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  • EADD Moderators: Pissed_and_messed | Shinji Ikari

The GHB/GBL Addiction & Withdrawal Thread

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GHB vs GBL WD's

Hi all i just joined after reading the GHB/GBL threads on here. Hopefully my
experience wil be useful.

I first sampled GHB in 2004 after reading about it on the net. I was concerned about my own drinking and saw reports that it wasn't addictive and helped reduce the craving for alcohol.

I purchased some GBL, did the conversion to GHB, tried it and loved it. It did seem the wonder drug everyone described, completely removed my urge to drink excessively, and actually made me feel euphoric and more sociable, not to mention the sex.

After a while i fell into the same trap as many others, taking larger and more frequent doses, eventually reaching 24/7 dosing of approx 3-3.5g every 60-90 mins. I found more and more excuses in everyday life to use it. By definition the more wrecked you get on it the less you care how much you're taking..you don't even notice dependance developing.

Skipping forward about 2 months of 24/7 abuse I lost my job, and lost my 'drive to suceed' i spose you could say. By that point the euphoric effects of GHB had long gone and I was just taking doses to feel normal and keep the sweats / shakes away. Days and weeks flew by like hours and I got lazy and started taking raw GBL instead of getting off my arse to do the conversion.

From there it only got worse due to the more rapid 'up+down' of GBL's effects, my doses got up to around 3-3.5ml every 60mins. Grabbing maybe 2 hrs sleep a night. You always mean to start tapering down your dose but something always 'comes up' that day and you take a little top up to deal with it. It happens every day when you get that far in.

This continued for approximately a further 18months until I ran out of money, couldn't buy G and had to sort myself out. Towards the end of the binge, other health problems were beginning to show as a result of the GBL use, fluid retention, numbness in my hands and regular muscle cramps from, as it turned out, metabolic acidosis.


Please no-one be offended by this, but I do need to clear some points up, which others have posted incorrectly on..

GHB/GBL works on GABA-b receptors.. yes.
GABA-b is an inhibitory neurotransmitter and regulates the brain by slowing electrical activity.

GHB also works on a GHB receptor in the brain...YES! there is one, and it also increases HGH levels in the blood, which acts like a natural steroid.

It's activity at GHB receptors combined with the increased HgH has a stimulant type effect (the initial euphoria you get on G), while the sedating effect is brought about by G's action on the GABA-b receptor. The typical upper+downer combo which makes us all act like such dicks while under the influence of it.


As you can imagine if you get a tolerance to a chemical / neurotransmitter, your receptors for that neurotransmitter adjust to the higher / lower activity level they now see. It's called up/down regulation.

If you suddenly stop G use you're going to feel weak and depressed from the downregulared GHB+HgH receptors. You will also be anxious from the upregulation of GABAb receptors, with not enough GABA to keep things calm.

The horrible initial comedown you get off G is caused by the 2 neurotransmitters i just mentioned. - GABA, and HgH. Dopamine has no involvement in this comedown feeling..

People incorrectly say it's an excess of Dopamine - a 'rebound' effect. Nope a sudden rush of dopamine is actually very pleasant, people pay £50/g for it in the form of the Dopamine agonist Cocaine.

GHB withdrawal does also have the effects the some posters already stated.. on the cholinergic system though. This is brought on indirectly by the effects on the GHB and GABA receptors however, not Dopamine 'rebound' or HgH. Cholinergic effects will vary...hot flushes, high BP, tachycardia, sweating.


Dopamine DOES play a part though...

Here's how my witdrawal went:
T0:00 Last dose consumed.

+1hr anxiety and heart rate steadily increasing, sweating, tremor beginning in hands. Consumed an insane quantity of Propranolol to keep heart rate under 130bpm (>800mg - don't do this, ever! Consult a doctor if you get tachy)

<= Day 8...Tremor, sweating and heartrate slowly decreasing, anxiety persists. Alcohol taper (started @ 20 units/day) used as GP refuses to prescribe benzo's of any quantity.

Foolishly think i'm through the worst.

Day 8> Holy shit, NOW we have Dopamine kickback..full 10/10 anxiety, general discomfort, severe tremor / involuntary movements, fully formed delusions, auditory + visual hallucinations, nightmares. Classic DT's by all accounts.

