Its safe on your body ime just be prepared to trip pretty hard. I like to eat them all at once or split my mushroom dose in 2 and eat half with my 2c-x compound and eat the rest of the fungus when i want to eat more which is usually pretty quickly. I have only had the chance to do cubensis+2c-e but 2c-b isn't far from that. Be careful though do not overdose it, i did it once and it wasn't a pleasant 8-10 hours and i only had 1 gram of strong cubes that wore off after 4 hours then i was in 2c-e mode for a good while, i had around 30-40mgs of 2ce which i thought was 17-20mgs, i fucked up it was my fault.
-MXE and mushrooms is intense to, only did once but i have had the chance to try mxe+4-aco-dmt F. a handful of times. I like Actylpsilocin+MXE a lot more though, i figured the mxe would comfort me during a mushroom trip but it did the exact opposite i was very uncomfortable for for hours.
-Fungus+ 20mgs of Actylpsilocin is also really nice, although i only ate a gram it was still intense. very colorful visuals, headspace/body high was nice to, i laughed for the majority of the trip. This combo is on my to do list again higher doses of both will be consumed along with hash oil this time, wanting to see if i can take it further this time.
Happy tripping! enjoy yourself, i don't have access to 2c-b at the moment or else i would be seeing how this combo is for myself lol. Also if you don't want to eat mushrooms while your already tripping you could cut your mushrooms up with scissors and shove them into capsules if you have access to capsules.