Dissociatives [Methoxetamine Subthread] Combinations - 2nd experiment
- Thread starter Thorns Have Roses
- Start date
vortech
Bluelighter
The Neurobiology of Psychedelic Drugs analyzes and compares the effects of psilocybin and ketamine and gives insight into their synergistic effects when combined. Given the common mechanisms between ketamine and MXE (NMDA receptor antagonism), this research can also be of value for the other dissociative hallucinogens such as MXE to compare the effects to not only psilocybin but also other psychedelic tryptamines, given their common mechanism of serotonin 5hta receptor antagonism.
Ballz_Trippington
Bluelighter
Does anyone have an idea how long one should wait (how many days) to dose MDMA after an MXE trip? Or how long one should wait to dose MXE after tsking MDMA? I am attending a festival next week and this information is crucial. I also have a friend that takes codeine for a back problem and really wants to try MXE any idea if the codeine and MXE might be a bad idea?
Any expert advice would be immensely appreciated!
Any expert advice would be immensely appreciated!
Two days break in between would be more than sufficient in respect to your somatic health.
Ballz_Trippington
Bluelighter
So I got to try MXE in combination with LSD at a festival this weekend... The MXE dramatically altered the LSD experience. I had already taken MDMA on Wednesday (200mg), 4-AcO-MET on Thursday(15mg - very very low dose for me) and 4-HO-MiPT on Friday (30mg very low dose for me) so I knew tolorance would be a big factor.
I decided on 5 hits of good LSD and one 25mg bump of MXE ( this should not be recommended for MOST people - but I'm not most people).
I felt nothing from the LSD for the first 45mins then I did my bump of MXE and almost instantaneously I felt the acid come on! The entire experience only lasted about 3-4 hours after which I had a strong urge to go to sleep which I did in my tent at 3am on Saturday night at a huge festival which should have been impossible for me due to the LSD, MXE and insomnia I suffer from.
I had absolutley no visuals to speak of just this intensely powerful body high that was quite euphoric.
I had a friend who also tried 1hit of the acid and one 25mg bump of the MXE and said that he'd never felt so high in all his life but had no visuals to speak of. He also went to sleep early and at about the same time as me.
Very, very strange potentiation between these two chemicals! I also felt that the LSD seemed to potentiate the MXE as I felt myself slurring my words and robo-walking as if I'd done 100mg of MXE. I wonder if a second bump of MXE later on would have prolonged the effects as it seemed like the trip ended as soon as the majority of the MXE wore off.
I decided on 5 hits of good LSD and one 25mg bump of MXE ( this should not be recommended for MOST people - but I'm not most people).
I felt nothing from the LSD for the first 45mins then I did my bump of MXE and almost instantaneously I felt the acid come on! The entire experience only lasted about 3-4 hours after which I had a strong urge to go to sleep which I did in my tent at 3am on Saturday night at a huge festival which should have been impossible for me due to the LSD, MXE and insomnia I suffer from.
I had absolutley no visuals to speak of just this intensely powerful body high that was quite euphoric.
I had a friend who also tried 1hit of the acid and one 25mg bump of the MXE and said that he'd never felt so high in all his life but had no visuals to speak of. He also went to sleep early and at about the same time as me.
Very, very strange potentiation between these two chemicals! I also felt that the LSD seemed to potentiate the MXE as I felt myself slurring my words and robo-walking as if I'd done 100mg of MXE. I wonder if a second bump of MXE later on would have prolonged the effects as it seemed like the trip ended as soon as the majority of the MXE wore off.
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relbatnrut
Bluelighter
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- Dec 23, 2012
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Tell me about your 4-sub tryptamine combinations! I've done MXE and 4-ho-mipt once at low(ish) doses, and it was pretty cool. I'd like to venture further out with it next time.
Ballz_Trippington
Bluelighter
I've tried MXE with 4-AcO-MET at 40mg MET and 3or 4 - 25mg bumps of MXE and I barely even noticed the 4-AcO-MET. In that case the MXE just totally over powered the MET. There was no synergy at all in my experience.
Perhaps using less MXE or more 4-AcO-MET would have been more synergistic but whatever the case, it was the wrong amounts of each for me.
Perhaps using less MXE or more 4-AcO-MET would have been more synergistic but whatever the case, it was the wrong amounts of each for me.
pharmakos
Bluelighter
looked through the whole thread, and only two people report having tried MXE + DPT i'll be giving the combo a go soon. glad to hear Help?! enjoyed it, because he and i tend to be pretty similar. 
i'll probably take the MXE orally and then snort the DPT once the MXE starts doing its magic on me.
anyone else have any experience with MXE + DPT?
i'll probably take the MXE orally and then snort the DPT once the MXE starts doing its magic on me.anyone else have any experience with MXE + DPT?
I B Profane
Bluelighter
looked through the whole thread, and only two people report having tried MXE + DPT i'll be giving the combo a go soon. glad to hear Help?! enjoyed it, because he and i tend to be pretty similar.
anyone else have any experience with MXE + DPT?
