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Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

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It would be for pain and depression. I had a partial Tramadol script for my tailbone and when I took it, I noticed that it got rid of the depression that seems to come out worse on different days. I do have mild depression but some days it is moderate or severe.
I still have pain from a tailbone injury from a month or so ago. We will see how it goes.
 
My girlfriend is getting on Suboxone soon, she currently takes anywhere from 24-32mg of dilaudid a day and really wants to stop. She's not very strong willed as far as dealing with WD is concerned. I'm not sure how I can help her apart from being mentally supportive.

Everyone coming off ops, what do you wish you had in your life? I want be be as helpful as possible.
 
My girlfriend is getting on Suboxone soon, she currently takes anywhere from 24-32mg of dilaudid a day and really wants to stop. She's not very strong willed as far as dealing with WD is concerned. I'm not sure how I can help her apart from being mentally supportive.

Everyone coming off ops, what do you wish you had in your life? I want be be as helpful as possible.
Its really difficult to be in recovery AND be in a relationship. Do you do opiates? If you do, there is NO chance in HELL you're going to stay together if one of you is sober and one uses.
 
Its really difficult to be in recovery AND be in a relationship. Do you do opiates? If you do, there is NO chance in HELL you're going to stay together if one of you is sober and one uses.

^+1 sad but more often than not so true... I saw my sub doc today for the first time and when I told him about my once fiance his first reaction was (we were talking about the damage my addiction had done) say many couples break up when one is an opioid addict... He shut the fuck up when he learned the truth about why I never married tho. But that's another story...

Even though I'm glad I was not in a relationship when I decided to get clean, in certain ways having a supportive partner (albeit, not an addict) could make a world of difference for the better. But a using partner? I can't imagine that working out, even if they were also really trying to get clean. Just WAAAAY to much going on in either person's life to make being in a serious relationship even theoretically feasible. At the very least I would think some sort of "break," so as each could focus on their own self 100%, would be necessary, and we all know how well those generally work out :\
 
TDP! Right on the money! ;)

God damn, I don't know why I do this! I usually just dose my Suboxone every other day, 2MG. I try to always wait til I notice physical WD symptoms, amd THEN take it. I definitely can tell my receptors are bare :( oh, it hurts! I won't lie..I am SO looking forward to picking up my benzo script tomorrow..just because I have honestly not had ANY experience with benzos! I have only taken a TINY bit of a Xanax once, and that was only because I was dope sick :( I tried a bunch of other meds and herbal things but my sub doctor FINALLY said, "ok, let's try a benzo". I can't wait to get rid of this anxiety that always ruins my day.
 
Today I took LESS Suboxone than normal (I took 1 MG IVd), plus a new benzo my doctor is having me try (Lorazepam) and I nodded hard. I kept catching myself drifting in and out of nod land, waking up in a pool of drool. It was pretty unexpected, but nice :)
 
Yes, I've switched back to IV ROA, though I'm kind of pissed off because yesterday I miscalculated my water measurements and shot a whole milligram when I was thinking I was just doing .5.. Anyway, I'll keep each dose down to .3 max, then lower it from there.

Does anyone REALLY know for a fact that shooting buprenorphine does not speed up the elimination time? I ask because for one, I feel like each shot lasts a couple hours, withdrawals hit much faster, and I read that buprenex has a half life of 3 hours. Obviously that seems WAY too short, but I have a hard time believing that it doesn't leave the system much faster than sublingual. I've heard the argument that since IV bupe peaks within 10 minutes, you feel withdrawal sooner as the duration doesn't last as long due to the absence of a subtle onset. This kind of seems like bullshit to me though, because I feel like the duration of IV buprenorphine compared to an equivalent dosage of sublingual buprenorphine, lasts 1/2 as long.

Anyway, does anyone have any real evidence that can either validate or disprove this idea?
 
I've had to start shooting sub, I only was able to get 2mg, and split it up into 4 x .5mg, and I did the shots at +0 +5 +13 +19 hours.

Granted it was small, but I noticeably felt that there was a rise (obviously), and fall much quicker than Sublingual.
 
I've also noticed that I'm able to get 100% effects from 30mg of IV oxycodone if I've been shooting a total of .8 mg of bupe a day. I can use 5 hours after my last .2-3 shot, and feel great from the oxy. However, when I shoot 12 hours after taking .5mg sublingual, I get about 60% effects, and according to BA .5mg is equivalent to around .15mg IV (due to SL 30% BA)..
 
I have a question.. I know a lot of people say they are on 2mg of suboxone a day and that 2mg is good enough for them. What I am wondering is, Do you actually take 2mg of Suboxone/Subutex Film/Pill Sublingualy? The reason I ask is I have read many places that the Sublingual Bioavailability of Suboxone is around 33% So I am wondering if people on Small Doses of Suboxone (2mg or less) Take Say 4/5 mg a day to adjust to the bioavailibility or do you actually take only 2mg?

One of the reasons I ask is, I want to have some fun and get high for a while off my Suboxone. I take 4mg of Suboxone Film everyday. I have read from many people that if you take 2mg or less of Suboxone you will be able to get higher sooner than if you take a higher dose, so I am thinking of Switching down to only taking 2mg a day before I get high and I was just wondering if people actually take 2mg, or a little more to adjust for the bioavailability. I have waited less than 48 hours after taking Suboxone to use Dope and I have felt the full effects. I am kind of wondering to myself even though I am taking 4mg of Suboxone a day if really my body is only absorbing much less because of the bioavailability.

