I been doing a good bit of research with this and the c version and lsz latley. I've found the combo of lsz and 25inboh is completely amazing at half a blotter each, but it's probably very foolish to mix them, but I can't say I experienced any negative effects. I also recently acquired recently the nbome version of 25i to compare, and the only difference to me was duration and body load, the nboh being far more pleasant. Visually and body buzz (load is the bad and buzz is the good in my lingo) they are extremely similar to me. Now that said, this clearly has different effects depending on who takes it. For me this is a great drug, highly remenicent of mescaline but with far less headspace, for my wife its overpowering in terms of body load, for my drummer its useless, and for my guitarist it was compared to E rather than a pure psychedelic drug like how I experience, so it's a strange beast.
At higher doses I've found 2mg to be as high of a dose as I'd wish to go, because it can feel quite toxic at any higher dose, even the teeniest sliver of a third blotter makes it a very pukey, tense experience. Basically, try it, it's either is amazing or its not, and keep your dosages low if you do indeed enjoy it.
One final note. The nbome has a completely ridiculous tolerance, but the nboh seems to be significantly less, in my experience. The nbome leaves me unable to trip for a week and a half at least, while the wait time for the nboh is 3-4 days and im good to go. I also did some experiments with 5ht supplementation and noticed that I do indeed experience stronger effects as long as you take it for a period of time before your next doseage. When not supplementing and taking a dose too early, there is a significant difference in intensity, perhaps this does not affect tolerance per say, but it restores your supply of serotonin more rapidly than you can do on your own so perhaps that's enough to affect the intensity of the trip, after all you still don't get the same punch in the head as if you wait till tolerance fades, just a better one than you would without supplementation.
Oh, bonus final note: had anyone experienced this: if you smoke weed, for example, the day or 2 after taking these drugs, it can retrigger the trip somewhat, giving visuals and a body buzz that is not at all characteristic of weed and is very much like the 25i nboh/nbome. Perhaps its some odd psychosomatic effect in my silly little head, but I certainly never expected to hit a morning bowl and then trip for about another 3-4 hours like I took a third of a blotter, lsd, mescaline and mushies never did that to me, although they all have an afterglow that enhances weed, they don't retrigger vivid hallucinations and that electric blood feeling that I love so much about the 25i. Just curious if anyone else noticed such an effect. Does it bioaccumulate in the brain or possibly not dislodge from the receptors for a more extended period than expected or something like that? Just things I've been thinking about lately...
Peace