• MDMA &
    Empathogenic
    Drugs

    Welcome Guest!

The Big & Dandy 5-APB Thread

Just received 250mg of 5-APB HydroChloride salt. Supposedly, most of the 6-APB and 5-APB on the market is the succinate acid form, which (again, supposedly - can anyone confirm?) holds 40% more actual 5-APB molecules per mg. Been a long while since I've tried this one, so I'm quite looking forward to it. As far as I remember (from my early trials) it was more potent than 6-APB but not quite as enjoyable. Perhaps I'll change my mind, since the trials were based off an early synth.
 
ungelesene_bettlek said:
is there actually a rational explanation for the good synergy between 5-APB and 6-APB? both compounds act as serotonin receptor agonists and monoamine releasers, correct? but what are the differences? which one has stronger affinity to which serotonin receptors, and how are the ratios of serotonin/noradrenaline/dopamine release?
Click to expand...

Going by my own experiences and the release values for 5-APDB and 6-APDB the 5's are mostly serotonin releasers with a lot less dopamine release and don't have quite the stimulation or rush, while the 6's are more dopaminergic, rushy, and in general pleasurable - however 6-APB isn't quite as lovey as say MDMA imo and this is where adding in 5-APB works great as it adds in all the extra empathy and makes it a wonderful combination that feels significantly better than MDMA to me :)

I think the magic of the combination is that while adding a mostly dopaminergic stimulant like 4-FA, 2-FMA, Amphetamine etc to 5-APB would make something like a longer lasting trippier MDMA - this combination makes for both more stimulation than MDMA *and* a LOT more love, which is a wonderful thing to have :D

Also, I'm not sure why this happens but in my experience the length of the peak nearly doubles for me when I take this combination, from 4-5 hours to 8-9.
 
Mixing 5-APB with 2-FMA had less than expected results. It seemed to increase the stimulation but little increase in euphoria or other enjoyable effects. I wonder if this is because it is a 5HT2C agonist (limiting Dopamine and Norepinephrine).
 
Would like to try this but doubt any of the websites can be trusted!
 
^ curious myself as i had fun with 5/6 combo pellets...
can't help but wonder if the new '5apb hcl' is a way of shifting 5-it that nobody will buy

have read the thread but havent seen any posts describing duration.
is it another looooooong one like 6apb ?
does have the visual quality ?
 
HCl is 10% more potent per unit weight.

5-APB has a mass of 175 g/mol

Succinic acid (118 g/mol) is diprotic so one molecule neutralises two APB molecules to give a dicaionic salt. Mass (175*2+118)=468
468/2 to get the effective molar mass of 234.

HCl weighs 36.5 g/mol and neutralises one APB molecule, giving a mass of 211.

234/211 = 1.11 - which makes it 11% stronger weight for weight assuming no other factors come into play.
(211/243 = 0.90 is the factor if you want to convert your normal (succinate) dose to one for HCl.
 
Last edited:
Had a great time on 5-APB, though it was supposed to be MDMA. GS/MS test later revealed it to be be 5-APB. So when we dropped we assumed it was e. Anyway, I didn't get all that much lovey feeling as some describe, but overall felt quite happy and music especially sounded great. Had plenty of energy too. No trippiness for me, but my friend had some. Experience lasted awhile, but comedown was pretty easy physically and mentally, thought it was gradual and took some time.
 
Sepher said:
Yes, but in combo with 6-APB, dropping the 6 about an hour in, so first coupla hours was nearly all down to the 5 and insufflates easily, fast come up compared to 6-APB. It was good stuff. See my previous post on the 6-APB thread for comments on that combo.
Click to expand...

I read your post. So was it stronger than the succinate?
 
Can't compare, only had the HCl, vendors I use always out of stock of the succinate when I tried for it. General consensus from other users on another site I'm on is that yes, HCl seems to have more oomph than succinate as per Transform's post and hits faster / harder. Take that with the pinch of salt it deserves. It's definitely stronger weight for weight, or is more straightforwardly stimmy at least than 6-APB succinate I think, got more from combo of 5 & 6 @ 100mg each than I'd expect from 200mg ( or maybe even 250mg ) of 6 alone anyways, by a good bit I think. More testing needed.
 
Go together so well in combo, I'd rather have a 150mg mix of 5 & 6 than a gramme of md! All day long my friends :)
 
Transform said:
HCl is 10% more potent per unit weight.

5-APB has a mass of 175 g/mol

Succinic acid (118 g/mol) is diprotic so one molecule neutralises two APB molecules to give a dicaionic salt. Mass (175*2+118)=468
468/2 to get the effective molar mass of 234.

