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The Big & Dandy 2C-E thread (Reorganized)

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insufflated dose/response curve

A few questions for people who have had lots of experience with this compound nasally:

1. what's insufflated dose/response curve like?

2. Do you do it all at once, or do you stagger the dose over 10 or 15 minutes, to smooth the come up a bit?

3. If you find you're not where you want to be, have you tried boosting your initial nasal dose early on, say within the first hour?

I'm contemplating the following regimen: 5mg insufflated, then another 5mg 10 minutes later. Then potentially boosting by 2mg an hour in (by which point I'd think the effects of the initial dose would have fully manifested). And if I'm still not where I want to be, possibly even another 2mg at 90 minutes or so.

In theory I like the idea of sticking with your initial dose, taking whatever is given to you, etc. But in practice I have a limited time window in which to trip, so I don't want to expend a day on a lackluster experience and then have to wait for tolerence to reset in order to try again.

thanks -S/M
 
Xorkoth said:
If you're taking it orally, it will be about 10 hours probably. 8 hours would be the minimum I could imagine it having an effect, so maybe at 10mg you could have 8 hours, but I would estimate high at 10 hours just in case.

Geist: Snorting 2C-E is going to make it much more intense. I really do not recommend taking it for the first at a concert, and I especially do not recommend snorting it for your first time at a concert. It will be shorter but it will also be more ferocious... 2C-E can be an extremely serious psychedelic.
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Agreed. I've had fairly extensive experience with 2C-E, and although every time I've taken it I've had an awesome time, 2C-E is something I feel deserves extra special attention to set and setting in order to be rewarding. Most times I have done 2C-E it's been orally, but the few times i have done it rectally (similar potency to snorting) it's hit way faster, harder, and has defintely had a more "psychedelic whack on the head" quality. The visuals were way more intense, and i was getting body rushes that were really intense. I was just in my room alone for this trip, so i was able to get comfortable like that, but i couldn't really imagine doing anything else. That was 12 mg rectally, powerful stuff. I think 16 mg orally is QUITE adequate for a concert event. I'd say even 10 mgs will be extremely noticeable if you go out into a public environment on 2C-E. Actually I find that with all psychedelics, that if you can take whatever dose alone in your room or other similar controlled/comfortable environment, then half that out in a public area is just as powerful with all the added stimuli and added chaos an unpredictability and what have you.
 
A friend and I were getting ready to snort some 2C-E for the first time. He took a line first. I watched his reaction.

Then I decided to dose mine orally.

Peacelove,
Aldousage
 
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Delsyd said:
after reading your first sentence i was going to warn you against snorting it.

...then i saw i wisened up.

peace.
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Have you snorted it? If so I'd appreciate any answers you could give to my questions a few posts up. Thanks.
 
I really want to try this chemical, but I'm not sure how to ingest it...from what I've read it sounds like snorting it is very intense/painful, meanwhile orally dosing it seems like its awesome, but very long, like LSD (which isn't too big of a factor for me)

I've taken pretty high doses of LSD on plenty of occasions, in the 500-600 and even up to 800 mics at a time, but it sounds like 2C-E is just as intense as a high dose of acid and if I snort it I'm going to be blown out of the water...is this a safe assumption guys?

At the same time, if I were to take it orally could I just mix the powder with a drink? or just place it onto my tongue and take a drink and be good? Taste doesn't matter and I don't have any gelcaps to make a pill with. I'm thinking of starting at either 15mgs or 20mgs..I know that may sound like a lot to some people but I always like to go big or go home with awesome psychedelics, and like I said I've had plenty of experience with being WAY out there.

So what do you guys think? snort or swallow? and at what dose for each? I'll be doing it alone the first time since thats how I always do psychedelics for the first time...
 
Parachute it. Take a single square of TP, and if it's two-ply or something, separate the two layers, and then tear off a smaller square. Put your powder on it and twist it up. Get a mouthful of water or what have you, drop the "parachute" in and swallow. I do it this way because putting the parachute in first can cause it to stick to your tongue.

2C-E honestly doesn't taste that bad though, but it depends on your personal taste buds whether you'll want to take it straight. The only RC I consistently parachuted was 4-HO-DIPT. I described the taste to my girlfriend as, "Drinking a shampoo dacquiri out of a squirrel's ass."

Snorting it is both painful (for most people, but there are a lucky few it doesn't seem to bother) and very intense, but it also became my preferred method of administration. The rush was definitely a big factor for me, and the time dilation was just incredible. I could snort my bump (usually 8 or 10mg, but start at 5-- seriously) and 10 minutes later I could look at a clock, and, after remembering what it was and how to read it, be amazed at how little time had gone by...

Anyway, enough retrospective. For your first time always go with old faithful-- oral admin. I'd just recommend that you try snorting it at least once at some point in your "career" with it. It's worth experiencing, especially since you seem to like higher doses of LSD.
 
^^^

thanks for the info, I will defiantly try snorting it at some time...maybe my first time, but it sounds like taking it orally might be the best choice for my first time. I think its a good idea to start low with the snorting too since I rarely snort many psychedelics, although I'm really looking forward to trying this one...
 
Yeah, to iterate the very last bit of my post, I definitely recommend sticking with oral admin for your first time with psychedelics traditionally taken that way. I'd start oral with 15 or 16mg for a gentle intro, or 18mg if you want something stronger. Not sure how much you've read, but 2C-E's dose response curve is non-linear. The jump from 18 to 20mg is much much stronger than the jump from 16 to 18. Ditto as you go up from 20. I found that for me 10mg snorted or IM was equivalent to about 25mg orally, but with incredibly rapid onset and shorter duration. Still, that's very very very very intense, and I'd done a ton of experimentation with oral (rawr!) before I made that jump.

