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Comedowns, Serotonin Syndrome and MDMA abuse (plus problems after use)

Feeling horrible............

Hello! I made a post about anxiety caused by MDMA a couple weeks ago. I pretty much recovered from the MDMA after 2 weeks, but all of a sudden I have sympytoms of LPR (Laryngopharyngeal Reflux Disease), constant mucus in throat, heartburn, chest pain, nausea, and some of the anxiety returned! Could this be a cause of MDMA or anxiety??

Note: I never had LPR symptoms before or anxiety.
 
Honestly, you need to see a doctor if you want a meaningful answer to this question.
 
Very informative. Thanks a lot. I believe I do have sleep apnea so I'll look into that. Maybe a cpap or something.
 
Do you find that when you sleep on your side one half of your nose closes off your do you have problems breathing through your nose at night? I used to have sleep apnea because I couldn't breathe through my nose so I snored through my mouth instead, a septoplasty that fixed my deviated septum actually cured my sleep apnea.

Try to get a sleep study done. Sleep apnea is actually very common, and does indeed strike the skinny like myself.
 
Your saying you took 3 pill plus a gram of mdma on top of the...and you are wondering why you feel fucked after?

Natural selection missed another one
 
What kind of fucked up did your friends say you were? Knocked out or partying? Could've easily been some sort of date rape pill so I'd be careful there haha. Other than that I'm not sure what it could be, sorry dude. Maybe you got more drunk than you thought
 
Too much drugs.

Stop taking drugs, get plenty of sleep, exercise regularly, and eat healthy. Eventually, you'll feel better.
 
I would also get a testkit, no way what you took was pure MDMA. That would have without much doubt landed you in the hospital if that was pure stuff. Or are you rolling every weekend and have built up a monster tolerance?
 
Could be because of multiple reasons. MDMA + alcohol is a combination that's very much capable of causing complete blackouts. Even MDMA on its own, when taken in insane doses, can cause (pretty scary) blackouts. And yes, it could also be that you took something else entirely. No way of knowing without testing :)
 
You filling your mind with any possible disease, illness, or disorder that could be going wrong could also result in a shitload of anxiety.

Go back to the doctor and get checked out or at least stop trying to self-diagnose, it'll only cause you more anxiety and drive you mad.
 
Dusk said:
You filling your mind with any possible disease, illness, or disorder that could be going wrong could also result in a shitload of anxiety.

Go back to the doctor and get checked out or at least stop trying to self-diagnose, it'll only cause you more anxiety and drive you mad.
Click to expand...

QFT. I did the same about 2 years ago. I freaked myself out because I thought I matched all of the symptoms of a liver disease, and the doc flat out thought I was an idiot because I checked out completely fine.

Going to the doc is absolutely paramount if you truly care about your health. They go through grueling medical school, suffer "medstudentitis" and are literally handpicked out of thousands of qualified students just to help poor saps like us. They know their shit better than anyone that does less than this.

For myself, I had a hard time caring about my own health and didn't shit about it constantly. But I'm at that age where I can't be doing that anymore, so now I'm relegating myself into being super proactive about it. I'm even gonna take a trip to the dentist soon, which I freakin' hate, because I was traumatized after getting all four of wisdom teeth pulled out wide awake. That was nothing short of a nightmare.
 
Doctor diagnosed me with aCid reflux and now im on protonix.. hopefully I get better thanks guys
 
In the meantime before you get a chance to get to a doctor you can try an over the counter medication like Zantac that will help with the acid.

There are many causes of reflux but the only real possible way that MDMA could cause reflux is by causing sleep apnea, (a study showed a correlation between MDMA use and sleep apnea). However there are many other possible causes of GERD, like infection with H. pylori. But if it's within your means I would try to get a sleep study done to check for sleep apnea, it's relatively common even in the skinny population so it's a good thing to rule out anyways if you're having issues.
 
Addiction itself works on a cellular level by a mechanism akin to "reverse tolerance", this happens through ultimately genetic means, something called DeltaFosB that is strongly implicated in addiction. When DeltaFosB is expressed after drug use your brain will actually become more receptive to a drug. At least some of the positive effects related to dopamine in a part of the brain known as the pleasure center called the nucleus accumbens.

There is a similar process known as long term potentiation that basically means when you use a certain cellular pathway (stimulating it with drugs) that pathway becomes stronger and stronger.

For whatever reason your brain might have strong long term potentiation abilities. This could be due to a lot of the receptor called NMDA that promotes long term potentiation, DXM works on NMDA. If you had over expressed NMDA then it makes sense you would not gain tolerance to DXM very quickly (there would be a lot of brain cells for DXM to work on) and it would explain why you never gained tolerance to other drugs very quickly (NMDA is anti-tolerance effectively).
 
Terrible MDMA comedown and my life since

Hello my name is Gabriel and I'm 19, I just found this website as I have been dealing with a pretty severe molly comedown.

It's been 2 months and 23 days since I took it so it was on halloween, I was feeling anxious that day as I was dealing with some personal stuff in my life but as usual I got drunk and forgot about all of that and a friend of mine had bought a half or full gram of molly or at least I think it was and me and a couple of friends started doing lines and I want to say I did about 3 of them so maybe .2 or so.

as a prequel I've done my fair share of drugs before I've done a lot of coke and ecstasy about 25 times but never too much. But I hadn't done any MDMA for months before although I did do some coke the weekend before.

