Yup Im in the same boat as you, along with quite a few other people. Always manage to get severe nausea with 2c-e. I have no problem with high doses of 2c-I, or low to medium doses of 2c-t-2. The first 3 times I tried 2c-e I kept it down, but since then I have always thrown up at least 3 seperate times each time I took it, regardless of dose and I even tried the the popular methods of combating 2c-e nausea (benadryl, drinking your dose spaced out over in hour) and neither of those gave me much relief, but they did help some.
With 2c-e, I feel like the big question is "is the trip worth the come-up?"
And for me, the answer is maybe one day, but for now the side effects have forced me to shelve it. Also 2c-p and 2c-d are very close relatives of 2c-e, and 2c-d is regarded as the tamest of them all so you might have some luck there.