2C-E is a really sweet girl, and it's worth taking the time to court her and establish an intimate relationship before you break out the whips, chains, and cattle prods.

Oby Enterprises-- Sodomizing Metaphors Since 1982.
 
I tried 40mg-ish of 2C-E Oral, and while it was quite intense, especially visually, I dunno I don't really notice anything overwhelmingly transcendent if you know what I mean. I keep hearing about these ++++ experiences and merging with the cosmos but I don't really get that? Do I need a higher dose? or perhaps another route of administration? I should try snorting or plugging it. Anyone else have any ideas? Also just another question, How stable is 2c-e in water? or does it degrade fast?
 
Excido said:
I tried 40mg-ish of 2C-E Oral, and while it was quite intense, especially visually, I dunno I don't really notice anything overwhelmingly transcendent if you know what I mean. I keep hearing about these ++++ experiences and merging with the cosmos but I don't really get that? Do I need a higher dose? or perhaps another route of administration? I should try snorting or plugging it. Anyone else have any ideas? Also just another question, How stable is 2c-e in water? or does it degrade fast?
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Phenethylamines are very stable in water from what I've read. You may want to try plugging. I didn't find 2C-E transcendental until I plugged 50 mg, was alone and in the dark with Pink Floyd and Astral Projection.
Be careful though, 2C-E gave me some HPPD for about a month or two after high doses.
 
Excido said:
I tried 40mg-ish of 2C-E Oral, and while it was quite intense, especially visually, I dunno I don't really notice anything overwhelmingly transcendent if you know what I mean. I keep hearing about these ++++ experiences and merging with the cosmos but I don't really get that? Do I need a higher dose? or perhaps another route of administration? I should try snorting or plugging it. Anyone else have any ideas? Also just another question, How stable is 2c-e in water? or does it degrade fast?
Click to expand...

As Erebus said, it's quite stable in water. But remember to use demineralized water as tapwater easily become infected or rotten. Maybe you should try dissolving it in alcohol instead. It will be quite stable this way and will last for years because of the alcohol. You can use 96% proof, but vodka will do :)

As for the experience you had; IME 2C-E goes quite deep, but I don't think its compareable to LSD for instance. I've had some fairly intense experiences with 2C-E, but nothing nearly as deep as some of the experiences I've had on LSD. I guess we all react differently.
 
Obyron said:
Snorting it is both painful (for most people, but there are a lucky few it doesn't seem to bother) and very intense, but it also became my preferred method of administration.
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Hey Obyron, since you seem to have experience with nasal ROI, could you take a stab at the questions I posed above. Here they are again for convenience:

1. what's insufflated dose/response curve like?

2. Do you do it all at once, or do you stagger the dose over 10 or 15 minutes, to smooth the come up a bit?

3. If you find you're not where you want to be, have you tried boosting your initial nasal dose early on, say within the first hour?

I'm contemplating the following regimen: 5mg insufflated, then another 5mg 10 minutes later. Then potentially boosting by 2mg an hour in (by which point I'd think the effects of the initial dose would have fully manifested). And if I'm still not where I want to be, possibly even another 2mg at 90 minutes or so.

thanks -S/M
 
1) As steep as oral, but not as noticeable because the numbers are smaller. So 10mg is more than twice as strong as 5mg. Personally 5-10 was the ideal dosage range for me. For me 5mg was a sustainable +2 that I could function on. 10mg was a powerful +3 (I never had a +4 on 2C-E) that pretty much had me munted for hours. I would dose in between accordingly.

2) I'm one of the unlucky fucks for whom it BURRRRRRNS. There is no way I'd stagger it out or try to force myself to do it twice. I'd usually spend the first 5 minutes wanting to claw my nose off, and by the time it would subside to a dull throb I would realize how incredibly fucked up I was.

3) Never tried supplementing, mostly for the same reason I never tried splitting doses! But I also never had an occasion that nasal 2C-E didn't get me where I wanted to be.

Your regimen sounds fine, but give the 5mg about 15 minutes to be sure. Hopefully it won't be as painful for you as it was for me.

Good luck. :)
 
Thanks Obyron, that's really helpful. I actually have snorted 2C-E several times before, just never more than 6mg, which brought me to a mild but pleasant +2 (which oddly is further than I got on 25mg oral). I get the intense burn too, but breaking it into smaller bumps and spacing them over 10 minutes seems to mitigate it somewhat for me.
 
I can't really say anything for snorting 2C-E, but i don't think I ever want to snort it since I have tried it rectally. Seems to have all the pluses of quickly absorbing through mucus membranes, without the "wow my face is burning off" feeling. Also....careful snorting those chemicals that burn...i mean, you only have one sense of smell, and those mucus membranes can be delicate.
 
^^ I ran out of 2C-E long before I tried plugging it, which was a shame. I tried it oral, snorted, and IM, and all three were great. Wish I'd had a chance to do that before I ran out, because I can imagine it would have been fantastic.
 
snorting is dangerous, you'll wear holes in your face, and if you die, (you don't know that you won't) it will be another step towards criminalizing it.
 
So is IM 2C-E safe? I wouldn't mind trying it. As well as plugging, can anyone give me a quick rundown on how to plug 2c-e? :) How long does "it" feel uncomfortable after you plug? I've also heard when you do it its best to push it to one side due to some wall or something?
 
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