• 💊 OTHER DRUGS 💊 Welcome Guest
    Posting Rules Bluelight Rules
    Notable Threads 1 Notable Threads 2
    Dangerous Combos Addiction Support
    Emergency Services Benzo Guide v.1
    Addiction Stories Scary Case Studies
    Biology, Pharmacology & Drugs 101
  • Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

Status
Not open for further replies.
Yeah, I also did some reading recently (half of which I did not get, I'm an artist, not a scientist haha) which talked about how when buprenorphine binds to receptors, it's actually repeatedly binding, seperating and then clinging back, over and over again, and perhaps during that incredibly small ammount of time that the bupe seperates, the naloxone sort of springs in for a second, and is nocked back off by the bupe. Maybey if this process is repeated, eventually the bupe sort of wears down, but the naloxone is so short acting that it doesn't take effect either.

I want to emphasize that I probably really over simplified that, and the latter half about the naloxone is my own theory.
 
My GF is the left brain, I'm the right.

Yeah I get it's a theory not a fact, but I agree with it, it makes sense that the naloxone would do SOMETHING when you IV it in tiny doses, it sure as hell works in larger doses when administered alone.
 
brokenpinky said:
Just wanted to toss this out there, might help someone some.
My Dr gave me a card that take's care of my copay for suboxone. Covers up to $50 month and is good through 2012, Not sure if it is on the Suboxone website or not. For the people who go the Dr's for there Subs and have a copay on insurance for their scripts you might want to ask your Dr about it.
Click to expand...

Totally - I just discovered this too. Even though I'll still be switching to generic subutex (or if generic suboxone is out when the time comes and is cheaper), shoot, I'll take free suboxone for the next couple months. Awesome.
 
toothpastedog said:
Totally - I just discovered this too. Even though I'll still be switching to generic subutex (or if generic suboxone is out when the time comes and is cheaper), shoot, I'll take free suboxone for the next couple months. Awesome.
Click to expand...
When My Dr gave me the card, I was thinking "cool" I have to pay through the nose for the Dr appointment, any little bit helps.
It still bugs the shit out of me that people seeking legit help for a real problem get treated like dirt and have to pay so much. I know people will say "you didn't have trouble finding the money for dope" you can pay for a visit.

That's just not the point. when people seek help most of the time they have nothing left and no where to turn. It should be easier and cheaper for someone to get back on track.
Well sorry for the soapbox ..
Peace. :)
 
Znegative said:
Yes, I've switched back to IV ROA, though I'm kind of pissed off because yesterday I miscalculated my water measurements and shot a whole milligram when I was thinking I was just doing .5.. Anyway, I'll keep each dose down to .3 max, then lower it from there.

Does anyone REALLY know for a fact that shooting buprenorphine does not speed up the elimination time? I ask because for one, I feel like each shot lasts a couple hours, withdrawals hit much faster, and I read that buprenex has a half life of 3 hours. Obviously that seems WAY too short, but I have a hard time believing that it doesn't leave the system much faster than sublingual. I've heard the argument that since IV bupe peaks within 10 minutes, you feel withdrawal sooner as the duration doesn't last as long due to the absence of a subtle onset. This kind of seems like bullshit to me though, because I feel like the duration of IV buprenorphine compared to an equivalent dosage of sublingual buprenorphine, lasts 1/2 as long.

Anyway, does anyone have any real evidence that can either validate or disprove this idea?
Click to expand...

Get micron filters. Switch to IM buprenorphine.

I only use 1 or 2 shots per day now.
 
Yeah, welcome back dude,
I'm just not that interested in IM buprenorphine. To be quite honest, I don't mind sublingual, Im just switching to IV for a while to calm my fetish (besides, I do get a slight rush). If I switch to another ROA (which I probably will pretty soon) it will be rectal.
 
Znegative said:
Yeah, welcome back dude,
I'm just not that interested in IM buprenorphine. To be quite honest, I don't mind sublingual, Im just switching to IV for a while to calm my fetish (besides, I do get a slight rush). If I switch to another ROA (which I probably will pretty soon) it will be rectal.
Click to expand...

Thats whats up!!
 
hello all u bluelighters! my names brian I'm new here, quick background about myself, I've been using opiates since i was 13(stole OCs from dads script) 4 years ago when i was 15 i broke my ankle boxing and swindled the Doc into giving me 15mg oxys and then 30s, seeing 12 doctors and w.e else an addict like myself does lol..im 19 now been on suboxone for a little over a year now and loveee the suboxone thread so i figured die join the community since Its helped me a great deal, i figure its time too give back! thank u and looking forward to meeting u guys, have a great day buepers!
 
brokenpinky said:
It still bugs the shit out of me that people seeking legit help for a real problem get treated like dirt and have to pay so much. I know people will say "you didn't have trouble finding the money for dope" you can pay for a visit.
Click to expand...

No, agreed. Plus my dope habits of the past always paled in comparison to how much this medical shit costs (hospital+doctor+med+more doctor...).
 
I wish I could get subutex but drs around here are crazy and won't prescribe it ... It's retarded but I'm seriously starting to think nalaxine causes unwanted side effects.

I even spit my salvia out after few minutes... Everytime I swallow it I fee like shir
 
cire113 said:
I wish I could get subutex but drs around here are crazy and won't prescribe it ... It's retarded but I'm seriously starting to think nalaxine causes unwanted side effects.

I even spit my salvia out after few minutes... Everytime I swallow it I fee like shir
Click to expand...

It's possible you're sensitive to it like me. They would not give subtex to me because I admitted to past IV use which is BS but what many dr's and clinics use as standard procedure in the US. There should be a test to determine if that's the case but there isn't. They have gone to great lengths to develop benzo tests which can ID what and/or how many different benzos you've used but nothing for naloxone sensitivity. The only thing that worked in my case is to taper down to 1 mg which is low enough to eliminate the sides....
 
Just wanted to bump this due to something I found on Friday.

As I have previously posted, I've switched to IV bupe (from 1mg SL/day, to around .8-9mg IV). Essentially I've raised my tolerance, as .9 mg IV is equivalent to about 3mg SL, though I really do not believe things are as simple as that.

As I said before, I have some skepticism regarding the elimination time of IV bupe being the same as sublingual administration. This Friday I used a full agonist about three hours after my last .25mg shot of bupe, and I got stupidly high. wayy more intoxicated than I had when I used heroin on top of my 1mg sublingual dosage.

What im starting to think is that perhaps buprenorphine still has the same elimination time from the system regardless of ROA, BUT, maybe IV injections of suboxone allow the bupe to disassociate a lot faster from the receptors.. Does anyone with any advanced knowledge in binding affinity etc have any thoughts, or have any other BL's recognized this as well?
 
Status
Not open for further replies.
Top