Brief hospital admission after vomiting so much i recieved a small tear to my throat = lots of blood.

Day 14 > I was finally feeling better. Lethargic and mildly anxious mental state remained for 5 months.

I agree fully that the severity of withdrawals will depend on how much, often and long you've been taking G for.

And from my own experience I'd also agree that every time you have WD's, they'll be worse the next time. It's the same as the 'kindling' theory about alcoholic WD's in the US.


I would say to anyone considering taking GHB/GBL, 1st never get into 24/7 dosing (easier said than done sometimes - it creeps up on you).

Dose taper withdrawal from GHB, although still unpleasant, is nothing compared to the horror of recovering from long term GBL abuse.


If you must get the G buzz....use GHB not GBL. It's stupidly easy to do the conversion... take the actual intended drug, don't drink the ingredients. If you want a sandwich do you use a slice of baked bread, or just eat a raw egg, some flower, and yeast?

Finally, never think you're doing well by taking G cos you've stopped drinking. Cross tolerance between Alcohol and GHB/GBL exists because both affect the same neurotransmitter - GABA, and both chemicals are broken down by the same liver enzyme. You haven't stopped drinking, you've just changed to a stronger drink.

Don't believe me? stop taking G for a day and see how much you have to drink before you feel it..

^^
Annyyyway that's mainly aimed at the people who still want to take up the 'sport', i'm not really preaching at anyone, if you're happy doing what you're doing, keep doing it;)

Nigel
 
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Finally, never think you're doing well by taking G cos you've stopped drinking. Cross tolerance between Alcohol and GHB/GBL exists because both affect the same neurotransmitter - GABA, and both chemicals are broken down by the same liver enzyme. You haven't stopped drinking, you've just changed to a stronger drink.

Don't believe me? stop taking G for a day and see how much you have to drink before you feel it..
I'll just start with this bit, for now. Alcohol works on the GABA-A receptor. G works on the GABA-B receptor. There is no cross tolerance between the two. You simply have to drink more alcohol to 'feel' it, as it is working on a totally different receptor, and it's crap at stopping rebounds and withdrawals from G. You can take plenty of GABA-A agonists and still suffer the effects of abusing a GABA-B agonist, with hardly any relief.
 
I'll just start with this bit, for now. Alcohol works on the GABA-A receptor. G works on the GABA-B receptor. There is no cross tolerance between the two. You simply have to drink more alcohol to 'feel' it, as it is working on a totally different receptor, and it's crap at stopping rebounds and withdrawals from G. You can take plenty of GABA-A agonists and still suffer the effects of abusing a GABA-B agonist, with hardly any relief.

I can partially agree with that. It's generally accepted though that Benzodiazepines are a useful treatment for G withdrawal, although usually very large doses are needed.

GABAa agonists (benzo + alcohol) all have some affinity for the GABAb receptor, the reason the required effective dose is so high is their affinity for it is little compared to that for GABAa, hence large dose required before adequate binding is achieved.

The brain can't really distinguish one GABA receptor from another in the way you 'feel' it. For this very reason there is a cross-tolerance between agonists of either receptor.

Baclofen would be generally accepted* as the 1st line WD treatment as has been mentioned previously. This isn't known by many GP's so if you get stuck, you're gonna have a rough ride. Ideal would be antipsychotic + Baclofen titration followed by taper, but that IS NOT going to happen.

I wasn't recommending what I did as a useful withdrawal method, I was just stating what happened. After reading all 3 GBL threads I felt there were an alarming number of people who 1st asked 'how do i take it' etc, then ended up posting they're stuck on 24/7.

As a harm reduction site I thought i'd give an account of harm. But I knew it would offend some.

I do know a bit about it mate, I was stuck in that rut for a long time. The main thing i'm trying to get across is don't take GBL - it's not a drug, it's a solvent. It was never intended for human consumption.

Yes it gets converted to GHB by your body, but with most of us knowing how strong (yet simple) a chemical is required to convert GBL to GHB...do you want your body taking that workload?

GHB is a drug and was intended for human consumption.

That's all.

cheers.


