I saw myself as a being with aspirations and saw the paths through time I could take to accomplish them. I redosed again and repeated the process with no magic lost.

I sobered up enough and decided I needed some sleep I crawled into bed around 3AM, around 2 hours from when I started and 1 hour since I started going hard. I think I fell into a very light sleep here until 7AM where I woke up to me stroking my own arm (I recently got tattooed in that spot so it felt good). My head was spinning and pounding and I was dehydrated. I drank some water and that really helped my headache. I eventually managed to fall asleep until 2PM where I spent the rest of my day tired. A lot of the trip was hard to remember. I'd probably dose sooner next time.

TL;DR:
This might be my favourite new drug, definitely favourite dissociative of the three I've tried (lol). Seems to be sedating enough to hole and chill out on. Heavier doses can lead to ego death, at the very least with the aid of cannabis and nitrous. Seemed less likely to make me feel nauseous than Ketamine but this might've been the ginger I took. Will definitely be continuing with this chem.
 
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So what’s the consensus on oral/sublingual with this fine goddess?

it seems fairly potent and I’ll be volumetrically portioning it out (no scale I usually get pellets or blotter)

I’d like to dissolve 2g into 30ml of PG. will probably start with a 33.33 mg dose or .5ml of the solution sublingually. For tolerance I have basically none, only do dissos like once a week tops and 100mg of ket will usually hole me.

edit: also anyone trialed mixing this with a 4-sub tryptamine yet?
 
I holed on MXiPr a couple days ago in combination with the perfect amount of edibles and nitrous and it was amazing.

I'm not particularly experienced with dissos; I've holed on ketamine and combined DXM up to a second plat with a number of psychs including DMT. No tolerance. Ketamine has been known to make me puke from motion sickness so I took a ginger pill to be sure (and didnt experience any nausea). I didnt measure out my doses, instead opting to sniff small lines and wait for the come up to start before taking my next small line. To be honest, this definitely feels like the way to go for me.

I had been chilling and feeling the drug out for an hour already. The music I was listening to gave the perfect mood as I sat back in my chair. I hit my last line and took a breath out of my nitrous canister. The next few minutes slipped by me as I floated deeper and deeper into a dream, not even aware of how far dissociated I was until I was no more. Full ego death, moments of eternity, impossible to describe. Coming back, I began to grapple with the universe around me observing everything in a vacuum starting with time. A multidimensional mesh of time that I happened to be moving through linearly. Why? I began to question who I was. Everything I had once known and taken for granted was now an independent variable I had to rediscover. I saw myself as a being with aspirations and saw the paths through time I could take to accomplish them. I redosed again and repeated the process with no magic lost.

I sobered up enough and decided I needed some sleep I crawled into bed around 3AM, around 2 hours from when I started and 1 hour since I started going hard. I think I fell into a very light sleep here until 7AM where I woke up to me stroking my own arm (I recently got tattooed in that spot so it felt good). My head was spinning and pounding and I was dehydrated. I drank some water and that really helped my headache. I eventually managed to fall asleep until 2PM where I spent the rest of my day tired. A lot of the trip was hard to remember. I'd probably dose sooner next time.

TL;DR:
This might be my favourite new drug, definitely favourite dissociative of the three I've tried (lol). Seems to be sedating enough to hole and chill out on. Heavier doses can lead to ego death, at the very least with the aid of cannabis and nitrous. Seemed less likely to make me feel nauseous than Ketamine but this might've been the ginger I took. Will definitely be continuing with this chem.
Excellent. Did you experience any sense of anxiety with the ego death ?
 
Possible serious warning.

I boofed basically the whole half gram in about two days and had some very weird side effects on the last night. And mind you, I had not washed any of this stuff so it could just be from the impurities being fucked or some.

I was staying the night at a buddy's house, n had done my last dose before he picked me up. The night was awesome, but I was dosing tons of etiz and drinking too. I have permanently damaged GABA receptors, so for some reason I'm able to eat straight powder n not black out. ANYWAY

While trying to sleep, I had the worst muscle jerks I've ever had in my entire life. Worse than EXTREME benzo withdrawal (more than seizure level)

I was completely unable to sleep due to this and ended up taking my last 15mg or whatever it was of etiz, just for some relief. The jerks were something like my legs shooting STRAIGHT up. I was constantly uncomfortable and changed where I was sleeping almost every 15 minutes. Actually at one point sleeping beside my other buddy's air mattress n he pet my head thinking it was his cat LMAO

anyway. Really fucking weird, n with some other chems involved who can really say. Just wanted to relay my experience.

