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Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

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I have a vial of bacteriostatic water that I broke the seal off of months ago and it has been sitting on a warm, sunny windowsill since. Is it still ok to use since I haven't punctured it with a needle, or did breaking the seal and exposing it to heat spoil it?
 
I would be wary about using it since you have broken the seal, but since you haven't punctured it (thereby exposing to the elements?) it might be okay... big maybe as far as I know. It would really come down to the type of vial it was stored in. Some have seals that are just meant to ensure it's not been used, while I assume others might have a seal that actually are more about keeping it sterile.
 
More Bupe Questions... For the Obsessed Experts... I'm obsessed :o

Anyways if you follow my postings I was in the hellish underground of heroin addiction for about 4 years.

I learned from BL to do micron filtering and have been IVing the films and strips for some time now.

Thanks for responding to my swollen feet post two days ago guys and it must of been the falling asleep in the

chair that messed with the circulation. You were right though not bupe related. BL experts your medical knowledge is really impressive, how did you learn what you know?

My bupe conversion process is like this I follow the micron filtering protocol to a T and sometimes will filter through two micron filters. I have made concentrations of bupe ranging from 1mg/ML which is what I'm using now with the 2mg Tabs to 4mg/ml with the films.

My questions are if you can answer them are:
1. What is the highest bupe concentration you have made as in whats the highest mg/ML you have made and used successfully?

2 . What do you think is the highest concentration bupe will hold using tabs/films and micronfiltering as a means to create the solution?

3. What is actually better for IMing/Iving any preference... I have heard answers before for the films but were you BLers just referring to IM bupe or IV as well?

4. When you were tapering down how much discomfort were you in and how much dosage did you drop per day?

5. I want to get down and then off of this stuff myself. I have read the duration of IM injections are longer half lifes then the IV counterpart is this even possible?

6. Where did you IM as in where did you inject on your body and how did you set up this rotation? I have noticed I use the ventroglute with 2mg which would be 2ML right not and I am sore for about 4 hours but am okay after about noon.

7. Also do you think there is a time limit to where the bupe needs to sit to fully dissolve in the syringe before micron filtering or do you think as long as there is nothing floating around were good to go?

8. Additionally, even if it takes a bit of pressure to get that damn syringe to push the contents through the micron filter whats a way to know you have not broken the filter?.. as long as the stuff goes through can we assume the filter has done its job?

9. In the advanced drug discussion threads I asked about the microcellulose in films the answer sekio gave was that this is a plant based material that when IV'ed/ IMed will just break down into sugars and harmless stuff so its okay to be injecting. Anyways my friends thank you so much for reading this long ass post and if you can answer whatever you can once again I appreciate it.

10. This is for the be all end all of my bupe questions. You guy's are the shit. I have respect for all you guys and the time you put into educating yourselves on these subjects... I want to make a toast to the underground scholars of bluelight =D
 
1. What is the highest bupe concentration you have made as in whats the highest mg/ML you have made and used successfully?
*It's around 18mg/mL,

2 . What do you think is the highest concentration bupe will hold using tabs/films and micronfiltering as a means to create the solution?
*what is the exact question here, how long a solution is good for? Micron filter and use bacteriostatic water and you don't have to worry about bacteria.

3. What is actually better for IMing/Iving any preference... I have heard answers before for the films but were you BLers just referring to IM bupe or IV as well?
*The strips have way less active ingredients than the tablets, so the strips are safer.

-Inactive Ingredients in Suboxone Strips:
*Inactive Ingredients: polyethylene oxide, hydroxypropyl methylcellulose, maltitol, acesulfame potassium, lime flavor, citric acid, sodium citrate, FD&C yellow #6, and white ink.

-Inactive Ingredients in Suboxone tablets:
* lactose; mannitol; starch-maize; povidine; citric acid; sodium citrate, magnesium stearate, acesulfame potassium, and a lemon and lime flavour. ( oh yeah, and don't forget, naloxone is technically inactive ;) )


4. When you were tapering down how much discomfort were you in and how much dosage did you drop per day?
*When I tapered I would decrease my dosage by 50%. This was not uncomfortable until I got under 4mg, and then I began to experience W/D, though gabapentin helped me get through it, it usually took me about 5 days to completelu adjust to a new dose of suboxone when taken sublingually. When injecting, I adjust within a day or two. I suggest decreasing your dose by 10% every 4 days if you want to taper.