Not in combination, but I have done each individually, and you sir....have some balls
What doses are you planning on taking? At the right levels this sounds like it could be beautiful, but I would tread lightly with this one. I'm sure I don't have to tell you that DPT ain't nothin to fuck with
pharmakos
Bluelighter
i was thinking 100mg of MXE orally followed by 75mg of DPT snorted 2-3 hours later.
i have a big dissociative tolerance but not too much of a psychedelic tolerance these days.
i have a big dissociative tolerance but not too much of a psychedelic tolerance these days.
I B Profane
Bluelighter
Hmm...my educated guess is that you will trip balls
I've often found that DPT itself has a slightly dissociating element to it, and it can get somewhat spooky at times. I imagine that MXE would make the experience more tranquil, slowed down, and immersive. Let us know how it goes, for the sake of science
FlawedByDesign
Bluelighter
looked through the whole thread, and only two people report having tried MXE + DPT i'll be giving the combo a go soon. glad to hear Help?! enjoyed it, because he and i tend to be pretty similar.
anyone else have any experience with MXE + DPT?
For me DPT+MXE is an absolutely epic combo. It is the only thing that holds a candle to 4-AcO-DMT+MXE(which says a lot). The DPT seemed to cause my mind, brain, body, and soul to vibrate/buzz/hum with euphoria down to its very core. A bit of 4-HO-MET thrown in at the tail end of the trip made for some pretty stellar visuals. Overall it was an insanely pleasurable combination
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vortech
Bluelighter
I realize that there hardly is any difference between the 4-subbed typs and actual psilocybin mushrooms, but in my experience combining mushrooms (no more than 2 grams) with MXE was more soulful/magical/euphoric than the couple experiences I had combined with synthetics (once with 4-aco-dmt and once with 4-ho-met).
pharmakos
Bluelighter
well i went ahead and did that MXE + DPT combo (plus some good cannabis)....
~100-120mg of MXE split into two doses a half hour apart, nice size bowl smoked at t+2h-ish, and then ~70mg of DPT snorted at t+3h-ish. 70mg of DPT may have been a bit much haha. it went okay but could have easily gone downhill at that dose if i was less familiar with intense experiences.
the only way i can describe the experience was that it was as if i was experiencing existence at its most basic level. was pretty much forced to be completely engrossed in the NOW. very alien and bizarre feeling and yet on some level it was a familiar feeling that i've known for eternity. physically it felt pretty safe. mentally all i could manage to do for an hour after snorting that DPT was lay there in bed feeling very, very good, and yet somehow guilty and unsure if i deserved to have as pleasurable existence as i was having. ultimately though i had to accept it -- i was stuck in the experience, for better or for worse.... emphasis on the better tho. :D
next time i do the combo i will definitely lower my DPT dose and possibly lower my MXE dose.
~100-120mg of MXE split into two doses a half hour apart, nice size bowl smoked at t+2h-ish, and then ~70mg of DPT snorted at t+3h-ish. 70mg of DPT may have been a bit much haha. it went okay but could have easily gone downhill at that dose if i was less familiar with intense experiences.
the only way i can describe the experience was that it was as if i was experiencing existence at its most basic level. was pretty much forced to be completely engrossed in the NOW. very alien and bizarre feeling and yet on some level it was a familiar feeling that i've known for eternity. physically it felt pretty safe. mentally all i could manage to do for an hour after snorting that DPT was lay there in bed feeling very, very good, and yet somehow guilty and unsure if i deserved to have as pleasurable existence as i was having. ultimately though i had to accept it -- i was stuck in the experience, for better or for worse.... emphasis on the better tho. :D
next time i do the combo i will definitely lower my DPT dose and possibly lower my MXE dose.
Def glad I stumbled upon this today. I just received mxe and dpt and was wondering about the combo.
Have plenty of psychedelic exp and decent mxe exp. With that being said my mxe tolerance has dropped dramatically in the past month from nootropic use and have abstained from psychedelic(mostly sub tryptamine) use for a month.
I will tread with caution tonight and try 20mg mxe(mholed me last night lol) and then 50mg dpt.
so excited!!
pharmakos
Bluelighter
lol yeah i should emphasize about my dosage -- my dissociative tolerance is pretty big.
100mg MXE leaves me able to talk and walk just fine... barely even impairs my guitar playing anymore. i wish i could mhole off of 20mg!
SONN
Bluelighter
I took a gram of shrooms the other night then snorted probably almost 100mg of MXE. It was wonderful everything was so cloudy and neon in the darkness, then when I finally came down everything looked so saturated and cartoony and I felt super refreshed and inspired.
phatass
Bluelighter
combined it with moxy, i was fine, but my ex defo did some serious dissossiative trippin that night, lost her "logic" and "reason" lie for example running accross the road without looking, mind you she had drank too... towards the end of the trip she was having extremely intense CEV's had to bring her back to reality a couple of times, just to make sure she didn't go too far or get too scared, then she doed off with a couple of xanax, and a noctamide...
deez_utz
Bluelighter
Quick question. I just wanna double check to make sure there won't be any altercations. Yesterday I ate 60mg of adderall mid day, will it be alright to dose MXE tonight?
FlawedByDesign
Bluelighter
You should be fine. Combining the two didn't feel dangerous, just unenjoyable.