Stay safe, all. I will most likely be ordering more, but washing it.
 
Excellent. Did you experience any sense of anxiety with the ego death ?

Not at all! Funny since usually pot will make me a little uncomfortable and would make ketamine feel a little weird and funky (not necessarily in a bad way). With MXiPr the hole and ego death was welcome. Even if it was uncomfortable at times it just seemed like there was no use resisting. Everything would turn out alright. I had total trust in the molecule. Everything just felt right.

I will likely give it another test Sunday or Monday and see if I can replicate this feeling and experience with any consistency and report back here. I'll try to record the first half dozen or so doses. I tend to dose light but often so I may eyeball the rest of my doses if I don't have enough to get me to a hole. I find it too hard and too distracting to use my inconsistent scale when I'm all wonked out.
 
Not at all! Funny since usually pot will make me a little uncomfortable and would make ketamine feel a little weird and funky (not necessarily in a bad way). With MXiPr the hole and ego death was welcome. Even if it was uncomfortable at times it just seemed like there was no use resisting. Everything would turn out alright. I had total trust in the molecule. Everything just felt right.

I will likely give it another test Sunday or Monday and see if I can replicate this feeling and experience with any consistency and report back here. I'll try to record the first half dozen or so doses. I tend to dose light but often so I may eyeball the rest of my doses if I don't have enough to get me to a hole. I find it too hard and too distracting to use my inconsistent scale when I'm all wonked out.

yea, that sounds perfect. even though working through fear and anxiety as you pop through the levels has been an integral part of the psychedelic experience, I feel that at a certain point it’s just an annoying distraction/barrier to truly engaging with the deepest levels of experience. my best shroom trip was like that, just peace and acceptance, and no attachment to either the fantastical or hellish visions - it was kind of just , oh yea, there those are again,cool, if you know what I mean. Then you just surf the waves.

naturally I’ve found it hard to recreate that special sense of wholesome apathy lol. Not much experience with dissos let alone research chemicals. Don’t have cool enough friends I guess haha 😆

Have a great time today or tomorrow mate! We’re looking forward to reading the report !
 
Have many people tried mixing this bad bitch w/ psychs? I'm really excited to try taking hits of freebased DPT mixed with pot while on this stuff
 
So what’s the consensus on oral/sublingual with this fine goddess?

it seems fairly potent and I’ll be volumetrically portioning it out (no scale I usually get pellets or blotter)

I’d like to dissolve 2g into 30ml of PG. will probably start with a 33.33 mg dose or .5ml of the solution sublingually. For tolerance I have basically none, only do dissos like once a week tops and 100mg of ket will usually hole me.

edit: also anyone trialed mixing this with a 4-sub tryptamine yet?
Bout the 4-subs, I'm planning on ordering more real soon n will definitely have to test that out.
 
Dissos and psychs are a winner combo. It should work fantastic. Just cut in half every dosage as they tend to sinergize/multiply each other
 
Anyone know if this is safe to combo with a MAOI? I have Changa (DMT+MAOI) on hand and I'm willing to go for it. I almost did it during my latest experience but stopped myself when I remembered the implication of trying a combination without looking up if they're even safe to combine.

Also I wont be posting a detailed trip report for my last experience but I have to say that was by far the most intense dissociative hole I have ever experienced. I definitely went through a few stages of understanding and accepting my own death. My entire existence and perception of time and space just folded away. The closest thing I could relate it to other than ketamine would be Salvia except with even less ability to perceive and just enough euphoria for me to feel okay. Not enough to spare. After my ego death I crawled into bed in my confusion trying to understand where/who I was, what was going on, if I had work in the morning or if I was supposed to be doing something. How I got there and if what I was feeling was normal and how it's always been. I just layed there in the dark as my life slowly came back to me like a dream I had forgotten but was remembering. Eventually I fell asleep. As crazy and kind of terrifying as it was, I definitely enjoyed it and will be repeating the experience.

I will say I think I also noticed a little sharp pain in my lower back, maybe indicating some strain on my kidneys.
 