I am hoping to use on the 9th of April, would it be advisable to start cutting my dose everyday next week and than stop using suboxone on the 7th? Would that help get rid of some of the Build up in my body because I have been using Suboxone for a year or more?

Thanks for any and all answers. Also really sorry if I am repeating certain questions. I have read around this Opiate/Opioid Forum and a few others.. but I still had these specific questions.
 
Most people I know of who say they take 2mg of suboxone are not adjusting for BA. Then again, many of these folks shoot their suboxone, so in their case they are pretty much getting 2mg of actual bupe in their system as the BA for IV is pretty much 100%.

Even if you're only taking 2mg of suboxone sublingually, you're still not going to be able to get nearly as high as you would be without having any bupe in your system. Sure, it's way easier to get high on a full agonist when taking 2mg of suboxone as opposed to 8mg, but even with just taking 2mg you'll still have enough bupe in your system to require taking significantly more of your full agonist to get high than you would if you didn't have any bupe in your system at all.

So, yes, you'll be able to get high. And yes, it won't hurt to cut down to just 2mg sublingual for a while before you plan to take a break and use full agonists. However, you'll still have a little bupe in your system. Thus you will need to take more than you normally would of your full agonist you want to use to get high.

When I was on 2mg, and wanted to use oxycodone to get high, I'd have to take 60mg to get a nice high, as opposed to my normal (no bupe in my system, no or small tolerance to opioids) 30mg oxycodone.

Using potentiators like tagamet will help you get high when you wanna take that full agonist btw.
 
When on it at my highest, I could go 48 hours on 4mg sublingal (used listerine to increase BA), but 4mg IV lasted me maybe 30. I never really gave it much thought tho. I had such trouble not puking w/ 'em in my mouth, that I only IV'd them after starting.

Besides, once you get to <1mg doses, you need a decent scale to be accurate. For IV, just make the whole pill at once, put in a little IPA, and it' ready to go for the week.
 
Something just dawned on me and sorry if this has been asked before but wouldn't all the half-life & taper charts for bupe be incorrect since depending on how you administer the dose would affect bioavailability and since no route has 100% bioavailability then youd think your taking more than you actually are, thus fucking up how ud read the chart?
 
No, because you just got to basically divide the chart dosages by .3, and you'll get the actual BA(for sublingual). Also, IV has 100% BA (if your giving your solution a proper time to completely dissolve, and you're not missing your shots. For instance, the chart that says 16mg/day with chronic use leads to a build up of 40mg of buprenorphine at any given time, would actually equate to a total of 8.4mg(or something like that-clonazepam may be fucking with my mathematical skills currently, and I'm left brain anyway).

Also in response to toothpastedog, I had been taking 1mg sublingually up until the last week when I started to IV it again, as it actually is helping me a bit since I'm coming back from a slip and I feel a need to inject (I figure, it's better bupe than heroin or cocaine). But like I said in my previous post, I feel like IV administration of buprenorphine does somehow change how the drug is metabolized, as when I was on 1mg/day IV, I could shoot 30mg of oxy, or 2.5mg of oxymorphone and get a true high out of it, but when I take 1mg/day sublingual, I seem to feel only around 60% of the effects of a full agonist.

I've also switched between several routes of administration during my years on bupe, mainly SL, rectal, and IV, and I found that the way they translate is sort of strange. When I would inject 1mg a day(breaking my shots in to four .25mg doses), and switch to sniffing, I could sniff 1mg a day, and I felt fine, in fact even a bit more buzzed then IV, AND plus, one dose would last 24 hours, It seems like whatever the ammount you shoot in one dose, is pretty much the ammount (when translated into the other ROA BA) you need to take sublingually, maybey a little more.

This is what makes me feel like IV bupe actually does leave the system a whole lot faster than Sublingual bupe does (perhaps when you inject, that given dosage is what would be needed sublingually for the same effect, equating the BA of course). Another example is that I went through a period where I was shooting 6-8mg of buprenorphine a day for a couple of months (2mg shots=~6mg sublingual), and I decided to switch back to SL. I then took 4mg and felt a lot more euphoria and potency out of it then I had from 2mg IV, and this was without tapering. Sure, less is more, but you have to taper to experience this. So what I drew from these combined experiences is that either suboxone leaves your system exponentially faster when injected, OR, the naloxone does somehow tamper with the buprenorphine at the receptor site (though it does not block it)

I kind of believe that it just has to do with ROA, because I've shot subutex before, and noticed little difference, however the whole thing is confusing.

Anyway, I guess I have raised my tolerance now, as I'm IV'ing .8mg a day. I'm not too upset by it though, once I get some more money I'm going to try the whole loperamide thing to taper down, and try to kick the subs once and for all. I don't want to never take them again, but it would be great to not be Dependant, and be able to take them once every week or two for recreational purposes. (and to get a chance to see if I have that kind of will power)
 
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Help with copays

Just wanted to toss this out there, might help someone some.
My Dr gave me a card that take's care of my copay for suboxone. Covers up to $50 month and is good through 2012, Not sure if it is on the Suboxone website or not. For the people who go the Dr's for there Subs and have a copay on insurance for their scripts you might want to ask your Dr about it.
 
I think you hit the nail on the head ZNeg. I think maybe the tiny amount of naloxone plays a part in why the IV route doesn't last as long. I mean it doesn't make sense otherwise, usually the duration isn't affected based on which ROA you use.

I don't know, I'm not an IV user, nor a regular bupe user. But it makes sense the way you explained your theory.
 
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