The funniest thing that I have ever witnessed (also the scariest, I might add) is when a friend of mine dosed some 25-I and found himself in a loop.
It started off pretty funny when he threw up a little bit on his shirt and we told him to change it; well, he kept walking upstairs to get a shirt and then back downstairs... without a clean shirt! We were all outside smoking and saying to him, "Alex! Where's your shirt, dude?" and he'd say, "oh, right," then go back upstairs only to repeat this whole thing over again. I swear he must have done it a million times.
Then, he started to repeat the same phrases over and over again. He would keep asking in a very child-like way, "What should we do, guys?" And then he'd say (as a question), "Should we don't smoke?" and "Let's everybody don't be a cigarette!" You almost need to say these things out loud to realize how funny they are lol (We kept going outside to smoke, and he didn't like it, so I think that was part of it.)
But then things just hit the fucking fan, man. He could not say anything else but the same phrases over and over again, and those phrases were, for the most part: "asian girl!" and "big tits!" and "everybody don't be a cigarette!" He just rolled around in bed and would put these phrases together, like he was trying to find the right combination of phrases. He'd say... "asian girl, big tits, everybody don't be a cigarette!" then he'd think about it and say, "big tits, asian girl? don't be a cigarette... asian girl.... big tits!" It was ridiculous, and we were rolling on the floor laughing.
Then, six hours later when we realized that he wasn't coming out of it (no, really, six hours), we kind of freaked out. No, we didn't call the ambulance or anything like that. We were novice trippers, for sure, but we knew enough not to do that. Anyway, we stayed the night with him to make sure he came around, and, eventually, he fell asleep and then woke up and was perfectly fine.
But we still laugh about it, man. "asian girl! big tits!" And the best part is that this kid does not do drugs very often (that's part of the reason why he wanted so many people there with him, people who are a little more experienced); he's very quiet and reserved, and, for whatever reason, he had this idea that if he tripped, he would come to some revelation over why his girlfriend of five years left him. In other words, he was looking for some great revelation, a religious experience of sorts, and "big tits" is not something that he would say in front of anyone, not his friends and certainly not in front of the few acquaintances that were there at his apartment (friends of friends).
We joke that he did have that revelation and that he did come to some great understanding, but that his brain fried at the very moment when he had it, and so, like a skipping record, all we know is that it had something to do with an asian girl with big tits and definitely, definitely not smoking or "being a cigarette."