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I don't THINK dissociatives are affected by MAOIs but please don't take my word for it, as I'm not positive.

I'm getting the sense that MXiPr can be really serious and amazing at the right dose.
 
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(Here's an edited version of my previous post.)

As mentioned earlier in the thread, I did an an acetone wash on mine and transferred it to a glass vial before trying it, since I found the burnt plastic smell genuinely worrisome. The product no longer smells of anything, although when taken orally the taste is similarly unpleasant.


TRIAL #1

Orally dosed about 22mg, First alerts felt around +0:15. Tactile sensations enhanced. Slight headache felt on the top of my skull, but nothing unbearable (it subsided without my noticing it). It quickly became clear that this was indeed a dissociative, and that this dose was on the low end.

Re-dosed around 20mg at +0:50. Effects become more pronounced. Was chatting with my closest friends and giving my impressions.

I did not keep track of time, but I soon became wobbly and more and more dissociated. Ketamine is the only other dissociative I have experience with, but it provides an excellent point of reference. Whereas ketamine is cold and clinical, this provides a warm, comforting euphoria that I was somewhat surprised by (although I was expecting it from reading other reports).

Now I found myself understanding why some people really like dissociatives. At last I understand the abuse potential (from the chat: "somehow i feel like until now i was mostly being polite in my appreciation of k. now i fully get why one would become a disso fiend"). This is almost too nice to have no downsides. I also write:
"to make a really wonky analogy: this is to k what an indica is to a sativa". Other aspect that makes this a clear winner over ketamine: no nausea.

Speaking of weed, made one bad decision around the +2:00 mark and had a few tokes of an indica joint (I know, much
too soon). Shit got intense for about 5-10 minutes and I had to lie down. The strangeness of dissociation and thoughts on the potential for abuse (and all the weird societal guilt associated with it), as well as an uncomfortable sensation in my lower back almost completely killed the previous euphoria and sent me in a somber mood.

Nevertheless, I set about to try working on music in that state, and I guess this is where the more manic side of the drug proved useful. I already had a setup ready to go for recording, so I just hit record and jammed with something I'd been working on in the past few days. I found myself nicely uninhibited and driven to complete at least one take of this one track.

The rest of the night was uneventful. I didn't sleep long, but upon waking up I felt quite relaxed and content. This has clear immediate antidepressant effects. The sensation in my kidney/lower back, however, did not go away for a good couple of days (I'm not sure it even fully went away). I drank lots of water and green tea. Then I tried to convince myself it was muscular.


TRIAL #2

Four days later, I decided to plug 25 mg.

This time the effects came on stronger and faster.
This time around I found the difference between this and ketamine to be more subtle. The actual dissociative aspect, the feeling of being "far away" inside my body, was almost identical.

At around +1:30 I decided it was time for a redose, and plug about 30mg more.

I decided to throw on a non-narrative movie. Every tableau felt fraught with deep, quasi-mystical meaning that resonated with current happenings in my own life. Many absurd associations and mini-epiphanies were had. I believe I was on the verge of a hole the entire time, and briefly forgot I was on a drug (or what a drug was), thought that the film and the drug were one and the same, etc. Classic delusions.

Again, at the most acute part of the experience, this was something I'd describe as a more euphoric, non-nauseating ketamine-like high (comparable to 40-50 mg IM).

This time around I experienced no immediate physical discomfort, no headache. Interestingly at one point I burped, and briefly tasted that weird burnt plastic taste. I noted a strange dry-but-sweaty sensation on my hands, also characteristic of a decent ketamine dose. Tinnitus was also present both times the acute effects manifested themselves.

I went to bed at about +5:00 and woke up about 6 hours later, again feeling a nice afterglow. This time, the uncomfortable sensation in my lower back returned, so I've been drinking lots of water. It is still lingering 3 days later. While it's not exactly painful, I am worried I may have damaged my kidney to a certain extent.

So yeah, it looks like this drug might indeed consistently prove a strain on the body.
I did also experience, like one of the posters above, mild spasms in my inner thighs on a few occasions in the days following the last dose. They fortunately didn't return today.

The good news is bladder function seems completely unaffected: no pain, no difficulty, no change in frequency or urine appearance/smell.