So the high was normal it hit really quick because we snorted it and it wasn't too much and I wasn't even rolling that hard and I was about up for about 6 hours on it then passed out by drinking some more and the next day I woke up and felt pretty down the normal stuff you feel after a roll I was a little out of it and fell asleep pretty normally but then suddenly in the middle of night I woke up and felt like I was completely losing my mind.

I couldn't have one normal thought it's as if my mind was racing at a million miles per hour and I felt extremely uncomfortable and depressed and paraniod and suicidal I didn't know what was happening to me I was completely freaking out and my anxieties were taking over, that night was able to fall asleep for an hour or two then wake up freak out and fall back asleep again.

The next day was just as bad and it was as if every hour or two I would have an extreme panic attack my heart wouldn't race but I felt like I needed to leave my apartment and when I started to feel like that I wanted to jump off of a cliff and end it it was so severe, over the next few days it started to get better I got my hands on some xanax and it helped and about after a week I was starting to feel somewhat okay again but I couldn't stop thinking about how scared I was and how paranoid and depressed I was I seriously thought I was turning into a crazy person.

And after about a week a decided I could try and drink again and it helped but I would wake up feeling very anxious again and about 2 weeks after my comedown I felt like I could hardly breath and that caused me a lot of anxiety and since then I have felt anxious pretty much everyday and every now and then suicidal and I'm so scared that I have permanently messed up my brain and that I will never be the same again and I just wanted to reach out to this feed and see if anyone has had any of the same kind of experience. I have done coke a few times since then and that has been a terrible idea I felt even more suicidal and depressed about my life and I feel like I will never get better and I fear that has only slowed my progress

It's hard to get through everyday without thinking about the experience and it's like a terrible circle I'll feel anxious about something then sum it up to me doing the molly and I'll freakout and think that I fucked myself over forever and I hate feeling this way I wake up feeling so scared and depressed. And throughout the day i's hard for me to do anything without starting to feel anxious and worried that I ruined my brain.

I have just started to see a psychologist and a psychiatrist and she put me on busiprone and that only made me spacey and even more depressed and last night was very dark and I was feeling suicidal.

I wanted to get in contact with people who are going through what I am and if they think anti depressants are a good idea because I definitely think they might be beneficial and how much longer I will be feeling this way because it's absolute torture and I want some reassurance that I'm not going to fee like this forever because I get so scared and stuck in my own head. But since I am feeling suicidal I don't want to feel like that ever but the thoughts are so convincing that it's easier then going through what I am.

I am never going to do a hard drug again and I'm going to abstain from alcohol as much as I can. If anyone can respond I would greatly appreciate it and if you have any questions and want me to go into detail on how I'm feeling feel free to ask thank you.
 
I'm gonna start off by saying the basic things. Always and I mean ALWAYS test your MDMA before you take it. Don't go on someone else's word. I've made that mistake once and ever since if I've done something like this I tested it. I once help onto a gram for 2 weeks until I could order a regent test. Its a lot safer this way and makes me more comfortable whilst rolling.

Secondly eye-balling powdered or cyrstaline drugs is a horrible idea. I could be thinking your taking .2 when really its .5 or more.

You won't feel this way forever but you have to treat your body respectfully and healthy-ly during the recovery. Excess drinking isn't really advised. I'm glad you've seeken help through professionals and experienced individuals.

I went through a terrible comedown last year that lasted around a month and a half to 2 months. Longest couple months of my life but I ate well and getting a lot of exercise helps. So does staying hydrated.

The main thing to remember is that with time and a smart recovery process you will come back. Learn from these experiences too. I hope you get better through the next month or couple of months.
 
^You should listen to what this guy is saying, especially about the eyeballing tidbit. It doesn't matter if the substance is considered safe or not, because that is an incredibly bad idea and habit (if you make it one). There are many substances that are only safe IF you control the amount of the dose. Not just illegal substances, but you can even die from eating too many zinc tablets too.

Just be wary of what you're putting into your body. You only have one life, so it's not the kind of mistake that you can take back.
 
Extremely bad comedown after every use of mdma

I'll try to get this across as simple but detailed as I can.

Basically the next 1-2 days after using e I suffer with an extremely terrible feeling like a flu sort of, I can't eat, my face is red and hot, I have no energy, I can't sleep, a terrible feeling in my mouth, I feel weak, I have that fuzzy feeling in my head like you get when you're really sick, almost no saliva even after drinking endless amounts of water and other fluids, only I finally get to sleep after hours of it being worn off I'm usually woken up a few hours later to a voice in my head that won't stop talking and I'm unable to sleep again.

I've been using e for awhile but this puts me off for long periods at a time, when I first started I had no effects the next day,
I know for certain they're not bad pills because my friends feel fine the next day.

The other week I only ate one just to see if I'd have the same feeing the next day, I didn't even feel the pill but the next day it was the exact same feeling, I tried going to sweat it out at a steam room and sauna whilst hydrating for over an hour but there was no change.

I hydrate myself well when I roll and eat beforehand, I eat healthy and am always hydrated during my normal days.

I have absolutely no idea why this happens but all I want is an answer on how to stop this and feel normal like everyone else does the next day !
 
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