Got a proper-sized batch of 1-propionyl-4-benzoylpiperazine, aka DM-235 to get done.
Got to prepare a wee little bit of the sunifiram the other day, got a beautiful-looking pure clear-white crystalline amide, and whilst it is without any recreational potential at least on its own, thats not what I'm looking for. But seriously, who'da thunk that OTC (used to be, pripsen powder is no longer available here, glad that several boxes of multiple 8g sachets of piperazine mono-hydrogenphosphate salt were kept back for a rainy day.
Tried a dose, and the results were impressive. Tested it from a baseline of such fatigue and shellshocked tired exhaustion owing to a full 4-5 day and night intensive work shift in the skunk-works without sleep, and it COMPLETELY cancelled out the effects of fatique, and even seemed to, surprisingly, ameliorate the WD from a few hundred mg of dipropionylmorphie and 120 of oxycodone (IV and rectally/nasally respectively) per day.
The fatique and performance impairment due to the fatigue just up and fucking vacated, quicker than tony bliar if the words 'The Hague' were mentioned in front of him. Of course this will not be something sustainable long term, but for occasional use, I LIKE this nootropic.
The finished diamide, starting from piperaziine looks gorgeous and clear-white crispy looking xtyls too...absolute stunner that turned out on the first time. Took a while to vap off residual benzoyl chloride, but once done, ended up with maybe 150-200mg of the finished DM-235 just for testing purposes. And it seems to have quite the antidepressant potential too.
Mode of action is potentiation of glutamatergic Ca++ ion flux at AMPA-type ionotropic glutamatergic receptors, where it is an allosteric positive modulator, or AMPAkine as these drugs are known. Potent in vivo too, 10-20mg and wow. Was planning to take some meth to keep up and active, since I had to, to be up early for a doc appt and to see limpet's social worker (who...shockingly...albeit an NT lady...fucking hell if he isn't godsdamned falling for her!) A real sweetie, and gorgeous too. Kinda bashfully shy in some respects, and omfg....its just...soooooooo cute
Haven't felt that way about anyone who wasn't either classically autie, Rett's or occasionally aspie in about 15-20 years! But this social worker gal....she just has this effect on him, has him actually looking forward to her appointments just to see her smile and the sound of her voice. Definitely got to get her something nice as a surprise for xmas. Not sure what yet. Thinking maybe a necklace chain in silver, and something to go n it that he'll forge from Ag himself, and electroplate in Pd. That or a bottle of champers. He doesn't drink the stuff himself, he can't do wines, he just...cannot bear the smell of them, or taste. But DEFINITELY got to find this great girl something to make her xmas. Perhaps even a sample of his best work, since she knows he's a chem guy and whilst that her finding out couldn't have been helped, she doesn't mind and won't drop him in it.
LC currently.....just awoke from an oxy, morphia and nitrazepam plus chlormethiazole (70-100mg or so nasally, 90-100mg IM, 10mg and about 0.6g orally respectively.)-induced restful sleep. The AMPAkine wasn't forceful, not 'in your face' but it was mightily effective, just felt like it was sitting there in the background, not like a typical stimulant at all in that there is no cardiovascular or adrenergic push. Just like...as if it was overclocking LC's wetware highly efficiently, and having him run at 150% without shoving it in his face. Could even SLEEP on withdrawal from the opioids seeing as the day the small sample was prepared, got a nap in after doing the work and rexy' first the intermediate monoamide, and then the finished 1,4-diamide, sunifiram/DM-235 itself.
Turned out to be, quite honestly, one of the loveliest looking successful projects, in the way those glassy-clear crunchy xtyls shimmered and glittered that LC has ever given birth unto
It was almost as if he could SEE the potential in those xtyls, glistening and shining away in their xtyl'n evapping dish after simple acetone rex' then water washing of the insoluble amide, then reforming it into lovely looking crystals again. With a lingering, although slight pleasant scent of benzoic acid at first. Smelled nice
Looked nicer. Worked nicer still. Methinks this is one LC is going to like, especially since his memory issues need fixing badly. He can remember his bank pin number now as actual numerical figures, although he had to rely on typing it out off paper many times at first until it encoded to muscle memory/kinaesthetic memory, and being nearly acalculic, although not quite, but very, very severely dyscalculic, on the DM-235 he actually managed to encode the information numerically. And the knowledge has remained. He doesn't have to type it by feel of position based on where cash-point buttons are positioned now.
Liking this
Its not at ALL pushy like an amphetamine or DARI, it just...its like having your natural equipment tuned to peak efficiency, and working with what you have, rather than a catecholamine release en-masse cracking the whip on one's CNS like a benign slave-driver. No appetite suppression either. In fact it's time to go grab that raspberry meringue roulade from the freezer, give it a dash of squirty spray cream from a can and munch down both those fuckers and a cottage pie. LC is hungry as, and that wouldn't be possible on uppers in the classic sense.
Would love to try pairing this with memantine.
And thinking of you, miss sadieface. Hope you and sham have a very good xmas
*hugs teh sadiemonster*
), but going with a carton of white grapefruit juice, some oxy and morphia, heminevrin cap (chlormethiazole) and a can of squirty spray cream. *LC playfully squirts a blob of canned extra-thick whipped cream on sadie's cute 'lil button schnozz, dips finger in it and licks it thoughtfully whilst batting eyelashes innocently*
