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Codeine & CWE Megathread: Version II - [insert witty title]

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So has a consensus been reached on timing of different drugs to best potentiate codeine? I seem to read an equal amount of posts where people say to take valium and promethazine before/after. And yeah ive done codeine in increasing doses like 10 times over about a year. I do feel the effects and enjoy it more than drinking alcohol, just alot less than my mate at a similar doses it seems which is why I wanna add in some valium. Seems to make sense to take valium before since its a potentiator, but again complete divide of exp codeine users saying to take it before/after.
 
gna grab sum pst <snip> style if i can tmoz, if not then il try grab a few boxes to do up at least 1200mg codeine batch, coz unless i got anythn else, im gna still need gfj with that and robo aswell. who knows why the fuk i have a codeine tolerance when ive only done it a few times now......
 
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indybreaker said:
gna grab sum pst hoyts style if i can tmoz, if not then il try grab a few boxes to do up at least 1200mg codeine batch, coz unless i got anythn else, im gna still need gfj with that and robo aswell. who knows why the fuk i have a codeine tolerance when ive only done it a few times now......
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Hey indybreaker,

Maybe you're expecting too much out of codeine? And even PST to an extent, though it can be quite strong. If you're used to more potent opiates like heroin, morphine, oxycodone, etc. then you'll likely find codeine rather disappointing. For a long time I didn't get any discernible effects from codeine phosphate at all. Only since kicking 32mg/daily Subutex cold turkey and reducing my heroin use to once or twice a fortnight did I start to feel it - and even then only really if I was hanging out. Opiates are cross tolerant as I'm sure you probably know, so if you have somewhat of a tolerance to any of the other opiates I mentioned before then that will translate to your codeine tolerance. Though, some people just have a natural tolerance to opiates. I have, and always have. Whatever the recommended dose is, I usually need to double it.

Ash. <3
 
cant work it out coz i got high as a motherfucker off pst the times ive made that, but have failed each time with codeine. scored some clonaz so wont be bothering with codeine for a while neway
 
Anti histamines ruin opiates for me, they help with the histamine reaction and nausea especially when you have little or no tolerance but if you don't need them I say avoid them an see how you go. Prometh, doxylamine and to a slightly lesser extent diphenhydramine seem to round off and blunt the euphoria, they sometimes even cause disphoria for me, especially doxylamine and it sucks having a relatively expensive high ruined by a shitty cheap pill. If I have a low tolerance I sometimes take as small amount of an antihistamine as I can (like 1/4 of a pill) about an hour or so before using, that way it doesn't suddenly step in and ruin a nice high you were enjoying, if youre still nauseous or itchy you can always take a bit more. Just my 2 cents.
 
For me to get a nod these days on just codiene I have to use an antihistamine.

I know what you mean about the euphoria being slightly deminished by them, exspecially in the first 2 hours. But after that rush if I haven't had an antihistamine then I won't nod off into the afternoon.
 
had a smoke which brought it on. nice n mild , irekon its moreso pst that im feelin rather then the codeine. either way, feelin good
 
indybreaker said:
cant work it out coz i got high as a motherfucker off pst the times ive made that, but have failed each time with codeine. scored some clonaz so wont be bothering with codeine for a while neway
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Most likely because codeine is a pro drug - it's mostly the metabolites that get you high, therefore if you're a poor metaboliser - ie. you have little of the enzyme CYP2D6 that converts codeine to morphine and it's other metabolites - you're not going to get as much from the drug as someone who converts it a lot more thoroughly.

On the other hand, pst contains all sorts of alkaloids, some of which, such as morphine, are active and don't need to be metabolised first - this is likely why you get effects from pst and not codeine, and in fact getting effects from pst and not codeine would be the typical reaction of someone who is deficient in CYP2D6.
 
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Standup said:
So has a consensus been reached on timing of different drugs to best potentiate codeine? I seem to read an equal amount of posts where people say to take valium and promethazine before/after. And yeah ive done codeine in increasing doses like 10 times over about a year. I do feel the effects and enjoy it more than drinking alcohol, just alot less than my mate at a similar doses it seems which is why I wanna add in some valium. Seems to make sense to take valium before since its a potentiator, but again complete divide of exp codeine users saying to take it before/after.
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IME it is best to take diazepam 20-40 minutes before dosing codeine. Promethazine beforehand definately lessens the high for me and I wouldn't take phenergan until atleast 45 minutes after dosing anymore, and I would wait closer to an hour unless the histamine reaction is getting unbearable. Diphenhydramine is the same, infact I would never take it again as I remember once it killed the high for me totally in its tracks.

I find Restavit/Doxylamine succinate is a good 1st gen antihistamine to take with codeine, because I can take it beforehand without diminishing the high of the codeine, I would usually take a Restavit or two half an hour before I drank my codeine. DXM I would usually dose 15-30 minutes before codeine, because I take it as Robitussin Dry Cough Forte (btw Re-distributed it has been rebranded this from Robitussin DX for literally years now, atleast where I live) I find it kicks in quicker than other potentiators I use which are generally tablets.

In regards to smoking weed, I find it is an excellent potentiator for codeine, that said, I am a daily smoker and I find I have to abstain from smoking weed that day until the codeine is kicking in for me if I want the best effects. Also, you can definately smoke too much and go past the sweet spot, I think a few cones is probably the sweet spot, maybe a handful if you smoke a lot but no more than that.

Totally off-topic in regards to CWE, but if anyone finds themselves in France you get this stuff called Paderyl (say pad-eh-reel) OTC that is pure codeine tablets, 19.5mg each. A pack of 20 of those is a fraction of what a box of codeine/para tablets cost in Australia. It's worth checking out if you are ever there and like your codeine. :)
 
drug_mentor said:
I find I have to abstain from smoking weed that day until the codeine is kicking in for me if I want the best effects.
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Yep, definetly do that every Sunday. Since I've dropped tobacco too I find that the green weed from my vape kicks the codeine in hugely.
Last week I had a drag on a ciggie after dosing and loved the rush I got, but found it ended my codiene high abruptly.

So that's it, no more ciggs full stop.
 
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^ Thats really weird, I find that tobaco/nicotine increases the effects of opiates for me for 2-5 minutes. I get the spins and it makes me feel a lot more noddy even though I am a regular (although not heavy) smoker. It definately increases the nausea for me quite a bit simultaneously but this doesn't really bother me as I just lie down and enjoy the increased effect until it passes.
 
so def wld come to being a poor metabolizer , coz i was high as a mofo from the pst, had to lie down for a while at one stage. codeine= shit (for me)
 
Google 'DNA Dose Genotyping' its a test you can get done that measures your metabolization (sp?)of certain cytochromes and enzimes for certain popular substances. I made a thread about it but it got closed as it was deemed as advertising
 
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