* http://w*w.ncbi.nlm.nih.gov/pmc/articles/PMC2630388/
(not sure if external live links allowed)
 
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Water's a solvent and so is alcohol - being a solvent isn't necessarily a bad thing ;)

Interesting posts. And kinda scary too. I've yet to experience any withdrawals even after very prolonged periods of 24/7 usage but am not stupid enough to be complacent about it. I do get the rapid heart rate, sweating and general unease if I stop but it seems to be gone once I've slept - and I rarely have more trouble sleeping than usual when I stop. It also doesn't seem to return for the following days.

The worrying part for me is the delayed reaction - the sudden ramping up of effects after a week of false security. I'm not sure how long the longest gap between bottles has been but probably don't make it far beyond a week often. It's certainly given me something to think about but withdrawals from this stuff seem to vary a lot between individuals. Intriguing... if a lil worrying :\

Also, welcome to BL and EADD :)
 
Baclofen would be generally accepted* as the 1st line WD treatment
Baclofen and phenibut are by far the best things to stop withdrawals dead. A low dose of codeine, or ketamine, stops the dips in mood.
 
GBL Withdrawal

I've just come out of hospital after my 3rd admission after being found in a coma through too much G.

I was doing it from 1sept - 27 Oct. I started at 2ml, but had to redose 3hrs later with 3ml to keep the buzz going.

I went into 24/7 use almost immediately as the comedownw as shite even in the beginning, and as I was off work, I could use it any time I wanted. A week in, and I was doing 5ml on waking up (after two hours max sleep), then 3ml every two hours during the day.

This went on until I got greedy (being an addictive kinda guy, you could say) and started taking 4ml every two hours, and just 8ml to try to force me to sleep.

I wanted to stop after 3 weeks, because the pleasurable sensations were no longer there, and I was takin more and more to chase them.

Eventually, I tried to withdraw, and got some benzos and sleeping pills. BUT, being the addict (idiot) that I am, I started taking them together!!

Cue withdrawing cold turkey after two months 24/7. After a day or so, (first day was ok, so I thought this would be easy) I started seeing people in the flat, worms under my skin, colonies of ants walking across the wall, and an army of people hiding in the trees shooting a porno film - they had the entire street blocked off! I was so out of it, I called the fucking police twice8o and pointed at the people outside the flat window (which is on the third floor)! Man, that was a nightmare. I was chasing big spiders all over the flat, and the cat kept attacking me (she actually did!).

4 days of hallucinations I KNEW WERE REAL, scared the fuck out of me, especially when I nodded off after 3 days without sleep, and had the most horrific nitemare ever. When I was told by my wife that there wasn't someone actually going to blow my brains out and disembowel my family, I screamed and dived onto the floor (like you do!).

Still, it didn't stop me ordering more. And after being off it for a week during which I took baclofen, another bottle arrived. That was the first of a few ambulance trips, the last one of which saw me having cpr, and being basically dead - no pulse and no breathing. Thankfully, some family present called the NHS for the ambulance and they spent 5 mins talking them through trying to keep me alive (cpr, rolling over on side etc). When I would pass out into a coma like this, it was always instant without warning, and I broke my nose and cut up face quite badly, fucked ankle etc etc.

I wouldn't advise anyone to use this shite. I've had an opiate addiction before and the WD from that was nothing compared to this stuff. Only those that can say "no" after taking a substance should use it. I don't fall into that category as when I drink etc (alkie for 2 yrs as well - meaning for life) I can't stop.

HTH
 
Yeah, One thing i've noticed from my reading (and also reflecting on my own personality), is that those of us that end up on 24/7 are people who've previously had alcohol issues or have self medicated using alcohol / benzos for anxiety.

IMO people who fit into either / both of these categories should steer clear of GHB and GBL.

I fear now the ban is imminent, a lot of users will find themselves in deep trouble.

To anyone currently dependant on either chem, i'd suggest you seek help or otherwise take action NOW, don't wait till its too late.

Good luck everyone :)

Thanks, Nigel.
 