Well, there you have it. The immediate psychoactive effects are everything I was hoping for, but the physical side effects are alarming. Currently debating whether I should get rid of what I have left, because this being a dissociative, the temptation to say fuck it and just ingest it anyway is also quite real.

I know the novelty aspect is quite alluring, but I can't say I recommend putting your health at risk with such a new and unknown substance - at the very least with the batch that's currently in circulation. Needless to say I feel silly for not waiting longer before deciding whether to order this or not.

I encourage anyone who can to send in samples for analysis. I'm hoping to get this done soon.
 
All the ACH dissociatives are. The higher the dose, the worse it seems to be. Ketamine seems to fuck people up the worst because people are doing grams a day. The RC dissos tend to be way more potent. But still, yeah, they're all bad for your kidneys/bladder.
 
All the ACH dissociatives are. The higher the dose, the worse it seems to be. Ketamine seems to fuck people up the worst because people are doing grams a day. The RC dissos tend to be way more potent. But still, yeah, they're all bad for your kidneys/bladder.
Touch wood, i rarely get kidney pain from k, like almost never, even I've been a proper bender (i class a proper bender as 25g in a few days)
I do take quite alot of supps/vits when i am binging though (but nothing kidney specific - i take strong cranberry extract for my bladder, little pills that are the equivalent of 5g dried berry, I take 2 daily, aswel as turmeric, omega3 oils, strong multi vits, garlic, magnesium, iron, zinc, extra vit c+d) and always drink plenty of fluids. And eat hot chilli every day as an antioxidant, even if im not eating ANY food, ill eat a spoonful of chilli 😋
 
Ketamine has never given me kidney pain either, but it clearly affects my bladder (dull throbbing pain that comes and goes for a few days), and I've never gone on binges -- most I've done in one sitting is about 100mg, and I don't think I've ever taken it two days in a row. I always revert back to normal if I abstain. It's also possible that I'm particularly sensitive to dissociatives.
Anyway, I'll report back when this hopefully goes away.
 
Touch wood, i rarely get kidney pain from k, like almost never, even I've been a proper bender (i class a proper bender as 25g in a few days)
I do take quite alot of supps/vits when i am binging though (but nothing kidney specific - i take strong cranberry extract for my bladder, little pills that are the equivalent of 5g dried berry, I take 2 daily, aswel as turmeric, omega3 oils, strong multi vits, garlic, magnesium, iron, zinc, extra vit c+d) and always drink plenty of fluids. And eat hot chilli every day as an antioxidant, even if im not eating ANY food, ill eat a spoonful of chilli 😋

Didn't you say you once had really bad problems with your bladder and K? What changed? Did you just take a break and don't use as much now?
 
Didn't you say you once had really bad problems with your bladder and K? What changed? Did you just take a break and don't use as much now?
Yeah I nearly lost it, was pissing blood, bright green bloody shot, black blot clots 50+ times a day no exaggeration, constant 10/10 pain, ket bladder syndrome, ulcers ket cystitis, mass fibrosis, uti, etc, did a month clean in rehab with 3.5 weeks of Co-amoxiclav to clear the infection and oxybutyn 3 times a day, plus codeine paracetamol naproxen and diazepam for pain, promethazine at night, and started using again as soon as i left rehab, but no where the amounts I was doing.
It was before i injected, i was selling it, and selling coke, so endless supply, going through minimum 10g of k, more like 15-20g a day. Literally id wake up get my frying pan and take a biiig pinch 2-3g of crystal, not even cook it, rack it into 5 or 6 lines, do them one after the over, to kill the pain i was in BECAUSE of the k. It was a vicious cycle. And the last 3 months before rehab i was mixing coke into my lines which would make my throat numb and i wouldn't realize that i was swallowing the k drip, im sure this played a major factor, because I was always MILITANT with spitting.
That and some super strong chinese s isomer 'big ball' i blame those 2 factors.
Because i did 10-15g a day for years n years with very little break (i sold it for a long time) and never got that bad.
Also back then, i didnt take vit or sup, didn't drink water, didnt eat properly, didnt sleep properly. I was sofa surfing/hotelling, selling, be awake for 3 days at a time, not eat, sleep a few hoirs, eat a shitty meal deal, repeat. All factors

But yea now i just supplement, eat well, sleep well, plenty of fluid, n barely snort, just inject.
 
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