HCl weighs 36.5 g/mol and neutralises one APB molecule, giving a mass of 211.

234/211 = 1.11 - which makes it 11% stronger weight for weight assuming no other factors come into play.
(211/243 = 0.90 is the factor if you want to convert your normal (succinate) dose to one for HCl.
Click to expand...
according to some analysis, 5-APB succinate usually contains an excess of unreacted succinic acid. that's why the vendor's claim that 5-APB HCl is significantly more potent than the 5-APB succinate on the market is not that far-fetched. I would definitley recommend to start with a much lower dosage of 5-APB HCl when first trying this form of this compound. probably already 70-80 mg 5-APB HCl is equivalent to a standard dose of 100 mg of the usual 5-APB succinate.
 
I have tried 6-APB at ~120 mg and didnt like it that much, ok headspace and music sounded nice, but no euphoria and felt some nausea. Next time I will try a higher dose to see if that would give it the extra push i felt it needed.
Im going to a rave in about a month and im planning on trying out 5-APB there. Ive read a lot of positive comments about the 5/6-combo, but i want to try both compounds on their own first.
The only doubt i have about taking 5-APB on its own at a rave is that it is too mellow. What do you think? Is 5-APB too mellow for a rave, has anyone combined it with a small amount of amphetamine to give it some extra energy?
 
If you felt some nausea at that dose I'd assume it would get worse with a higher dose honestly. It's worth noting that going by the effects people experience - and going by the EC50 values for 5-APDB and 6-APDB - we can assume that 5-APB is mostly only serotonergic with very little dopaminergic action - even compared to MDMA which is vastly less dopaminergic than 6-APDB & 6-APB in itself.

Given that mostly/purely serotonergic compounds tend to be more anti-depressant than euphoric in action if you're looking for the 6-APB experience from 5-APB you'd have to push the dose up dramatically and at that point the excess in serotonin would likely produce nasty side effects.

Don't look for the 6-APB experience from this one, it's quite the different drug, despite sharing many similarities. Imo it's much more suitable for spending time with closed friends and loved ones as being more serotonergic at a similar dose results in more empathy and touch enhancement, but less of the mashed rushing and pushy euphoria of 6-APB.

For me personally though 5-APB's main purpose is to be used in combination with 6-APB. It's such a wonderful combination that far excels past either drug alone at any dose, the synergy is unreal. :)

I've heard good things about 5-APB and a low dose of amphetamine, saying it's much closer to 6-APB, so it might be worth a try - just don't push the doses too high as in my experience the APB's raise heart rate quite significantly when compared to other stimulants sometimes, and you don't want to put too much strain on your heart.
 
^

Thanks for the reply! Thats pretty much what i expected from what ive read about 5-APB. Im not looking for the same experience as 6-APB, what I would really want to do is just combine 5 and 6, but i feel like i have to try 5 on its own before combining it with 6. I try not to use strong serotonergic/dopaminergic drugs often, so i usually just use them at raves/parties. If i wait for a good moment to use 5-APB when just chilling with friends i will have to wait a long time and im too impatient for that :)

If i end up trying the 5-APB/amphetamine combo ill be sure to post here how it went! :)

A bit of-topic but the nausea i felt from 6 was during the come-up and peak, around the first 3 hours if i remember correctly, then it subsided. I think i will anyway try a higher dose(~150 mg) since that seems to be the sweet-spot for many and see if it gives me euphoria without much increase in side-effects. I was really quite suprised over the euphoria being almost nonexistent on 115 mg of 6-APB.
 
Seems I misread your post a little and read the 6-APB as 5-APB at the top. If you didn't find any euphoria at 120mg of 6-APB I'd question the quality, since I tend to need more than all my friends (they need 120-125mg, I prefer 150mg) but even I find 120mg a very euphoric experience, just not quite as intense as I personally prefer. I've previously had some lower quality off-white/VERY light tan 6-APB which gave me more side effects at a lower level and not as much of the euphoria, so that's a possibility. That said though, it's normal for a lot of people to get nausea on the come up, and the lack of positive effects at this level could be due to previous tolerance from MDMA and similar drugs.

If you want to get a good use out of 5-APB, I very much recommend either doing it at a quiet social event where you can spend more time sitting down and chatting with friends than dancing, or even just at home and spend lots of time rolling around under a blanket, playing some cool music, and in the shower - making the most of those epic tactile sensations! :D
 
You must log in or register to reply here.
Top