Didn't think dosing once every day/ever 2 days in the evening around 8/9pm would really make me suffer any withdrawls but I just can't seem to sleep... :( Was up till stupid hour last night turning over and over
 
GBL and sleep

Didn't think dosing once every day/ever 2 days in the evening around 8/9pm would really make me suffer any withdrawls but I just can't seem to sleep... :( Was up till stupid hour last night turning over and over

I've spent a lot of time reading everything I can find on gbl on the net. One medical paper was from a psychiatrist who detailed a bodybuilder showing up at the hospital in a bit of a state. He'd been using the then legal blue tabs with ghb in them for around 12 months (not certain on time scale, but it was thereabouts). He had chronic anxiety which he couldn't understand and his main problem was that he just couldn't seem to sleep. He took his pill at night, like he was supposed to, to give him a deep sleep and release HGH. When he stopped taking the tabs, after stories started emerging about their saftey, his problems began. The psychiatrist treated him with very high doses of benzos and he was an in patient for 7 days.
 
GBL and addictive personality types

Yeah, One thing i've noticed from my reading (and also reflecting on my own personality), is that those of us that end up on 24/7 are people who've previously had alcohol issues or have self medicated using alcohol / benzos for anxiety.

IMO people who fit into either / both of these categories should steer clear of GHB and GBL.

I fear now the ban is imminent, a lot of users will find themselves in deep trouble.

To anyone currently dependant on either chem, i'd suggest you seek help or otherwise take action NOW, don't wait till its too late.

Good luck everyone :)

Thanks, Nigel.

Good point Nigel.

In full agreement. I was on effexor and propranolol for anxiety/depression which managed to keep it at a fairly low level. I've since got myself some other non medical approaches, which I'm using.

What I found, was that the comedown from gbl with its incumbent anxiety, sent my already anxious brain into anxiety meltdown. Hence the desperation to redose immediately to relieve it.

Again, with addictive people, we can never let enough be enough, but ride the rollercoaster until it stops dead. I had thankfully a good amount of hospital time so I could clean up from gbl, but on the last occasion, I was released at 4, got home and poured straight from the bottle into some coke, and was in the ICU at 1730!8o

That has to be high on the Darwin Stupidity Charts somewhere, I'm sure.

I agree with you that those on G need to get off it whilst they still can, otherwise the hospitals will be full of people running from big rabbits with samurai swords :)

My anxiety levels are still high, but reducing, and sleep is starting to approach a decent enough level so I'm not wrecked all the time.

What an experience. The last two months FLEW past, and i can't remember that much about them, as I was simply sitting in front of the pc redosing until it got daylight at times, then a frenzied fit of sleep, then the cycle would start all over again.
 
I've spent a lot of time reading everything I can find on gbl on the net. One medical paper was from a psychiatrist who detailed a bodybuilder showing up at the hospital in a bit of a state. He'd been using the then legal blue tabs with ghb in them for around 12 months (not certain on time scale, but it was thereabouts). He had chronic anxiety which he couldn't understand and his main problem was that he just couldn't seem to sleep. He took his pill at night, like he was supposed to, to give him a deep sleep and release HGH. When he stopped taking the tabs, after stories started emerging about their saftey, his problems began. The psychiatrist treated him with very high doses of benzos and he was an in patient for 7 days.

Well yeah, I could REALLY do with some benzos at the moment. Reckon the doctor would prescribe me anything if I went and explained my situation? Was thinking probably not..
 
In the doses you are taking, you are unlikely to encounter any issues. Just watch that it doesn't creep up. Some people (people with anxiety, depression, etc.) seem to be more prone to addiction than other people. The first withdrawal is nothing, but as time goes on, they get VERY severe. Treat it with respect, and it will treat you with respect. Abuse it, and....well, you've read this thread.

Eclipse: Order some phenibut. It comes the next day, and it will get you off G with the first dose.
 
Eclipse: Order some phenibut. It comes the next day, and it will get you off G with the first dose.

Thanks for recommending that, but I really don't want to replace one thing with another.
"Phenibut can have unpleasant dose-dependent withdrawal symptoms. Withdrawal symptoms can include acute anxiety and insomnia that can last for up to two weeks afterwards. Withdrawal symptoms, however, are almost always associated with cessation after prolonged usage." I got from wiki-ing it.

I've gone 5 days without geeb now and sleep is returning to normal, was quite harsh but cold turkey style worked for me.
 
