IMO the best drug for mediation is shrooms. I know its off topic a little bit but i have tried it on MDMA, LSD and a wide variety of substances. Nothing will ever be more spiritual than a mushroom trip. Nature bonds with me when im tripping on them. If u havnt tried it I recommend researching a bit about it

MDMA is prob the best substance for deep and meaningful conversations though, it truly makes you empathic towards everyone around you even strangers! Ive had the best convos ever on Molly. I just wish I could remember them, I actually forget what im saying half way through the sentence then ask my buddies what I was talking about they look at me eyes rolled and say hmm sorry man cant remember hahaa then we just hug each other. Its awesome!! Ahhh good memories.