• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

How toxic is Mephedrone?

Dresden said:
Mephedrone is more toxic than acetylsalicylic acid, ibuprofen, naproxen sodium, docusonate sodium, sodium bicarbonate, sennosides, diphenhydramine, and dextromethorphan but less toxic than isotretoin, haloperidol, quietiapine, olanzapine, sumatriptan, prednisone, seconal, alpha-methylsufentanil, oxycodone, and thalidomide.

The most common side effect is a reversible headache and occurs half of all users of the drug. Its most serious cosmetic side effect is vasocontriction of the blood vessels of the body's extremities causing them to turn blue temporarily; this side effect occurs in about 15% of users. Idiosyncratic sudden death of the mdma type occurs at about the same rate as seen with that drug (approximately 1 death per several million usages or so).
Click to expand...

Is that your own opinion or have you quoted it from somewhere else?
 
The style is lifted from any monograph from the physcian's desk reference, but since mephedrone is new, I simply wrote my professional opinion. My name is Andrew McNair Pennington. That's who wrote it.
 
The 15 and 50 percent figures appeared in a study floating around out here in cyberspace somewhere. You could find out if u tried.
 
^ totally useless with no scientific basis whatsoever.

monographs are written after the drug is approved after it passes phase 3 trials and also usually incorporate the yellow card information too
 
Last edited:
Permite repetir por favor senor: the 15 and 30 figures came from a published study on the preliminary efffects of mephedrone while the rest of the paragraph is just a connection of words that someone wrote because that's what they thought (def. an 'opinion'). You werent supposed to like it or not like it and even most doctors dont read many pdr monographs so it may have slipped right on past your membranes stylistically there little buddy. Finally the raver kid simply asked me who wrote it so I told him the answer.
 
I agree with vecktor in some areas, and some of the other is true. But the term cascade I have never heard of, although he might be referring to electron transfer. The only thing I can think if which even emulates the term is in photosynthesis and cell respiration. The double CH3 on carbon 1,4 (not alpha) would make it dipolar and have no activity.
 
Dresden said:
Finally the raver kid simply asked me who wrote it so I told him the answer.
Click to expand...

Is that me, the kid? %)

I asked if it was opinion, or whether it had been copied and pasted from somewhere (because that's how it read). So it was your opinion, based on some figures from study.

I have searched for said study and there main reference I can find to those figures is apparently from research at the National Addiction Centre at Kings College, London - quote on this PDF here: http://ussu.info/files/UNISEXMephedrone.pdf

I have since searched the website of Kings College, but cannot find a thing about mephedrone... so I'll take those figures with a pinch of salt.


EDIT: further reading seems to suggest that those figures were from an online poll of 2,222 readers of the clubbing magazine Mixmag. http://news.bbc.co.uk/newsbeat/hi/health/newsid_10000000/newsid_10004300/10004366.stm

Great.
 
opiaddict said:
I agree with vecktor in some areas, and some of the other is true. But the term cascade I have never heard of, although he might be referring to electron transfer. The only thing I can think if which even emulates the term is in photosynthesis and cell respiration. The double CH3 on carbon 1,4 (not alpha) would make it dipolar and have no activity.
Click to expand...

cascade as far as I can determine is nonsense, the person who originated it was a vendor trying to justify his product by clutching at random pseudoscience.
 
I did a g of 4MMC last Wed and now I'm having trouble lifting the fore areas of my feet as well as usual when walking. No causality proved but I wish I hadnt done that now. :X

This is how a lot of new drugs go down the road to perdition in pharmacology and achieve the dreaded black box label.
 
--------------------------------------------------------------------------------

Hello, I am a journalism student and am looking for someone who has had an extreme experience with mephedrone.

I would like to possibly video interview this person, and use all content within my studies.

Anyone willing to help me out would be much appreciated.

Although I am looking for the most extreme of experiences or situations. Such as a trip to a&e, or a week long meph binge.

Thank you
 
Doll said:
--------------------------------------------------------------------------------

Hello, I am a journalism student and am looking for someone who has had an extreme experience with mephedrone.

I would like to possibly video interview this person, and use all content within my studies.

Anyone willing to help me out would be much appreciated.

Although I am looking for the most extreme of experiences or situations. Such as a trip to a&e, or a week long meph binge.

Thank you
Click to expand...
Go try it yourself!
 
Doll said:
--------------------------------------------------------------------------------

Hello, I am a journalism student and am looking for someone who has had an extreme experience with mephedrone.

I would like to possibly video interview this person, and use all content within my studies.

Anyone willing to help me out would be much appreciated.

Although I am looking for the most extreme of experiences or situations. Such as a trip to a&e, or a week long meph binge.

Thank you
Click to expand...
I read this and saw:
-----------
hello I am a journalist and I would like to further sensationalise the mephedrone story without bothering to think or do any background study whatsoever as there is nothing like jumping on a band wagon and we journalists are lazy useless oxygen wasters.

I would like to video interview someone naive, and for this person to prostitute themselves for me and give me material that I can edit twist and butcher so it bears no resemblance to what was actually said
-----------

I think I need to get my eyes checked. :\
 
Shit, me too. Blame mephedrone for this too, of course.
Wouldn't want science to get in the way of a good sensationalist story!
 
vecktor said:
I read this and saw:
-----------
hello I am a journalist and I would like to further sensationalise the mephedrone story without bothering to think or do any background study whatsoever as there is nothing like jumping on a band wagon and we journalists are lazy useless oxygen wasters.

I would like to video interview someone naive, and for this person to prostitute themselves for me and give me material that I can edit twist and butcher so it bears no resemblance to what was actually said
-----------

I think I need to get my eyes checked. :\
Click to expand...

You're the best, mate! Hahaha, thought the exact same thing! =D

No offense meant if you're really a student trying to make it in a journalism career, but how about reporting on more worldly, ambitious and worthwhile stories contained in the study of human rights and politics, etc. rather than becoming a 'journalist' who reports on drugs for the Daily Mail.
 
You could also try researching all aspects of your story rather than just seeking out the most sensational ones. I would consider letting you interview me then were that the case.

The most meph I've done in one run is 3 g's btw. Does that qualify or is it not extreme enough? Even then, the effects were not nearly as horrifying as some of the less memorable shroom or lsd trips I've had.

Again, tho, comparing pea's to indoles is a non-comparison imo, like comparing apples to oranges, really.
 
MeDieViL said:
How would viagra work to counteract the vasoconstriction?
Click to expand...

Because it basically does the opposite of vasoconstriction, by expanding your blood vessels to improve blood flow to extremities.

My doctor has prescribes it to me to treat Reynaud's Phenominon that I occasionally get attacks of. If I take 5mg of it when I'm having an attack the vasoconstriction goes away.

Not sure how it would affect males, but AFAIK a dose for ED is more like 50mg.
 
vecktor said:
I read this and saw:
-----------
hello I am a journalist and I would like to further sensationalise the mephedrone story without bothering to think or do any background study whatsoever as there is nothing like jumping on a band wagon and we journalists are lazy useless oxygen wasters.

I would like to video interview someone naive, and for this person to prostitute themselves for me and give me material that I can edit twist and butcher so it bears no resemblance to what was actually said
-----------

I think I need to get my eyes checked. :\
Click to expand...

epic lol!
 
You must log in or register to reply here.
Top