Oh, right. I thought you were in a "fuck, I've got 10mls left" situation. Five days is a good amount of time to recover. :)
 
Ahhh nah it wasn't quite that bad, but I could see it getting that way which is the exact reason I stopped. Going to save it for the special occasions now :)
 
Converting to ghb

Just as a footnote, I had read about the conversion on the drugs forum, but they used the chemical name of the stuff, naoh or summat, and that threw me, not being chemically minded (8o), with lab names at least.

If I'd known it was simple caustic soda that you can get in any supermarket, I'd have done the gbl/ghb conversion, as GHB is actually branded as a drug for narcolepsy (sleeping disorder) as lyrica, and has been used for years by folk without any problems. In small doses at night time.

After almost two weeks without any G, I'm still feeling very depressed and anxious, and got myself some otc codeine yesterday as I'd had enough of it and needed a mood changer. I've started walking a few miles yesterday, to try and stimulate some dopamine naturally.

I might get some more gbl but in very small amounts this time, and do the conversion properly. Last orders were for 3 half litres and one litre. My wife found the containers and emptied the bastards, which caused my forced withdrawal (the bitch), nevermind the expense when I'm looking at bankruptcy anyway.

If you can keep it sensible, I think you can enjoy the G in its intended form for leisure use only, and if I've only a small amount, I won't be able to go nuts on it like before (maybe wishful thinking). I also found on a couple of occasions when I did use it half sensibly that mixed with vodka and mango juice in small proportions, that it made a good nitecap (well, until you wake up under 3 hrs later and need to do the same thing).

I'm intrigued by the medicinal use as Lyrica for sleep disorder, and would like to try that, instead of sleeping tabs.

Incidentally, I found when I was taking stilnocht tabs, that if I took multiples instead of one tab, that the effect was pretty good, and gave a decent high. At nine tabs though I was talking loudly to the dressing gown hanging from the bedroom door (on a visit to my parents) and my mother came into the room to see who I was talking to! (I'm 41 by the way)

As for using G longer term, I think a sensible (addicts don't do sensible things though) policy would be to ensure that you have enough baclofen or benzos or even alcohol as a last resort, to ensure that you can detox yourself over a week without having to leave the house, and ensure you tell someone what you are doing, so they aren't shocked when you start calling them about the Sasquatch in the bathroom, and the jihadis in the living room if you forget and go cold turkey for any reason.

Also, I think you need to think carefully what you will tell the ambulance crew or doctors should you find yourself yet again coming to in an unfamiliar hospital unable to speak. That was another point I forgot to mention - each time I was hospitalised, I couldnt speak for hours after admission - I could open mouth, but nothing would come out:!

It would of course be better to steer clear of it altogether, but again that would be the sensible thing to do. Anyway, I'm two weeks clear of the stuff, and can't get any more for at least 5 days as my other half took time off to supervise me at home, after the last intensive care trip. I really don't want to end up in the icu again, cos it frightens the life out of you when you find out how close to checking out permanently you came. Well, it scared hell out of me.

The last point of note for me was the speed with which you go from being half normal one minute, to totally gone in the blink of an eye without any warning at all8o then coming to with tubes down throat and choking on phlegm surrounded by docs/nurses. I tried to get out of hospital quickly after I came to, but was told they'd section me if I tried to leave8o

Just some musings I guess. But probably the most pertinent point about gbl for me is just how strong it is in relation to dose. As an alcoholic (albeit not drinking) I tend to view all liquids in relation to alcohol, so like an idiot, poured from the bottle of g (through a squirt hole I'd made in the top) into a glass of coke instead of measuring it like a chemical. I've never been knocked out as fast in my life (quicker than an anaesthetic) and I'm 6'4 and 18st. The stuff is nuclear strength in relation to the price of it, compared to anything else.

Just some ramblings.
 
Indeed. Forgot about that. Could see it being useful for alcohol detox. Better than bloody Librium anyway :D

Tell you somet, Librium is well under rated as a benzo, it's very nice... Dunno about for alcohol detox like.

***EDIT***

I had librium for my geeb detox and it worked great apart from the tremors which it did eff all for.
 
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