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Codeine Extraction

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I have another question. I have some loratidine in my medicine cabinet. Will that work instead of the desloratidine?
 
Yep. The "-des" designation is just specifying the stereochemistry of the compound in it (it contains just one stereoisomer). The stuff you have is racemic loratadine (it contains both stereoisomers). It'll work just fine :) .
 
Thanks dude. You're ace! The list of CYP2D6 inducers is very small so I'm thrilled to have found something on that list that's easy to obtain.
 
Yeah, just be careful you don't overdo the alcohol if you're sensitive. I accidentally did that the otherday; the alcohol made my stomach a little upset and after I threw down the codeine began to vomit...luckily I caught it in my mouth and *shudders* swallowed it back down again, lol :)
 
Oh, and I just found this study which indicates that echinacea has a mild inhibitory effect on CYP3A4 and little effect on CYP2D6, whilst Ginko biloba has a mild-to-moderate inhibitory effect on 3A4 and little effect on CYP2D6.
 
Tortoise reporting:

T-1.5hrs: Injested loratidine, St John's Wort and Echinacea
T=0hrs: Inhested 340mg codeine
T+40mins: Very, very underwhelmed
T+1.0 hour: So underwhelmed that I ingested poppyseed tea made from 240g of poppyseeds.
T+3.5hours: Feeling nice but wanna feel nicer so had some more poppyseed tea
T+4.5hours to 12hours: Feeling very nice

Conclusion: Not convinced of efficacy of st john's wort, loratidine and echinacea to potentiate codeine. It almost seemed to inhibit the effects of codeine but I will try again in near future just to be certain.
 
Cold Water Extraction on P15's

[EDIT: Threads merged. hoptis]

I tried a cold water extraction on 7 x Panadeine 15's ( 15mg codeine in each caplet). Does anyone know if I should use 1 or 2 coffee filters to remove the paracetamol ? I certainly don't want to drink 3.5g of paracetamol !! The white powder left over in the filter - is that the paracetamol or some other filler ?
Thanks
Frank
 
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Someone will correct me if I'm mistaken here but apparently coffee filters are bad for CWEs as they are designed to let small particles through. You are better off to use a piece of an old t-shirt. That's what I've read anyway.
 
I use 1 filter when doing Panadeine 15's, the solution should be pretty clear. The powder caught in the filter should be the paracetamol.
 
It really depends, i usually get a clear solution with one filter, i use two if im in a hurry and want to squeeze it incase the inside one bursts, and i get a clear solution.. Thats with any codeine/paracetamol tablet.
 
How many caplets do you suggest to get a good buzz ? I felt OK with the 7 x CWE P15's, however it didn't feel as good has having 3 x Panadeine Forte's.
 
Try getting Chemist's Own Pain Tablets, they dissolve real quick, easy to filter (I use a shirt) and they are dirt cheap (usually).

One pack = 240mg, gets me relaxed, two packs = 480mg and will get me buzzing pretty good.

I love the codeine, I usually use grapefruit juice to help make it last longer, and recently have been using St. John's Wort and alcohol to help boost it a bit.
 
hmmm good idea to try the Chemist's own, since the P15's are relatively expensive for a box of 12. So I gather the paracetamol solids are easy to filter if they can be filtered with cloth ?
 
Frank.

I cant give you the proper URL at the moment because I am at work and I go through a proxy. do a search in this forum for a thread called 'codeine extraction'. Read towards my post about using cloth.
 
Well, the jury is kind of out on the filtering with cloth. Some people say it's dangerous, others say it's safe. One guy said he let everything evaporate to a powder after doing a filter with cloth, and got about 1 gram or under of solids. If you subtract 240mgs of codeine, that would be around 760mgs of paracetamol; perfectly safe if you're not using everyday.

I filter with an old work shirt made out of polyester cotton. I always get a cloudy solution, which I assume is binders and fillers, and I've been doing this for well over a year without any liver problems. I'd say it's pretty safe.
 
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i would rather bang 100mg of PMA at once in 10 units than use a clopth for cold water extractions.. shit whenever i do it i make sure its nearly clear as tap water. takes hours.. i probably lose codeine but i make up for it by putting more pills in... fuck Paracetamol overdose.
 
Well, the only way to find out if I'm doing damage is to go get liver tests done...but I haven't had any symptoms of liver damage in the past year that I've used, and that includes a period of 6 months involving almost constant abuse. If that didn't shut down my liver, I'm pretty sure I'll be cool with codeine once a week + some paracetamol.
 
All my CWEs take less than 15 minutes, i get a clear solution every time and i use a coffee filter.. fuck using dirty rags or t-shirts with porous weaves.. it lets more particles thru
 
Dirty rags lol.

Using a cloth is a good way to get rid of the majority of paracetamol. Using a cloth to filter it first, then putting it through coffee filters will produce a safe solution.
 
i hate waiting for it to drip.. one second passes.. drip./. one second passes eetc.... then it starsty dripping every 5 seconds.. then it starts dfrying on the sides of the coffee filter... i dont understand how people do 15 min extractions
 
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