5. I want to get down and then off of this stuff myself. I have read the duration of IM injections are longer half lifes then the IV counterpart is this even possible?
*Yes, IV is perhaps the shortest lasting duration for all the ROA uses to take sublingual. Only IM with a micron filter. Alternatives could be rectal administration, which has a similar onset as IV, and a duration as long as insufflation.

6. Where did you IM as in where did you inject on your body and how did you set up this rotation? I have noticed I use the ventroglute with 2mg which would be 2ML right not and I am sore for about 4 hours but am okay after about noon.
*(can't help with this one, sorry!)

7. Also do you think there is a time limit to where the bupe needs to sit to fully dissolve in the syringe before micron filtering or do you think as long as there is nothing floating around were good to go?
*I notice a difference if I just throw a strip in a spoon and stir it around with my plunger for a minute and then draw it up, compared to when I let it sit for ten minutes. I say let it sit at least five minutes, then stir, then micron.


-these are all I can answer at this time hope it helps.
 
Most of this is covered real well by Zn3g, but I'd like to add to 4)

4. When you were tapering down how much discomfort were you in and how much dosage did you drop per day?

As Zn3g states, 50% is a good reduction to make when tapering.

I just have to warn you again, even if you're IMing or IVing your bupe you really cannot afford to taper in a week or three, especially if you've been using the bupe for a longer period of time. Essentially, I feel the ideal length of your bupe taper should be about 25% of the time you spend using bupe for maintenance or whatever. So if you've been using for a year, the entire length of a taper would be for three months. That's ideal ime/imo.

The minimum you must stay at each dose reduction to make the taper effective is 4-7days (four being kind of hit or miss).

And just to add, I have always found tapering down from whatever to 2mg to be easy as pie. Once I get to 2mg and have to go lower is when I start to feel (a little) shitty.
 
Excellent point TPD. When I got to 2mg (I found going under 4mg to be the part where it got hard), I let myself stabalize on that dose of for 14 days. It takes something like 12 days for the body to eliminate buprenorphine from the system, so I've always imagined that at these lower dosages, after about two weeks, yet he user should feel totally stable at the lower dose, as the previous half lifes have been shed.

That being said, with sublingual use, I found by day four my adjusted lower dose felt completely comfortable, even stronger than the previous ammount I had tapered down from. However, the only problems I faced we're that it seemed that the dose would wear off a bt quicker, and when it did, w/d symptoms would seem a bit more intense.
 
Started a Bup script today

So i started my buprenorphine script today. I was happy today as she gave me 4mg (2 2mg tabs) to be supervised with them in the chemist and 2 of the same ones to take away for later for some reason (which made me happy coz i could snort them),
for the rest of the week i am getting 2 x 8mg tabs to be superviced sublingual (16mg) in total.
Does anyone know the difference in bioavailasblility between sublingual and intranasal?
i dont know how hard they are going to watch me, i would imagine quite hard, i will go when its busy tho lol.
If the bio-avail aint that different then ill just go for sublingual.
i mean the 4mg sublingual and 4mg intranasal has held me today and i was pretty bad beforehand. (had been using about.7 a day for a long time)
anyway, hopefully it works for me
 
Why are you being supervised? Here in nyc my doc prescribes me 30 8mg a month for me to take home.

I've tried swallowing, disolving under tounge, snorting, and smoking bup/subs. Honestly, just let it disolve under your tounge. Snorting can make it "hit you faster" with a smaller ammount, but I would save that route for if you are very low on subs and need to get through multiple days.

Under the tounge is the best route for me. Maybe it will be different for you, but I've never felt any more "high" from a different ROA. Only way to feel the subs (recreationaly) for me is to mix it with benzos or tramadol.
 
Why are you taking buprenorphine? Are you taking it as part of treatment of an opiate dependency> Because it doesn't sound like it. It sounds like you want to use it in a way that is simply an extension of your addictive behaviour. Use it as directed. Otherwise, you won't stand a chance.
 
Whilst I have some understanding of what the above poster is trying to say, well done for getting on a program, all journeys start with one step just keep making those small steps and you will get there.

Best Wishes
 
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